Engineering Commons^™

Recovery Of Carbon Dioxide From Flue Gases, Fahad Husain Al-Masabi

Theses

In this thesis, the modeling and simulation of the absorption of dilute CO₂ into falling film of aqueous solutions of a sterically hindered amine, 2-anino-2-methyl-1-propanol (AMP), was carried out using COMSOL Multiphysics Version 3.3. The operating cases were divided in two groups: (1) gas turbine operating cases (CO₂ 3 mol %) and (II) boiler operating cases (CO₂ 8.5 mol %). The key operating parameters for the studied cases are CO₂ partial pressure, operating temperature and amine concentration in the aqueous solution. The simulation focused on the following: (1) CO₂ Loading in aqueous AMP solution; (2) …

Design Of Drug Delivery Strategies Based On Well-Stirred Experiments, Kumud Kanneganti

Theses

Drugs are generally administered to the human body via injections (IV) or through other paths such as the buccal, nasal routes. The main consideration when designing a medication schedule is to maintain a therapeutic level of the drug in the body during the course of treatment. To achieve this goal, when IV drug therapy is selected, particular importance has to given to the dose to be injected and how to maintain the concentration of the pharmaceutical active ingredient (API) in the body between a Minimum Toxic Concentration (MTC) and a Minimum Effective Concentration (MEC). This therapeutic range varies with the …

Minimum Agitation Speed For Solid Suspension And Mixing Time In A Torispherical -Bottomed Pharmaceutical Stirred Tank Under Different Baffling Conditions, Dilanji Bhagya Wijayasekara

Theses

The minimum agitation speed, NS, required to just suspend solid particles dispersed in water was experimentally determined in this work for a glass-lined type of mixing tank provided with a torispherical bottom and agitated with a retreat-blade impeller under different baffling configurations. Ns for the same tank but equipped with a different agitation system, namely an axial impeller, was also experimentally determined for the purpose of comparing of performances of the two systems. The effect of impeller off- bottom clearance and the vessel's liquid level on the minimum agitation speed were also experimentally studied. Njs, was experimentally determined …

Enhanced Pervaporation Using A Novel Pump Configuration, Donough Patrick Shanahan

Theses

The pervaporation process is investigated in this work under the guises of process design improvements and process performance. Several avenues of research were investigated.

The main aim of the project was to investigate the use of liquid ring vacuum pumps for permeate recovery at laboratory and industrial scales. Due to technical and economical issues, these pumps were deemed unsuitable. This analysis then had to be extended further. Previous work investigated the use of dry vacuum pump systems on a lab scale and this work was extended to industrial scale simulations. Results from the lab scale process particularly those relating to …

Enhanced Vacuum Drying Through Improved Solvent Recovery, Reduced Process Cycle Times And Prediction Of Drying Duration, Diana Patricia Mesa Delgado

Theses

Drying of pharmaceuticals and fine chemicals is often accomplished under vacuum conditions to enhance energy efficiency and to avoid overheating of thermo sensitive materials. This project aims to study vacuum drying operations to obtain a better understanding of this process so as to optimize drying performance. This project obtained industrial data collected from a range companies in Ireland.

Pharmaceutical companies started assessing processes and making changes to drying processes from 2004 onwards; these initiatives are due to economic pressures, environmental issues and the Process Analytical Technology (PAT) initiative launched by the FDA in 2004.

Vacuum drying has been used in …