Engineering Commons^™

Novel Applications Of Machine Learning In Bioinformatics, Yi Zhang

Theses and Dissertations--Computer Science

Technological advances in next-generation sequencing and biomedical imaging have led to a rapid increase in biomedical data dimension and acquisition rate, which is challenging the conventional data analysis strategies. Modern machine learning techniques promise to leverage large data sets for finding hidden patterns within them, and for making accurate predictions. This dissertation aims to design novel machine learning-based models to transform biomedical big data into valuable biological insights. The research presented in this dissertation focuses on three bioinformatics domains: splice junction classification, gene regulatory network reconstruction, and lesion detection in mammograms.

A critical step in defining gene structures and mRNA …

3d Body Tracking Using Deep Learning, Qingguo Xu

Theses and Dissertations--Computer Science

This thesis introduces a 3D body tracking system based on neutral networks and 3D geometry, which can robustly estimate body poses and accurate body joints. This system takes RGB-D data as input. Body poses and joints are firstly extracted from color image using deep learning approach. The estimated joints and skeletons are further translated to 3D space by using camera calibration information. This system is running at the rate of 3 4 frames per second. It can be used to any RGB-D sensors, such as Kinect, Intel RealSense [14] or any customized system with color depth calibrated. Comparing to the …