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Full-Text Articles in Engineering
Generation Of Silver Nanoparticle Pharmacokinetic Profiles In A Lung Model, Rachel Galaska
Generation Of Silver Nanoparticle Pharmacokinetic Profiles In A Lung Model, Rachel Galaska
Honors Theses
Nanomaterial technologies are becoming increasingly prevalent in consumer and industrial applications, including drug delivery, energy harvesting, environmental applications, and medicine due to their unique physiochemical properties. As nanomaterial use increases, so too does human exposure. This has made it progressively more important to understand the toxicological effects of nanomaterials and their interactions with the human body. Silver nanoparticles (AgNPs) are one of the most commonly used nanomaterials due to their antibacterial properties. As inhalation is one of the most common exposure routes, understanding the toxicity of these AgNPs on lung tissue was studied. Using A549 cells for a lung tissue …
Effect Of Activated Carbon On The Performance Of A Solar Thermal Adsorptive Refrigerator (Star) Using Activated Carbon-Ethanol, Joshua Romo
Honors Theses
The Solar Thermal Adsorptive Refrigerator (STAR) project at the University of Dayton seeks to bridge sustainability and the need for reliable refrigeration in developing communities. Cost-effective construction, operation, and maintenance as well as the use of a sustainable adsorption pair, activated carbon-ethanol, give STAR great potential in the realm of humanitarian engineering. This project explores the effect of using two activated carbon brands, 8x16 and CocoPlus, on the cyclic performance of the STAR system. Although both brands have similar specifications given by the manufacturer, one (8x16) inhibited successful performance while the other (CocoPlus) enabled it. This project highlights both the …
The Impact Of A Dynamic Environment On Deposition And Cellular Response To Silver Nanoparticles, Robert F. Uhrig
The Impact Of A Dynamic Environment On Deposition And Cellular Response To Silver Nanoparticles, Robert F. Uhrig
Honors Theses
Silver nanoparticles (AgNPs) are utilized in many different applications, such as an antibacterial agents or as protective coating against ultraviolet light. However, these AgNPs are known to cause potentially harmful biological effects, including toxicity, induction of stress, and immune activation. In this study, the effects of AgNPs on a human lung cell model were examined within both a static and dynamic environment. Most NP-based research is carried out in static environments, but do not accurate reflect dynamic physiological conditions. Dynamic fluid movement was introduced to the cell culture through the use of a multi-channel peristaltic pump. To further characterize the …