Engineering Commons^™

Detecting Pathobiomes Using Machine Learning, Valerie Jackson, Valerie Jackson

Industrial Engineering Undergraduate Honors Theses

Machine learning is a field with high growth potential due to the overall continuous progressions, developments, advancements, and improvements caused by the way it is used to help interpret and use large amounts of data [1]. One type of data that can be collected and analyzed by these machine learning models is data that is associated with DNA and information that the DNA gives. The research will be focusing specifically on using machine learning technology to detect pathobiomes indicative of salmonella pork. The pathobiome associated with salmonella is very similar to others, and this causes a problem for classification/detection with …

Regression Analysis Of Pacing When Running A Marathon, Hawkin Starke

Industrial Engineering Undergraduate Honors Theses

Regression analysis can be an effective way of examining performance in the marathon event. By splitting up the race into segments or in runner terminology “splits” the significance of each segment as it relates to the total finish time can be explored. Because the idea of splits is already ingrained into the minds of runners, it makes intuitive sense to use these as the metrics to define a race. Additionally, marathons generally make participant age and gender date publicly available which can then be used to find trends within specific demographics. This tailors trends to smaller groups of people, making …

Characterizing Statin Use Among Prediabetic Patients With Predictive Analytics, Alexandra Gentile

Industrial Engineering Undergraduate Honors Theses

Diabetes is one of the leading causes of death in the United States and can cause severe impairments to those diagnosed. Prediabetes is a state when a patient has higher fasting plasma glucose levels than a non-diabetic person but is not quite high enough to be considered diabetes. Both diabetic and prediabetic patients are at higher risk for cardiovascular diseases (CVD), which is the leading cause of death in the United States. The primary form for prevention and treatment of CVD is through statin therapy. Statins are a class of medications used to treat and prevent CVD by limiting cholesterol …

Data Visualization Of Treatment Outcomes For Tuberculosis Patients, Joy Jenkins

Industrial Engineering Undergraduate Honors Theses

Tuberculosis is an infectious disease, and different treatments have been discovered over the years. However, patients may develop various drug resistance levels that affect the likelihood of becoming cured or dying. In this study, we sought to employ data visualization to explore the relationship between treatment trajectory, as indicated by smear and culture results in the follow-up tests and patient outcomes. A large sample of patients have been broken down by demographics including age, gender, and drug resistance status. Sankey diagrams were used to visualize the pathway progression of the patients over time split between two time periods- months 0-6 …

Simulating Alternative Tuberculosis Diagnosis Methods In Underdeveloped Countries, Luke Turner

Industrial Engineering Undergraduate Honors Theses

Tuberculosis is the deadliest infectious disease in the world; it is especially rampant in underdeveloped countries because they do not have the infrastructure, technology, or funding to properly combat the infection. However, the development of portable point-of-care diagnosis machines can reverse this epidemic as they far surpass conventional laboratory identification. The question now is where to place these machines, which is a difficult decision with a lack of data. Therefore, a flexible simulation model is created to test the implementation of these machines with different countries and configurations. The simulation tests the baseline model and three proposed implementations of the …

Transportation And Distribution Of Strategic National Stockpile Supplies In A Public Health Emergency, Olivia A. Goss

Industrial Engineering Undergraduate Honors Theses

In the event of a public health emergency in the United States, it is important that public

authorities are equipped to distribute medical supplies to every person in need as quickly as

possible. Federal guidelines state that all persons in an area affected by a public health

emergency should receive their medical countermeasures within 48 hours of the emergency’s

declaration. While the CDC has determined a general dispensing plan for each state and county

to follow, it is ultimately up to the state and county to formalize and implement detailed plans.

A body of academic literature focuses on optimizing the …

Dispensing Medical Countermeasures In Public Health Emergencies Via Home Health Agencies And Points Of Distribution, Anna Hudgeons

Industrial Engineering Undergraduate Honors Theses

A major concern regarding emergency preparedness on the state government level involves the handling and dispensing of the Strategic National Stockpile (SNS) of medicinal supplies. Each state is required to update and maintain a plan of action for dispensing SNS materials that would effectively provide care to the state’s population in times of distress. This research evaluates a state’s ability to dispense an adequate amount of medicine to her population in a timely manner, specifically after it has been received by the state government. Although simulation modeling has previously been utilized to replicate the dispensing process at pre-designated points of …

Exploring The Association Between Patient Waiting Time, No-Shows And Overbooking Strategy To Improve Efficiency In Health Care, Cam Tu M. Nguyen

Industrial Engineering Undergraduate Honors Theses

Many primary care clinics are using overbooking as a strategy to mitigate the negative impacts on operations and performance caused by patient nonattendance of appointments, also known as “no-shows”. However, overbooking tends to increase patient waiting time and worker overtime. It is also acknowledged that patient waiting time is associated with no-show behavior, yet there is a lack of observational study to quantify the relationship. The overall goal of this research is to explore the relationships between patient waiting time, no-show behavior and overbooking strategy in terms of clinic performance. Arena® simulation software is used to create a discrete-event simulation …

Improving Reliability Of Medical Device Tracking Using Unique Device Identification, John A. Bonfanti

Industrial Engineering Undergraduate Honors Theses

The term “disruptive innovation” has been the buzzword of industries looking to create technological advancements in their respective fields ever since the term was first coined in 1995. In order to invest in the future of the industry, companies are beginning to focus on new, innovative ideas that come into the market as a low-cost alternative to the sustaining innovations currently in place. Similar business-models can be seen in the healthcare industry, as physicians look to disruptive innovations to provide methods of diagnosis and treatment that are easier to perform and maintain. Companies, from medical device manufacturers to the hospitals …

Predicting Nonadherence Behavior Towards Mammography Screening Guidelines, Brian L. Trussell

Industrial Engineering Undergraduate Honors Theses

The goal of this research is to examine factors associated with nonadherence behavior toward mammography screening among U.S. women. The 2014 Behavioral Risk Factor Surveillance System (BRFSS) survey data was used for this study, allowing the model to represent a robust sample. A logistic regression model was developed to gain an understanding of influencing factors, including demographic, health-related and behavioral characteristics. Further analysis with logistic regression models stratified by age were conducted to control for the effect of age. The results show that demographic and health related information such as income, number of children, and BMI category can help intervention …