Engineering Commons^™

High-Throughput Assessment Of A Novel, Thiol-Acrylate Hydrogel For Tumor Spheroid Synthesis In A Microfluidic Device, Nathan Daniel Kersker

LSU Master's Theses

The extracellular environment plays an important role in regulating cell behavior. The mechanical, structural, and compositional properties of the extracellular matrix can determine the fate of the growing cells. Standard two-dimensional culturing in a flask fails to represent a native cellular environment. To create the native environment suitable for cells, hydrogels were previously studied. One of the most extensively studied synthetic hydrogels was a poly(ethylene glycol diacrylate) (PEGDA) hydrogel. However, the need for UV polymerization may introduce unwanted changes in cell morphology and viability. The hydrogel being proposed was a form of a thiol-acrylate hydrogel that can eliminate this problem …

A Systematic Investigation Of Condensation Heat Transfer Using Asymmetric Micro-Scale Surfaces, Emily Brown

LSU Master's Theses

Asymmetric surfaces been shown to inducing unidirectional motion in the Leidenfrost regime; however, very minimal research has been conducted to investigate whether these surface can enhance condensation through the same means. The investigation of heat transfer of ratchets in condensation is a relatively untapped area of study, specifically ratchets with superhydrophobic properties. Anticipated difficulty lies in creating surfaces features or coatings that retain the ratchets and can adequately sustain optimal wetting state of Cassie-Baxter required to improve heat transfer performance during condensation. This study serves to investigate whether ratchets are a feasible surface feature to enhance condensation heat transfer. First, …

Performance And Cost-Effectiveness Of Chip Seal And Microsurfacing In Flexible Pavements, Mohammad Zobair Ibne Bashar

LSU Master's Theses

Chip seal and microsurfacing are pavement maintenance activities typically used in relatively low traffic roads with the aim to reduce the rate of deterioration and to defer the need for costly rehabilitation activities. Chip seal is widely used in Louisiana, and Louisiana’s $6.3 million microsurfacing program is amongst the largest microsurfacing programs in the United States. As these surface treatments seal the road surface, the effectiveness of this treatment in such a setting has been a concern in recent years by linking it to moisture damage caused by the trapped moisture underneath the pavement. Furthermore, the cost-effectiveness and optimal timing …

Groundwater Modeling For Mississippi River Alluvial Aquifer Of Northeastern Louisiana, Ramazan Karakullukcu

LSU Master's Theses

The Mississippi River Alluvial Aquifer (MRAA) locates in northeastern Louisiana, extending from the north border of Louisiana and Arkansas to south central Louisiana and underlies the Mississippi River Valley. The MRAA is the second most used groundwater source with about 390 million gallons per day in 2010, which accounts for 25% of all groundwater withdrawals in Louisiana. The groundwater uses are mainly for irrigation, public supply and industries. The excessive groundwater pumping and the economic importance of the MRAA have drawn attention to build a groundwater model to study future water resources management and sustainability plans. The model is the …

Hyperspectral Imaging For Characterizing Single Plasmonic Nanostructure And Single-Cell Analysis, Nishir Sanatkumar Mehta

LSU Master's Theses

Orientation of plasmonic nanostructures is an important feature in many nanoscale applications such as photovoltaics, catalyst, biosensors DNA interactions, protein detections, hotspot of surface-enhanced Raman spectroscopy (SERS), and fluorescence resonant energy transfer (FRET) experiments. Silver nanocubes with significant spectral signatures between 400-700 nm are observed in this experimental research. Whereas study of single cells will enable the analysis of cell-to-cell variations within a heterogeneous population. These variations are important for further analysis and understanding of disease propagation, drug development, stem cell differentiation, embryos development, and how cells respond to each other and their environment. Adipose-derived mesenchymal stem cells possess the …

Study Of Rheology And Flow Behavior Of Magneto-Rheological Fluids Under The Influence Of A Magnetic Field And Its Potential Applications For Drilling And Completion Operations, John Edwin Estrada Giraldo

LSU Master's Theses

The use of magnetorheological fluids (MRF) is presented as an alternative to overcome some of the problems encountered in the drilling and completion of a well. The magnetorheological fluids can modify their rheological properties instantaneously under the influence of a magnetic field. In this thesis, MRF consist of a base fluid, magnetizable particles and a polymer that supports the particles. The magnetizable particles align in the direction of the magnetic field, thus modifying the rheology of the mixture. Because of this characteristic, the use of this fluid can have advantages in controlling fluid losses while drilling in narrow operating windows, …

Dispersing And Depositing Mose2 Onto Metal, Insulating, And Semiconducting Substrates Via Voltage-Controlled Deposition Technique, Kalyan Chakravarthy Byrisetty

LSU Master's Theses

In today’s world, consumer electronics are getting smaller than ever. These reductions in size are preceded by advancements in electronic materials engineering and related fields. The need for materials that have various properties and are suitable for applications also necessitated research on different materials. Growing research in the applications of graphene led the way to the discovery of materials that have similar properties to graphene. In this way, the transition metal di-chalcogenides (TMDCs) came into use for electrical engineering. Techniques are required to put TMDCs into application, however here we are going to explain the vital focus of our research …

Non-Parametric Classification Of Time Series Using Permutation Ordinal Statistics, Aldo Duarte Vera Tudela

LSU Master's Theses

The present thesis explores some approaches to classify time series without prior statistical information using the concept of permutation entropy. Motivated by the results from a previous published and relevant work that set similarity relationships between EEG time series, a reproduction of the proposed approach was performed giving negative results. The failure to reproduce those results led to the conclusion that the approach of building statistics from permutation patterns have to be complemented with another metric in order to be used for classification purposes. The concept of Total Variation Distance (TVD) was then used to develop three algorithms to classify …

Liquid Jet Penetration And Breakup In A Free Supersonic Gas Jet, Hansen Jones

LSU Master's Theses

In the testing of today’s rocket engines, both on large scale vertical test stands and smaller subscale horizontal component testing stands, it is extremely important to be able to accurately quantify and mitigate the thermal and acoustic loads the engines will generate on test stand infrastructure. Due to the large number of parameters that must be considered for many cases, development of a multi-phase computational code is under way to properly analyze and design water spray cooling systems used at NASA’s Stennis Space Center (SSC) and across other NASA centers. As such, a small-scale experiment has been conducted at Louisiana …

Computational Aerodynamics And Anatomical Characterization Of Laryngotracheal Stenosis In Children, William Poynot

LSU Master's Theses

Laryngotracheal stenosis (LTS) is a health condition in which an obstruction in the upper trachea can cause breathing difficulties and increased incidence of infection, among other symptoms. Occurring most commonly due to intubation in infants, LTS often requires corrective surgery. Currently, clinical methods of assessing the blockage region are simplistic and subjective, and it is challenging to determine the most effective surgical strategy for any given patient. In the present work, a comprehensive methodology is proposed for characterizing the stenosis region both in terms of its anatomical parameters and its corresponding aerodynamic properties. The combination of computational fluid dynamics (CFD) …

Coupled Chemical Pre-Oxidation And Aerobic Bioremediation Of Buried Mc252 Oil Across A Headlands Beach Profile, Olivia Bramlet

LSU Master's Theses

The release of MC252 crude oil following the Deepwater Horizon event has emphasized the need to investigate factors controlling the extent of contamination degradation in coastal environments. Dam structures created on Fourchon Beach, LA established conditions for PAH and n-alkane accumulation and burial along a vertical profile that persists today due to the anaerobic, often anoxic, and hypersaline conditions of the groundwater. The ability to remove the oxygen limitation present on in situ aerobic biodegradation of buried petroleum-based hydrocarbons in this environment was investigated through the coupled process of chemical oxidation and enhanced bioremediation using a proprietary formulation of activated …

Numerical Study Of Liquid Atomization And Breakup Using The Volume Of Fluid Method In Ansys Fluent, Sai Saran Kandati

LSU Master's Theses

The spherical metal particles produced from the centrifugal atomization process have been the topic of numerous theoretical, experimental and numerical studies from the past few years. This atomization process uses centrifugal force to break-up molten material into spherical droplets, which are quenched into solidified granules by the flow of cold air on the spherical droplets. In the present work, a transient three-dimensional multiphase CFD model is applied to three different materials: Molten slag, aqueous glycerol solution, and molten Ni-Nb to study the influence of the dimensionless parameters on the centrifugal atomization outcome.

Results from numerical experiments indicated that the droplet …

Evaluation Of Synthetic Cpt And Soil Boring Data By Various Spatial Interpolation Techniques, Md Habibur Rahman

LSU Master's Theses

In order to incorporate the influence of collected in-situ data, the spatial correlation between the data and the foundation needs to be explored. However, risk and uncertainty are the characteristics of the soil that cannot be eliminated. Statistical information of the soil property can be estimated from available field data obtained from testing at discrete locations across the site. In this research, several well-established spatial interpolation methods like ordinary kriging (OK), simple kriging (SK), inverse distance weight (IDW), spline, natural neighbor (NaN) and universal kriging (UK) were incorporated to evaluate the best method. Six CPT (Cone penetration test) (Tip Resistance …

Thin-Film Block Copolymers (Bcps) Self-Assembly As Versatile Patterning Scheme For Functional Nanomaterials, Le Zhang

LSU Master's Theses

Nanopattern generation is required for building various structural entities in every production process that involves nanostructures. Advancing nanopatterning technologies play an important role in developing and broadening the current nanopatterning technologies to meet up with the ever-demanding requirements in the realm of smaller feature sizes, smoother line-edge roughness (LER) and facile pattern transfer in pursuit of faster computer processors, better electrocatalysts and more compact and intelligent sensors, etc. Conventionally, patterning needs are heavily relied on photolithography, a technique that dominate chip-making industry for more than 50 years. However conventional photolithography is bounded by inherent resolution limits and difficult to be …

Identifying Key Factors Associated With High Risk Asthma Patients To Reduce The Cost Of Health Resources Utilization, Amani Ahmad

LSU Master's Theses

Asthma is associated with frequent use of primary health services and places a burden on the United States economy. Identifying key factors associated with increased cost of asthma is an essential step to improve practices of asthma management.

The aim of this study was to identify factors associated with over utilization of primary health services and increased cost via claims data and to explore the effectiveness of case management program in reducing overall asthma related cost.

Claims data analysis for Medicaid insured asthma patients in Louisiana was conducted. Asthma patients were identified using their ICD-9 and ICD-10 codes, forward variable …

Design, Simulation, And Construction Of An Ieee 14-Bus Power System, John Albert Boudreaux

LSU Master's Theses

Today’s bulk power system is massive, complex, and very dynamic. The U.S. power grid spans from coast to coast and even as far reaching as Canada. With the addition of new technologies such as renewable energies and power electronics to aid in power conversion and control, the power system grows more complex by the day. The most common approach of analyzing power system stability is through computer modeling and simulation. Due to the vast size and inaccessibility of transmission systems, real time testing can prove difficult. The motivation of this project was to design, simulate, and construct an IEEE 14 …

Evaluation Of Undrained Shear Strength And Soil Classification From Cone Penetration Test, Md Imran Hossain

LSU Master's Theses

The in-situ cone and piezocone penetration tests (CPT, PCPT) has been widely used by the geotechnical engineering community for subsurface soil characterization and classification, and for the evaluation of many engineering soil properties, such as undrained shear strength (s_u), unit weight (γ), constrained modulus (M), coefficient of consolidation (c_v), and stress history (OCR). The objective of this research study was to estimate the undrained shear strength of clayey soil using CPT/PCPT data in addition to some soil boring log data. At the same time, soil classification charts/methods based …

Development Of Long-Term Aging Factor For Asphalt Mixtures’ Cracking Resistance, Yucheng Shi

LSU Master's Theses

To characterize the cracking resistance of asphalt mixtures, semi-circular bend (SCB) test has been developed and subsequently accepted as a routine test in mixture design in Louisiana. However, SCB test requires specimens to be aged for five days in laboratory, which makes it not implementable in quality control (QC)/quality assurance (QA).

The primary project objective was to develop an aging factor to transfer the unaged SCB Jc to the aged SCB Jc. Specific objectives were to: (1) investigate the effect of laboratory aging on asphalt mixtures’ cracking resistance and asphalt binders’ rheological and chemical properties, (2) develop an aging …

A Study On Reduction Of Harmonic Distortion Caused By Ac Arc Furnaces, Venkata Mani Gadiraju

LSU Master's Theses

In AC arc furnaces, arc ignition is stabilized by inductors which are connected across its supply lines. They cause power factor degradation in the system. When furnaces are modelled as linear RL load, the arc nonlinearity reduces the impact of this degradation to a significant extent. Furnace Power factor is improved by the DC voltage on the arc. In this research study, power factor of AC furnaces is estimated on the assumption that DC voltage on the arc is constant and furnace operates in steady state. Primary objective of this research was to determine the power factor of the furnace …

Development Strategies For A Fractured, Heavy Oil Reservoir - Results From Numerical Simulations, German Albertovich Abzaletdinov

LSU Master's Theses

This research is focused on studying reservoir “N” in the Yarega heavy oilfield (YHOF) for development strategies and production optimization. YHOF is a naturally fractured heavy oil field where only very recently SAGD technology has been introduced. The motivation for this research is derived from the fact that SAGD employed in this field has so far resulted in early steam breakthrough leading to producer abandonment and new drilling, thus increasing costs. This study explores numerically different static and dynamic reservoir characterization models (single porosity versus dual porosity systems), and subsequent pressure-production history matched reservoir simulation for understanding heat and mass …

Evaluation Of Site Variability And Its Application In Design, Abu Hakim Muhammad Hasan Faisal

LSU Master's Theses

Geotechnical characterization has an important role in engineering geology as well as in implementation of any project. There are several variables and uncertainties involved in characterizing a project site. Four different sources of uncertainties represent the characterization of geotechnical variability, which include spatial variability, measurement error, statistical error and model bias. Spatial variability is expressed in terms of the mean, variance, and scale of fluctuation. Several statistical techniques such as the Gauge R & R, which includes X-Bar/R and ANOVA, and the Second Moment can be applied to compute site variability in terms of the coefficient of variations. Measurement error …

The Effect Of Rest Period On Fatigue Using Electromyography During Manual Lifting, Nandakumar Prabhakar

LSU Master's Theses

Manual materials handing (MMH) is the main cause and concern for injuries in the working population which lead to musculoskeletal disorders (MSDs). MSDs significantly contribute to the cost of workers’ compensation and loss of productivity, thus impacting economy of the United States. MSDs are mainly caused due to over exertion and fatigue experienced by workers involved in manual materials handling. In addition to over-exertion and fatigue, lack of short and frequent rest intervals between tasks contributes to the risk of MSDs. The objective of this research was to study the effect of rest period on muscle fatigue using electromyography (EMG) …

Micro Combustion Of Primary Reference Fuels In Narrow Heated Channels, Veerendra Naralasetti

LSU Master's Theses

Conventional fuel testing machines like CFR engines require large quantities of fuel. The current study seeks to overcome this limitation by introducing an alternative method using a microscale combustion reactor which consumes relatively small amounts of fuel (100-250 ml). For this reason, Primary Reference Fuels (PRF’s: volumetric mixtures of n-heptane and iso-octane) which are simple surrogates of gasoline are selected to test using micro reactor. The primary goal is to determine the effectiveness of using the micro reactor setup to differentiate fuels of different octane number. Experiments with stoichiometric PRF/air mixtures are performed inside a cylindrical quartz tube of 1mm …

Modeling Of The Veterinary Anesthetic Circuit, Corinne Viloria Duplantis

LSU Master's Theses

Anesthesia is used to sedate both humans and animals for surgery. In veterinary practice, breathing systems are often used to supply anesthetic gas to the patient. Occasionally, a large amount of pressure can build up in the breathing circuit. This high pressure, if unnoticed, can lead to fatal injury to the lungs of the veterinary patient. The maximum allowable pressure in the anesthetic circuit for small animals is 25 cmH₂O or 2450 Pa. As such, it is necessary to monitor oxygen flow rate (ranging from 0.1-4 LPM), pressure, oxygen rate, anesthetic composition, among other variables during an operation. …

Design And Performance Estimation Of A Low-Reynolds Number Unmanned Aircraft System, Sean Lauderdale King

LSU Master's Theses

The purpose of this thesis is to conceptually design a fixed-wing unmanned aircraft systems (UAS) with a higher flight-time and top stable speed than comparable systems. The vehicle adheres to specifications derived from the client, the market, and the Federal Aviation Administration (FAA). To broadly meet these requirements, the vehicle must fly for a minimum of three hours, return to the original flight path quickly if perturbed, and must be hand-launched. The vehicle designed must also have a large potential center of gravity movement to allow for customization of the planform and client customization.

An iterative design process was used …

Modeling And Analysis Of Thermal Effects On A Fractured Wellbore During Lost Circulation And Wellbore Strengthening Processes, Ze Wang

LSU Master's Theses

To successfully prevent fracture propagation and combat lost circulation, a thorough understanding of the stress state in the near-wellbore region with fractures is imperative. One important factor that is not yet fully understood is how temperature variation during lost circulation affects pre-existing or newly initiated fractures. To address this problem, a 3D finite element analysis was conducted in this study to simulate the transport processes and state of stresses in the near-wellbore region during mud invasion into fractures. To take the thermal effects into account, a thermo-poro-elasticity model was coupled with flow and heat transfer processes. This study included a …

Integrated Reservoir-Wellbore Nodal Analysis Workflow For Worst-Case Discharge Modeling, Florencia Anahi Vasquez Cordoba

LSU Master's Theses

According to the Bureau of Ocean Energy Management (BOEM), worst-case discharge (WCD) is the single highest possible daily flow rate of liquid hydrocarbon during an uncontrolled wellbore flow event [49]. The main objective of this research is to develop a workflow to calculate worst case discharge (WCD) volumes for a drilling scenario using an integrated reservoir-nodal analyses approach. Using robust integrated production modeling (IPM) tools, a nodal analysis workflow is developed to compute WCD volumes and rates that operators can use easily if they have IPM, or adapt to using a different software (including excel) in absence of IPM. A …

Predicting River Stage Using Recurrent Neural Networks, Eric Rohli

LSU Master's Theses

River stage prediction is an important problem in the water transportation industry. Accurate river stage predictions provide crucial information to barge and tow boat operators, port terminal captains, and lock management officials. Shallow river levels caused by prolonged drought impact the loading capacity of barges and tow boats. High river levels caused by excessive rainfall or snowmelt allow for greater tow capacities but make downstream transportation and lock management risky. Current academic river height prediction systems utilize either time series statistical analysis or machine learning algorithms to forecast future river heights, but systems that combine these two areas often limit …

Demonstration Of The Gas Assisted Gravity Drainage (Gagd) Process In Carbonate Rocks., Alok Jiteshkumar Shah

LSU Master's Theses

The Gas Assisted Gravity Drainage (GAGD) process was developed and patented by Dr. Rao at LSU in the early 2000s. The process involves the use of several existing or new vertical injection wells to inject gas and use the natural segregation of reservoir fluids from the density difference and the gravitational forces to displace the trapped oil and mobilize the oil downwards to be produced by a horizontal producing well. The GAGD process can be implemented as a secondary or tertiary oil recovery method. Several physical model experiments have been conducted to demonstrate the effectiveness of the GAGD process for …

Comparative Study Of One Parameter Budyko Model Index And The Scs Curve Number, Cihad Ayberk Doner

LSU Master's Theses

This study investigates two water balance models from different levels of complexity to recognize the impacts of climate change on water resources. The main objective is to examine the capacity of future runoff calculations of a parsimonious simple water balance model compared to a more complex model under the climate change variables. The selected water balance models are the simple one-parameter Budyko-type model using the Zhang’s equation with single parameter (a) and the more complex model (HELP3) applying Soil Conservation Service (SCS) curve number method to calculate future runoff predictions. The study has a twofold focus, first on explaining the …