Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- File Type
Articles 1 - 14 of 14
Full-Text Articles in Engineering
Polyethlyene Glycol Microgels To Deliver Bioactive Nerve Growth Factor, Jessica Stukel, Susan Thompson, Laurent Simon, Rebecca Willits
Polyethlyene Glycol Microgels To Deliver Bioactive Nerve Growth Factor, Jessica Stukel, Susan Thompson, Laurent Simon, Rebecca Willits
Rebecca K. Willits
Delivery of bioactive molecules is a critical step in fabricating materials for regenerative medicine, yet, this step is particularly challenging in hydrated scaffolds such as hydrogels. Although bulk photocrosslinked poly(ethylene glycol) (PEG) hydrogels have been used for a variety of tissue engineering applications, their capability as drug delivery scaffolds has been limited due to undesirable release profiles and reduction in bioactivity of molecules. To solve these problems, this article presents the fabrication of degradable PEG microgels, which are micron-sized spherical hydrogels, to deliver bioactive nerve growth factor (NGF). NGF release and activity was measured after encapsulation in microgels formed from …
Three-Dimensional Printing Fiber Reinforced Hydrogel Composites, Shannon Bakarich, Robert Gorkin Iii, Marc In Het Panhuis, Geoffrey Spinks
Three-Dimensional Printing Fiber Reinforced Hydrogel Composites, Shannon Bakarich, Robert Gorkin Iii, Marc In Het Panhuis, Geoffrey Spinks
Robert Gorkin III
An additive manufacturing process that combines digital modeling and 3D printing was used to prepare fiber reinforced hydrogels in a single-step process. The composite materials were fabricated by selectively pattering a combination of alginate/acrylamide gel precursor solution and an epoxy based UV-curable adhesive (Emax 904 Gel-SC) with an extrusion printer. UV irradiation was used to cure the two inks into a single composite material. Spatial control of fiber distribution within the digital models allowed for the fabrication of a series of materials with a spectrum of swelling behavior and mechanical properties with physical characteristics ranging from soft and wet to …
Phosphoric Acid-Imbibed Three-Dimensional Polyacrylamide/Poly(Vinyl Alcohol) Hyrdogel As A New Class Of High-Temperature Proton Exchange Membrane, Qunwei Tang, Kevin Huang, Guoging Qian, Brian Benicewicz
Phosphoric Acid-Imbibed Three-Dimensional Polyacrylamide/Poly(Vinyl Alcohol) Hyrdogel As A New Class Of High-Temperature Proton Exchange Membrane, Qunwei Tang, Kevin Huang, Guoging Qian, Brian Benicewicz
Kevin Huang
No abstract provided.
Synthesis Of Acrylic Acid Hydrogel By Y-Irradiation Cross-Linking Of Polyacrylic Acid In Aqueous Solution, Esmaiel Jabbari, Samyra Nozari
Synthesis Of Acrylic Acid Hydrogel By Y-Irradiation Cross-Linking Of Polyacrylic Acid In Aqueous Solution, Esmaiel Jabbari, Samyra Nozari
Esmaiel Jabbari
No abstract provided.
A Model For The Viscoelastic Behavior Of Nanofilled Hydrogel Composites Under Oscillatory Shear Loading, Alireza Sarvestani, Esmaiel Jabbari
A Model For The Viscoelastic Behavior Of Nanofilled Hydrogel Composites Under Oscillatory Shear Loading, Alireza Sarvestani, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
Release Characteristics Of A Model Plasmid Dna Encapsulated In Biodegradable Poly(Ethylene Glycol Fumarate)/Acrylamide Hydrogel Microspheres, Esmaiel Jabbari
Release Characteristics Of A Model Plasmid Dna Encapsulated In Biodegradable Poly(Ethylene Glycol Fumarate)/Acrylamide Hydrogel Microspheres, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
Gelation Characteristics And Osteogenic Differentiation Of Stromal Cells In Inert Hydrolytically Degradable Micellar Polyethylene Glycol Hydrogels, Seyedsina Moeinzadeh, Danial Barati, Xuezhong He, Esmaiel Jabbari
Gelation Characteristics And Osteogenic Differentiation Of Stromal Cells In Inert Hydrolytically Degradable Micellar Polyethylene Glycol Hydrogels, Seyedsina Moeinzadeh, Danial Barati, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
Effect Of Composition On Gelation Kinetics Of Unfilled And Nanoapatite-Filled Poly(Lactide-Ethylene Oxide-Fumarate) Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
Effect Of Composition On Gelation Kinetics Of Unfilled And Nanoapatite-Filled Poly(Lactide-Ethylene Oxide-Fumarate) Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
Combined Effect Of Osteopontin And Bmp-2 Derived Peptides Grafted To An Adhesive Hydrogel On Osteogenic And Vasculogenic Differentiation Of Marrow Stromal Cells, Xuezhong He, Xiaoming Yang, Esmaiel Jabbari
Combined Effect Of Osteopontin And Bmp-2 Derived Peptides Grafted To An Adhesive Hydrogel On Osteogenic And Vasculogenic Differentiation Of Marrow Stromal Cells, Xuezhong He, Xiaoming Yang, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
The Role Of Filler-Matrix Interaction On Viscoelastic Response Of Biomimetic Nanocomposite Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
The Role Of Filler-Matrix Interaction On Viscoelastic Response Of Biomimetic Nanocomposite Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
The effect of a glutamic acid (negatively charged) peptide (Glu6), which mimics the terminal region of the osteonectin glycoprotein of bone on the shear modulus of a synthetic hydorgel/apatite nanocomposite, was investigated. One end of the synthesized peptide was functionalized with an acrylate group (Ac-Glu6) to covalently attach the peptide to the hydrogel phase of the composite matrix. The addition of Ac-Glu6 to hydroxyapatite (HA) nanoparticles (50 nm in size) resulted in significant reinforcement of the shear modulus of the nanocomposite (~100% increase in elastic shear modulus). The reinforcement effect of the Glu6 peptide, a sequence in the terminal region …
Effect Of Surface Polarity On Wettability And Friction Coefficient Of Silicone Rubber/Poly(Acrylic Acid) Hydrogel Composite, Saeid Kheirandish, Esmaiel Jabbari
Effect Of Surface Polarity On Wettability And Friction Coefficient Of Silicone Rubber/Poly(Acrylic Acid) Hydrogel Composite, Saeid Kheirandish, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
In Vitro Osteogenic Differentiation Of Marrow Stromal Cells Encapsulated In Biodegradable Hydrogels, Johnna Temenoff, Hansoo Park, Esmaiel Jabbari, Tiffany Sheffield, Richard Lebaron, Catherine Ambrose, Antonios Mikos
In Vitro Osteogenic Differentiation Of Marrow Stromal Cells Encapsulated In Biodegradable Hydrogels, Johnna Temenoff, Hansoo Park, Esmaiel Jabbari, Tiffany Sheffield, Richard Lebaron, Catherine Ambrose, Antonios Mikos
Esmaiel Jabbari
No abstract provided.
Gelation And Degradation Characteristics Of In Situ Photo-Crosslinked Poly(L-Lactide-Co-Ethylene Oxide-Co-Fumarate) Hydrogels, Alireza Sarvestani, Weijie Xu, Xuezhong He, Esmaiel Jabbari
Gelation And Degradation Characteristics Of In Situ Photo-Crosslinked Poly(L-Lactide-Co-Ethylene Oxide-Co-Fumarate) Hydrogels, Alireza Sarvestani, Weijie Xu, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
Nanostructure Formation And Transition From Surface To Bulk Degradation In Polyethylene Glycol Gels Chain-Extended With Short Hydroxy Acid Segments, Seyedsina Moeinzadeh, Danial Barati, Samaneh Kamali Sarvestani, Ozan Karaman, Esmaiel Jabbari
Nanostructure Formation And Transition From Surface To Bulk Degradation In Polyethylene Glycol Gels Chain-Extended With Short Hydroxy Acid Segments, Seyedsina Moeinzadeh, Danial Barati, Samaneh Kamali Sarvestani, Ozan Karaman, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.