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Full-Text Articles in Engineering
Comparison Of Vibrational Spectroscopic Techniques For Quantification Of Water In Natural Deep Eutectic Solvents, Suha Elderderi, Pierre-Yves Sacré, Laura Wils, Igor Chourpa, Abdalla A. Elbashir, Philippe Hubert, Hugh Byrne, Leslie Boudesocque-Delaye, Eric Ziemons, Franck Bonnier Franck Bonnier
Comparison Of Vibrational Spectroscopic Techniques For Quantification Of Water In Natural Deep Eutectic Solvents, Suha Elderderi, Pierre-Yves Sacré, Laura Wils, Igor Chourpa, Abdalla A. Elbashir, Philippe Hubert, Hugh Byrne, Leslie Boudesocque-Delaye, Eric Ziemons, Franck Bonnier Franck Bonnier
Articles
Vibrational spectroscopic techniques, i.e., attenuated total reflectance infrared (ATRIR), near infrared spectroscopy (NIRS) and Raman spectroscopy (RS), coupled with Partial Least Squares Regression (PLSR), were evaluated as cost-effective label-free and reagent-free tools to monitor water content in Levulinic Acid/L-Proline (LALP) (2:1, mol/mol) Natural Deep Eutectic Solvent (NADES). ATR-IR delivered the best outcome of Root Mean Squared Error (RMSE) of Cross- Validation (CV) = 0.27% added water concentration, RMSE of Prediction (P) = 0.27% added water concentration and mean % relative error = 2.59%. Two NIRS instruments (benchtop and handheld) were also compared during the study, respectively yielding RMSECV = 0.35% …
Low-Cost Near Infrared Diffuse Optical Imaging System, Mohammed Z. Shakil, Chen Xu
Low-Cost Near Infrared Diffuse Optical Imaging System, Mohammed Z. Shakil, Chen Xu
Publications and Research
Diffuse Optical Tomography (DOT) and Optical Spectroscopy using near-infrared (NIR) diffused light has demonstrated great potential for the initial diagnosis of tumors and in the assessment of tumor vasculature response to neoadjuvant chemotherapy. The NIR technique utilizes intrinsic hemoglobin contrast, which is directly related to tumor angiogenesis development, a key process required for tumor growth and metastasis. The NIR diffuse tomography holds great promise in distinguishing early-stage invasive breast cancers from benign lesions. This technique also provides insight into tumor metabolism and tumor hypoxia, important indicators of tumor response to various forms of therapy. Currently, the high cost of the …
Noninvasive Optical Quantification Of Absolute Blood Flow, Blood Oxygenation, And Oxygen Consumption Rate In Exercising Skeletal Muscle, Katelyn Gurley, Yu Shang, Guoqiang Yu
Noninvasive Optical Quantification Of Absolute Blood Flow, Blood Oxygenation, And Oxygen Consumption Rate In Exercising Skeletal Muscle, Katelyn Gurley, Yu Shang, Guoqiang Yu
Biomedical Engineering Faculty Publications
This study investigates a method using novel hybrid diffuse optical spectroscopies [near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS)] to obtain continuous, noninvasive measurement of absolute blood flow (BF), blood oxygenation, and oxygen consumption rate (V̇O2) in exercising skeletal muscle. Healthy subjects (n=9) performed a handgrip exercise to increase BF and V̇O2 in forearm flexor muscles, while a hybrid optical probe on the skin surface directly monitored oxy-, deoxy-, and total hemoglobin concentrations ([HbO2], [Hb], and THC), tissue oxygen saturation (StO2), relative BF (rBF), and relative oxygen …