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Full-Text Articles in Engineering
Silver Nanoparticles: The Immediate Benefits Of Low Bacterial Resistance And The Long-Term Risk Of Persistent Stress In Mammalian Cells, David Harold Ellis
Silver Nanoparticles: The Immediate Benefits Of Low Bacterial Resistance And The Long-Term Risk Of Persistent Stress In Mammalian Cells, David Harold Ellis
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Silver nanoparticles (AgNPs) are the fastest growing sector of nanotechnology, due mostly to their antibacterial properties. The antibacterial effectiveness of AgNPs is well known and derives from the shedding of silver ions which have multiple antibacterial targets in the bacterial cell. Due to their continuous release of ions and demonstrated antibacterial potency, some predict that AgNPs have a low potential for resistance development, which would make them a valuable asset in wound management. The ability for AgNPs to cause oxidative imbalance in mammalian cells is also well known, but the potential long-term impact of such a stress has not been …
Manipulation Of Gold Nanorod Physicochemical Properties To Enhance Biocompatibility, Uptake And Intracellular Preservation Of Optical Properties For Bio-Imaging And Plasmonic Photo-Therapeutic Applications, Anthony B. Polito
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Gold nanorods (GNRs) due to their tunable optical properties within the near infrared (NIR) region have been identified as strong candidates for new nano-based biomedical applications. Unfortunately, many have reported GNR cytotoxicity and it is still unclear how GNR aspect ratio (AR), surface charge and surface chemistry contribute to cellular association and cytotoxicity. GNR surface chemistry modifications have been reported to reduce cytotoxicity, however they can result in poor cellular uptake and loss of NIR optical properties preventing efficiency with bio-imaging and photo-thermal applications. The aim of this study was to determine if manipulation of GNR physicochemical properties could enhance …