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Theses/Dissertations

Materials Science and Engineering

2011

Biomaterials

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Full-Text Articles in Engineering

Improved Manufacturing Methods Of Bovine Femur Samples For Ultrasonic Testing And Assessment Of Materials Through Contract Angle Measurement, Kevin Mathew Lopez Galang Sep 2011

Improved Manufacturing Methods Of Bovine Femur Samples For Ultrasonic Testing And Assessment Of Materials Through Contract Angle Measurement, Kevin Mathew Lopez Galang

Biomedical Engineering

At California Polytechnic State University of San Luis Obispo (Cal Poly), the Biomedical Engineering department (BMED) requires its students to take the course listed as “BMED 420: Principles of Biomaterial Designs.” BMED 420 has a required laboratory section every week throughout the duration of the course that is meant to be a supplemental tool for learning. During the lab sections, students perform experiments and exercises that are currently being implemented in the industry. Despite accuracy of the methods and experiments relative to their use in the industry, there is always room for improvement. The objective of this project will illustrate …


Roles Of Polymer Crosslinking Density And Crystallinity In Regulating Surface Characteristics And Pre-Osteoblastic Mc3t3 Cell Behavior, Kan Wang Aug 2011

Roles Of Polymer Crosslinking Density And Crystallinity In Regulating Surface Characteristics And Pre-Osteoblastic Mc3t3 Cell Behavior, Kan Wang

Doctoral Dissertations

This dissertation presents material design strategies to investigate cell-biomaterial interactions on specific biocompatible polymers and polymer blends by using mouse pre-osteoblastic MC3T3 cells aiming for potential applications in bone tissue engineering. Chapter 1 reviews some related background knowledge including polymeric biomaterials for tissue engineering, cell-biomaterial interaction, synthetic photo-crosslinkable and degradable polymers, and the effect of surface features on osteoblast cell responses. Chapter 2 presents photo-crosslinkable composites of poly(propylene fumarate) (PPF), an injectable and biodegradable polyester, and methacryl-polyhedral oligomeric silsesquioxane (mPOSS), which has eight methacryl groups tethered with a cage-like hybrid inorganic-organic nanostructure, for bone tissue engineering applications. Blending mPOSS with …