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Development And Assessment Of A Micro-Ct Based System For Quantifying Loaded Knee Joint Kinematics And Tissue Mechanics, Alexandra M. Blokker
Development And Assessment Of A Micro-Ct Based System For Quantifying Loaded Knee Joint Kinematics And Tissue Mechanics, Alexandra M. Blokker
Electronic Thesis and Dissertation Repository
Although anterior cruciate ligament (ACL) reconstruction is a highly developed surgical procedure, sub-optimal treatment outcomes persist. This can be partially attributed to an incomplete understanding of knee joint kinematics and regional tissue mechanic properties. A system for minimally-invasive investigation of knee joint kinematics and tissue mechanics under clinically relevant joint loads was developed to address this gap in understanding. A five degree-of-freedom knee joint motion simulator capable of dynamically loading intact human cadaveric knee joints to within 1% of user defined multi-axial target loads was developed. This simulator was uniquely designed to apply joint loads to a joint centered within …