Engineering Commons^™

Interrogating Autism From A Multidimensional Perspective: An Integrative Framework., Mohamed T. Ali

Electronic Theses and Dissertations

Autism Spectrum Disorder (ASD) is a condition characterized by social and behavioral impairments, affecting approximately 1 in every 44 children in the United States. Common symptoms include difficulties in communication, interpersonal interactions, and behavior. While symptoms can manifest as early as infancy, obtaining an accurate diagnosis may require multiple visits to a pediatric specialist due to the subjective nature of the assessment, which may yield varying scores from different specialists. Despite growing evidence of the role of differences in brain development and/or environmental and/or genetic factors in autism development, the exact pathology of this disorder has yet to be fully …

Motion And Emotion Estimation For Robotic Autism Intervention., Jacob M Berdichevsky

Electronic Theses and Dissertations

Robots have recently emerged as a novel approach to treating autism spectrum disorder (ASD). A robot can be programmed to interact with children with ASD in order to reinforce positive social skills in a non-threatening environment. In prior work, robots were employed in interaction sessions with ASD children, but their sensory and learning abilities were limited, while a human therapist was heavily involved in “puppeteering” the robot. The objective of this work is to create the next-generation autism robot that includes several new interactive and decision-making capabilities that are not found in prior technology. Two of the main features that …

Xylo-Bot: A Therapeutic Robot-Based Music Platform For Children With Autism, Huanghao Feng

Electronic Theses and Dissertations

Children with Autism Spectrum Disorder (ASD) experience deficits in verbal and nonverbal communication skills, including motor control, emotional facial expressions, and eye gaze / joint attention. This Ph.D. dissertation focuses on studying the feasibility and effectiveness of using a social robot, called NAO, and a toy music instrument, xylophone, at modeling and improving the social responses and behaviors of children with ASD. In our investigation, we designed an autonomous social interactive music teaching system to fulfill this mission.

A novel modular robot-music teaching system consisting of three modules is presented. Module 1 provides an autonomous self-awareness positioning system for the …

Clustering Heterogeneous Autism Spectrum Disorder Data., Mariem Boujelbene

Electronic Theses and Dissertations

Autism spectrum disorder (ASD) is a developmental disorder that affects communication and behavior. Several studies have been conducted in the past years to develop a better understanding of the disease and therefore a better diagnosis and a better treatment by analyzing diverse data sets consisting of behavioral surveys and tests, phenotype description, and brain imagery. However, data analysis is challenged by the diversity, complexity and heterogeneity of patient cases and by the need for integrating diverse data sets to reach a better understanding of ASD. The aim of our study is to mine homogeneous groups of patients from a heterogeneous …

A Cad System For Early Diagnosis Of Autism Using Different Imaging Modalities., Marwa Maher Tawfik Ismail

Electronic Theses and Dissertations

The term “autism spectrum disorder” (ASD) refers to a collection of neuro-developmental disorders that affect linguistic, behavioral, and social skills. Autism has many symptoms, most prominently, social impairment and repetitive behaviors. It is crucial to diagnose autism at an early stage for better assessment and investigation of this complex syndrome. There have been a lot of efforts to diagnose ASD using different techniques, such as imaging modalities, genetic techniques, and behavior reports. Imaging modalities have been extensively exploited for ASD diagnosis, and one of the most successful ones is Magnetic resonance imaging(MRI),where it has shown promise for the early diagnosis …

Studying Eye Gaze Of Children With Autism Spectrum Disorders In Interaction With A Social Robot, Huanghao Feng

Electronic Theses and Dissertations

Children with Autism Spectrum Disorders (ASDs) experience deficits in verbal and nonverbal communication skills including motor control, emotional facial expressions, and eye gaze attention. In this thesis, we focus on studying the feasibility and effectiveness of using a social robot, called NAO, at modeling and improving the social responses and behaviors of children with autism. In our investigation, we designed and developed two protocols to fulfill this mission. Since eye contact and gaze responses are important non-verbal cues in human's social communication and as the majority of individuals with ASD have difficulties regulating their gaze responses, in this thesis we …

Fast And Robust Hybrid Framework For Infant Brain Classification From Structural Mri : A Case Study For Early Diagnosis Of Autism., Amir Alansary

Electronic Theses and Dissertations

The ultimate goal of this work is to develop a computer-aided diagnosis (CAD) system for early autism diagnosis from infant structural magnetic resonance imaging (MRI). The vital step to achieve this goal is to get accurate segmentation of the different brain structures: whitematter, graymatter, and cerebrospinal fluid, which will be the main focus of this thesis. The proposed brain classification approach consists of two major steps. First, the brain is extracted based on the integration of a stochastic model that serves to learn the visual appearance of the brain texture, and a geometric model that preserves the brain geometry during …