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Fabrication Of Hybrid Optical Electrical Platforms For Potential Applications In Neuromodulation, Aneesha Kondapi Aug 2016

Fabrication Of Hybrid Optical Electrical Platforms For Potential Applications In Neuromodulation, Aneesha Kondapi

Electrical and Computer Engineering ETDs

State-of-the art neuromodulators are bulky, and they are mostly fabricated on rigid substrates. Furthermore, they are not provided with a feedback control loop re- sulting in undesired off-target effects. This thesis paves the way for fabrication of lightweight neural interfaces with the capability to implement closed-loop controlled neuromodulation down to a single-cell resolution. In this work, an approach based on hybrid optical-electrical devices to implement neuromodulation is presented. The rationale of this choice, design illustration, fabrication and characterization is discussed. In addition, a proof-of-concept neural interface is illustrated. Specif- ically, hybrid optical-electrical devices are developed based on inorganic thin films, …