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Michael L.F. Lerch

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Full-Text Articles in Engineering

The Feasibility Study And Characterziation Of A Two-Dimensional Diode Array In “Magic Phantom” For High Dose Rate Brachytherapy Quality Assurance, A Espinoza, B Beeksma, M Petasecca, I Fuduli, C Porumb, D L. Cutajar, S Corde, M A. Jackson, M Lf Lerch, Anatoly B. Rosenfeld Nov 2013

The Feasibility Study And Characterziation Of A Two-Dimensional Diode Array In “Magic Phantom” For High Dose Rate Brachytherapy Quality Assurance, A Espinoza, B Beeksma, M Petasecca, I Fuduli, C Porumb, D L. Cutajar, S Corde, M A. Jackson, M Lf Lerch, Anatoly B. Rosenfeld

Michael L.F. Lerch

High dose rate (HDR) brachytherapy is a radiation treatment technique capable of delivering large dose rates to the tumor. Radiation is delivered using remote afterloaders to drive highly active sources (commonly 192Ir with an air KERMA strength range between 20 000 and 40 000 U, where 1 U = 1 uGy m2/h in air) through applicators directly into the patient's prescribed region of treatment. Due to the obvious ramifications of incorrect treatment while using such an active source, it is essential that there are methods for quality assurance (QA) that can directly and accurately verify the treatment plan and the …


Microbeam Radiation Therapy: A Monte Carlo Study Of The Influence Of The Source, Multislit Collimator, And Beam Divergence On Microbeams, Heidi Nettelbeck, George Takacs, Michael Lerch, Anatoly Rosenfeld Nov 2013

Microbeam Radiation Therapy: A Monte Carlo Study Of The Influence Of The Source, Multislit Collimator, And Beam Divergence On Microbeams, Heidi Nettelbeck, George Takacs, Michael Lerch, Anatoly Rosenfeld

Michael L.F. Lerch

Microbeam radiation therapy (MRT) is a new oncology method currently under development for the treatment of inoperable pediatric brain tumors. Monte Carlo simulation, or the computational study of radiation transport in matter, is often used in radiotherapy to theoretically estimate the dose required for treatment. However, its potential use in MRT dose planning systems is currently hindered by the significant discrepancies that have been observed between measured and theoretical dose and the PVDR (peak to valley dose ratio). The need to resolve these discrepancies is driven by the desirability of making MRT available to humans in the next few years. …


Large Area Silicon Microdosimeter For Dosimetry In High Let Space Radiation Fields: Charge Collection Study, Jayde Livingstone, Dale A. Prokopovich, Michael L. F Lerch, Marco Petasecca, Mark I. Reinhard, Hiroshi Yasuda, Marco Zaider, James F. Ziegler, Vincent L. Pisacane, John F. Dicello, Vladimir L. Perevertaylo, Anatoly B. Rosenfeld Nov 2013

Large Area Silicon Microdosimeter For Dosimetry In High Let Space Radiation Fields: Charge Collection Study, Jayde Livingstone, Dale A. Prokopovich, Michael L. F Lerch, Marco Petasecca, Mark I. Reinhard, Hiroshi Yasuda, Marco Zaider, James F. Ziegler, Vincent L. Pisacane, John F. Dicello, Vladimir L. Perevertaylo, Anatoly B. Rosenfeld

Michael L.F. Lerch

Silicon microdosimeters for the characterisation of mixed radiation fields relevant to the space radiation environment have been under continual development at the Centre for Medical Radiation Physics for over a decade. These devices are useful for the prediction of single event upsets in microelectronics and for radiation protection of spacecraft crew. The latest development in silicon microdosimetry is a family of large-area n-SOI microdosimeters for real-time dosimetry in space radiation environments. The response of n-SOI microdosimeters to 2 MeV H and 5.5 MeV He ions has been studied to investigate their charge collection characteristics. The studies have confirmed 100% yield …