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Articles 1 - 13 of 13
Full-Text Articles in Engineering
Novel Methods For The Crystallization Of Thin Film Silicon, Shane Mcmahon
Novel Methods For The Crystallization Of Thin Film Silicon, Shane Mcmahon
Legacy Theses & Dissertations (2009 - 2024)
Underpinning much of the technological innovation over the past few decades in the fields of sensors, lighting, displays, and energy conversion has been thin-film electronics. While many of the surfaces in our environment have curvature, silicon wafers do not. Flexible electronics attempt to overcome this fundamental limitation in form factor. Flexible thin-film transistors (TFTs) can be fabricated over large areas to provide switching and driving elements for displays and other devices. While printable organic semiconductors have made significant advances over the past few years, they cannot match the performance capability, electrical quality, temperature compatibility, or stability of silicon. For this …
Photonic Grating Coupler Designs For Optical Benching, Eng Wen Ong
Photonic Grating Coupler Designs For Optical Benching, Eng Wen Ong
Legacy Theses & Dissertations (2009 - 2024)
Background: Silicon Photonics has been rapidly developing as a field. The primary reason for this is its lower operating costs and faster switching rates for use in big data centres. Instead of microns-wide copper lines to transmit signals, silicon photonic chips use waveguides, usually of silicon or silicon nitride. Photonic signals bypass the issues of resistive-capacitance lag (RC-lag) and resistive-heating encountered by copper lines. Additionally, a single waveguide may transmit multiple signals along different carrier wavelengths.
Investigation Of The Ms2 Bacteriophage Capsid As An Mri-Capable, Brain-Targeted Nanoparticle Platform, Stephanie M. Curley
Investigation Of The Ms2 Bacteriophage Capsid As An Mri-Capable, Brain-Targeted Nanoparticle Platform, Stephanie M. Curley
Legacy Theses & Dissertations (2009 - 2024)
Novel methods are needed to traverse the blood-brain barrier (BBB) and deliver drugs to specific targets in the brain. To this end, MS2 bacteriophage was explored as a multifunctional transport and targeting vector. The MS2 capsid exterior was modified with two different targeting moieties for delivery across the BBB and targeting specific regions of interest in the brain. Successful modification of MS2 capsids with a brain targeting peptide and NMDAR2D-targeting antibody was confirmed by immunoblotting and fluorescence detection. To measure transport efficiency of MS2 particles across an in vitro BBB model, a highly sensitive RT-qPCR protocol was developed and implemented. …
Impact Of Spiro Ammonium Electrolytes On Electric Double Layer Capacitors, Donald Derosa
Impact Of Spiro Ammonium Electrolytes On Electric Double Layer Capacitors, Donald Derosa
Legacy Theses & Dissertations (2009 - 2024)
Electric Double Layer Capacitors (EDLC) are high power (103 W kg-1), durable (>500,000 cycles) energy storage devices that are promising candidates for Hybrid Energy Storage Systems (HESS) , automotive and smart grid applications. EDLCs when coupled with lithium ion batteries in HESS configurations for hybrid vehicles have been shown to reduce capacity related degradation by a factor of 2 and impedance related degradation by 5.9. Despite these promising advantages, the adoption of EDLCs has been hampered due to concerns regarding the low volumetric and gravimetric energy density of these devices. Researchers have attempted to address these concerns through the …
Radiation Effects In Tantalum Oxide-Based Resistive Memory Devices, Joshua Stuart Holt
Radiation Effects In Tantalum Oxide-Based Resistive Memory Devices, Joshua Stuart Holt
Legacy Theses & Dissertations (2009 - 2024)
There is an increasing need for radiation-hardened electronics as space programs grow in number and scope. Scientific interest in long-term exploration, particularly in high-radiation environments such as Europa, as well as commercial interest in establishing permanent outposts, requires high tolerance of radiation effects. A flash memory device might survive for several years in low Earth orbit, but only a few days in orbit around Europa due to the extremely high levels of radiation encountered there. Meanwhile, commercial interests, including asteroid mining and building a base on the moon or Mars would require electronic systems that could survive for long periods …
Dna Functionalized Nanoparticles In Nanobiosensor And Sensor Array Development For Molecular Diagnostics And In Vitro Identification Of Biomolecules, Mustafa Salih Hizir
Dna Functionalized Nanoparticles In Nanobiosensor And Sensor Array Development For Molecular Diagnostics And In Vitro Identification Of Biomolecules, Mustafa Salih Hizir
Legacy Theses & Dissertations (2009 - 2024)
Nucleic acid technology along with vast variety of nanomaterials has demonstrated a great potential in many applications from biosensing studies to molecular diagnostics, from biomedical and bioanalytical research to environmental analysis. Especially short single stranded (ss) DNA molecules, called oligonucleotides, are extraordinary biopolymers featuring diverse functionality on the nanoparticles thanks to their high degree of programmability, target-specific binding or cleavage, molecular recognition ability, structure-switching capability, and unique interactions at the bio-nano interfaces. Among those, there have been many biosensing applications utilizing ss DNAs and numerous nanomaterials through various detection techniques such as fluorometric, colorimetric or electrochemical methods. Although many groundbreaking …
Economics Of R&D Specialization In The Semiconductor Industry, Kyun Kim
Economics Of R&D Specialization In The Semiconductor Industry, Kyun Kim
Legacy Theses & Dissertations (2009 - 2024)
Starting in the 1970s, specialized suppliers have entered the semiconductor industry to supply capital equipment, or tools, used in semiconductor manufacturing to downstream semiconductor companies. After the entry of these external suppliers, semiconductor chip producers began to rely in varying degrees on them for the R&D to improve the quality of capital equipment, while they themselves began to focus on design and production of chips. In my dissertation, I conduct an empirical and theoretical investigation to support my hypothesis that the difference in R&D incentives between the upstream suppliers and downstream chip manufacturers was the important reason for the emergence …
Growth Of Epitaxial Graphene On Single Crystal Copper Surfaces By Chemical Vapor Deposition, Tyler Rutley Mowll
Growth Of Epitaxial Graphene On Single Crystal Copper Surfaces By Chemical Vapor Deposition, Tyler Rutley Mowll
Legacy Theses & Dissertations (2009 - 2024)
Graphene is of significant interest due to its unique properties, such as high carrier mobility, mechanical strength, and thermal conductivity. Potential applications include next generation transistors, interconnects, biological and chemical sensing devices, and super capacitors. The research presented here addresses unresolved questions regarding the nucleation and growth of graphene by chemical vapor deposition (CVD) on the high index surfaces of copper single crystals. While much CVD graphene growth has been performed on copper foils, the polycrystalline nature of the foils renders large-scale single domain growth of graphene difficult. For this reason, many groups seek to reduce the nucleation rate of …
Development And Simulation Of Germanium P-I-N Infrared Detectors, Caitlin Rouse Philippi
Development And Simulation Of Germanium P-I-N Infrared Detectors, Caitlin Rouse Philippi
Legacy Theses & Dissertations (2009 - 2024)
Important factors for infrared photodetectors are that they are high-performing, low-cost devices. The performance can be characterized through the quantum efficiency, speed and device noise. Germanium (Ge) on silicon (Si) offers a comparable alternative to conventional groups III-V infrared detector materials such as InGaAs, InSb and HgCdTe in order to develop near-infrared (NIR) photodetector devices that operate with a high responsivity and a relatively low dark current without being cooled. As a Group IV material, Ge is compatible with Complementary Metal-Oxide-Semiconductor (CMOS) manufacturing which allows for a high-quality, high-throughput device for minimum cost. As a result of a thermally induced …
Zno Nanowires For Advanced X-Ray Source Applications, Vance Scott Robinson
Zno Nanowires For Advanced X-Ray Source Applications, Vance Scott Robinson
Legacy Theses & Dissertations (2009 - 2024)
X-ray system technology trends tend towards simpler, smaller and more efficient devices. A broad range of applications are driving contemporary efforts in X-ray source miniaturization: Portable and/or remote nondestructive evaluation; High throughput protein crystallography, invasive radiotherapy; monitoring fluid flow and particulate generation in situ; and portable radiography devices for battle-front or large scale disaster triage scenarios. Most of the x-ray sources for these applications follow a top-down approach focused on improving portability, and reducing mass and/or size.
Genetically Engineered Polypeptides As Biomimetic Light Harvesting Optical Antenna, Jason P. Seeley
Genetically Engineered Polypeptides As Biomimetic Light Harvesting Optical Antenna, Jason P. Seeley
Legacy Theses & Dissertations (2009 - 2024)
Natural resources useful for the generation of energy are limited. The development of efficient materials capable of utilizing the abundant free solar radiation is of considerable interest. Utilization of otherwise wasted energy sources, including solar radiation, is a progressive step in the quest for sustainable energy. Solar radiation incident upon the earth’s surface exceeds current energy requirements and motivates scientists to investigate and develop functional devices and nanomaterials including light harvesting complexes (LHC) capable of capturing solar radiation for energy conversion and storage.
Technology Development For Detection Of Circulating Disease Biomarkers From Liquid Biopsies Using Multifunctional Nanomaterials, Mustafa Balcioglu
Technology Development For Detection Of Circulating Disease Biomarkers From Liquid Biopsies Using Multifunctional Nanomaterials, Mustafa Balcioglu
Legacy Theses & Dissertations (2009 - 2024)
Despite the advance health care, devastating health conditions such as cancer and infectious diseases that affect populations worldwide are too often not diagnosed until morbid symptoms become apparent in the late phase. Obtaining an early and accurate diagnosis that reveal a hidden lethal threat before the disease becomes complicated may dramatically reduce the severity of its impact on the patient’s life and increase the probability of survival. For example, in the case of ovarian cancer, which is the fifth most common malignancy and the fifth leading cause of cancer mortality in women in the US, the 5-year relative survival is …
The Microfluidic Intravital Window : A Tool For Manipulation And Imaging Of The Tumor Microenvironment, Logan William Butt
The Microfluidic Intravital Window : A Tool For Manipulation And Imaging Of The Tumor Microenvironment, Logan William Butt
Legacy Theses & Dissertations (2009 - 2024)
The tumor microenvironment (TME) is a heterogeneous collection of both healthy and pathological cells, whose complex interactions hold the key for understanding and overcoming cancer. Metastasis leverages these complex interactions into a sophisticated process by which single cells from the tumor disseminate into the blood and form new colonies in other organ systems. Subsequent formation of tumors throughout the body, as a direct result of metastatic events, is responsible for most deaths related to cancer, making metastasis a necessary target for cancer therapy.