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Matrix Effect Study And Immunoassay Detection Using Electrolyte-Gated Graphene Biosensor, Jianbo Sun, Yuxin Liu
Matrix Effect Study And Immunoassay Detection Using Electrolyte-Gated Graphene Biosensor, Jianbo Sun, Yuxin Liu
Faculty & Staff Scholarship
Significant progress has been made on the development of electrolyte-gated graphene field effect transistor (EGGFET) biosensors over the last decade, yet they are still in the stage of proof-of-concept. In this work, we studied the electrolyte matrix effects, including its composition, pH and ionic strength, and demonstrate that variations in electrolyte matrices have a significant impact on the Fermi level of the graphene channel and the sensitivity of the EGGFET biosensors. This is attributed to the polarization-induced interaction between the electrolyte and the graphene at the interface which can lead to considerable modulation of the Fermi level of the graphene …
Matrix Effect Study And Immunoassay Detection Using Electrolyte-Gated Graphene Biosensor, Jianbo Sun, Yuxin Liu
Matrix Effect Study And Immunoassay Detection Using Electrolyte-Gated Graphene Biosensor, Jianbo Sun, Yuxin Liu
Faculty & Staff Scholarship
Significant progress has been made on the development of electrolyte-gated graphene field effect transistor (EGGFET) biosensors over the last decade, yet they are still in the stage of proof-of-concept. In this work, we studied the electrolyte matrix effects, including its composition, pH and ionic strength, and demonstrate that variations in electrolyte matrices have a significant impact on the Fermi level of the graphene channel and the sensitivity of the EGGFET biosensors. This is attributed to the polarization-induced interaction between the electrolyte and the graphene at the interface which can lead to considerable modulation of the Fermi level of the graphene …