Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Engineering
Micro-Patterned Surface Modification Of Poly(Dimethylsiloxane) (Pdms) Substrates For Tissue Engineering, Brad Winton, Mihail Ionescu, Chris Lukey, Mark Wilson, Ivan Nevirkovets, S. Dou
Micro-Patterned Surface Modification Of Poly(Dimethylsiloxane) (Pdms) Substrates For Tissue Engineering, Brad Winton, Mihail Ionescu, Chris Lukey, Mark Wilson, Ivan Nevirkovets, S. Dou
Mark R Wilson
Low energy metal ion implantation of poly(dimethylsiloxane) (PDMS) films simultaneously allows for the creation of complex and tuneable topographical features at the surface, while also enhancing the biocompatibility of the surface for biological applications. PDMS thick films were implanted with Mg, Ta, and Fe at constant dose. Cells cultured on all of the modified surfaces enjoyed an increase in viable cell count of over 440% when compared to the pristine surface, with the Fe implanted surface showing a 600% increase with a substantial increase in surface energy, which was reflected by the increased contact angle. This was achieved without any …