Engineering Commons^™

Machine-Learning-Powered Cyber-Physical Systems, Enrico Casella

Theses and Dissertations--Computer Science

In the last few years, we witnessed the revolution of the Internet of Things (IoT) paradigm and the consequent growth of Cyber-Physical Systems (CPSs). IoT devices, which include a plethora of smart interconnected sensors, actuators, and microcontrollers, have the ability to sense physical phenomena occurring in an environment and provide copious amounts of heterogeneous data about the functioning of a system. As a consequence, the large amounts of generated data represent an opportunity to adopt artificial intelligence and machine learning techniques that can be used to make informed decisions aimed at the optimization of such systems, thus enabling a variety …

Design, Development And Benchmarking Of Machine Learning Algorithms In Biomedical Applications, Qi Sun

Theses and Dissertations--Computer Science

Machine learning algorithms are becoming the most effective methods for knowledge discovery from high dimensional datasets. Machine learning seeks to construct predictive models through the analysis of large-scale heterogeneous data. While machine learning has been widely used in many domains including computer vision, natural language processing, product recommendation, its application in biomedical science for clinical diagnosis and treatment is only emerging. However, the wealthy amount of data in the biomedical domain offers not only challenges but also opportunities for machine learning. In this dissertation, we focus on three biomedical applications from vastly different domains to understand the opportunities and challenges …

Automated Testing And Bug Reproduction Of Android Apps, Yu Zhao

Theses and Dissertations--Computer Science

The large demand of mobile devices creates significant concerns about the quality of mobile applications (apps). The corresponding increase in app complexity has made app testing and maintenance activities more challenging. During app development phase, developers need to test the app in order to guarantee its quality before releasing it to the market. During the deployment phase, developers heavily rely on bug reports to reproduce failures reported by users. Because of the rapid releasing cycle of apps and limited human resources, it is difficult for developers to manually construct test cases for testing the apps or diagnose failures from a …

Novel Applications Of Machine Learning In Bioinformatics, Yi Zhang

Theses and Dissertations--Computer Science

Technological advances in next-generation sequencing and biomedical imaging have led to a rapid increase in biomedical data dimension and acquisition rate, which is challenging the conventional data analysis strategies. Modern machine learning techniques promise to leverage large data sets for finding hidden patterns within them, and for making accurate predictions. This dissertation aims to design novel machine learning-based models to transform biomedical big data into valuable biological insights. The research presented in this dissertation focuses on three bioinformatics domains: splice junction classification, gene regulatory network reconstruction, and lesion detection in mammograms.

A critical step in defining gene structures and mRNA …