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Articles 1 - 5 of 5
Full-Text Articles in Engineering
Experimental Investigation Of Stochastic Parafoil Guidance Using A Graphics Processing Unit, Nathan Slegers, Andrew Brown, Jonathan Rogers
Experimental Investigation Of Stochastic Parafoil Guidance Using A Graphics Processing Unit, Nathan Slegers, Andrew Brown, Jonathan Rogers
Faculty Publications - Biomedical, Mechanical, and Civil Engineering
Control of autonomous systems subject to stochastic uncertainty is a challenging task. In guided airdrop applications, random wind disturbances play a crucial role in determining landing accuracy and terrain avoidance. This paper describes a stochastic parafoil guidance system which couples uncertainty propagation with optimal control to protect against wind and parameter uncertainty in the presence of impact area obstacles. The algorithm uses real-time Monte Carlo simulation performed on a graphics processing unit (GPU) to evaluate robustness of candidate trajectories in terms of delivery accuracy, obstacle avoidance, and other considerations. Building upon prior theoretical developments, this paper explores performance of the …
Planning Rural Water Services In Nicaragua: A Systems-Based Analysis Of Impact Factors Using Graphical Modeling, Jeffrey P. Walters, Paul S. Chinowsky
Planning Rural Water Services In Nicaragua: A Systems-Based Analysis Of Impact Factors Using Graphical Modeling, Jeffrey P. Walters, Paul S. Chinowsky
Faculty Publications - Biomedical, Mechanical, and Civil Engineering
The success or failure of rural water services in the developing world is a result of numerous factors that interact in a complex set of connections that are difficult to separate and identify. This research effort presented a novel means to empirically reveal the systemic interactions of factors that influence rural water service sustainability in the municipalities of Darío and Terrabona, Nicaragua. To accomplish this, the study employed graphical modeling to build and analyze factor networks. Influential factors were first identified by qualitatively and quantitatively analyzing transcribed interviews from community water committee members. Factor influences were then inferred by graphical …
Long-Term Functionality Of Rural Water Services In Developing Countries: A System Dynamics Approach To Understanding The Dynamic Interaction Of Causal Factors, Jeffrey P. Walters, Amy N. Javernick-Will
Long-Term Functionality Of Rural Water Services In Developing Countries: A System Dynamics Approach To Understanding The Dynamic Interaction Of Causal Factors, Jeffrey P. Walters, Amy N. Javernick-Will
Faculty Publications - Biomedical, Mechanical, and Civil Engineering
Research has shown that sustainability of rural water infrastructure in developing countries is largely affected by the dynamic and systemic interactions of technical, social, financial, institutional, and environmental factors that can lead to premature water system failure. This research employs systems dynamic modeling, which uses feedback mechanisms to understand how these factors interact dynamically to influence long-term rural water system functionality. To do this, the research first identified and aggregated key factors from literature, then asked water sector experts to indicate the polarity and strength between factors through Delphi and cross impact survey questionnaires, and finally used system dynamics modeling …
Management Of Rural Water Services In Nicaragua: A Systematic Network Approach To Evaluating Stakeholder Alignment, Jeffrey P. Walters, Amy N. Javemick-Will
Management Of Rural Water Services In Nicaragua: A Systematic Network Approach To Evaluating Stakeholder Alignment, Jeffrey P. Walters, Amy N. Javemick-Will
Faculty Publications - Biomedical, Mechanical, and Civil Engineering
Water sector literature attributes a substantial cause of rural water system failure in developing countries to poor alignment between water service stakeholders. This study aimed to investigate a means for assessing stakeholder alignment by comparing the systemic interaction of stakeholder values, where the term ‘stakeholder values’ refers to aspects stakeholders believe are necessary to ensure rural water services are sustainable. The research held focus groups with key stakeholder groups involved in the management of rural water infrastructure in Terrabona, Nicaragua, to identify stakeholder values, and then used cross-impact analysis to evaluate how these values interacted to form stakeholder value networks …
Liver Sinusoid On A Chip: Long-Term Layered Co-Culture Of Primary Rat Hepatocytes And Endothelial Cells In Microfluidic Platforms, Young Bok (Abraham) Kang, Temitope R. Sodunke, Jason Lamontagne, Joseph Cirillo, Caroline Rajiv, Michael J. Bouchard, Moses Noh
Liver Sinusoid On A Chip: Long-Term Layered Co-Culture Of Primary Rat Hepatocytes And Endothelial Cells In Microfluidic Platforms, Young Bok (Abraham) Kang, Temitope R. Sodunke, Jason Lamontagne, Joseph Cirillo, Caroline Rajiv, Michael J. Bouchard, Moses Noh
Faculty Publications - Biomedical, Mechanical, and Civil Engineering
We describe the generation of microfluidic platforms for the co-culture of primary hepatocytes and endothelial cells; these platforms mimic the architecture of a liver sinusoid. This paper describes a progressional study of creating such a liver sinusoid on a chip system. Primary rat hepatocytes (PRHs) were co-cultured with primary or established endothelial cells in layers in single and dual microchannel configurations with or without continuous perfusion. Cell viability and maintenance of hepatocyte functions were monitored and compared for diverse experimental conditions. When primary rat hepatocytes were co-cultured with immortalized bovine aortic endothelial cells (BAECs) in a dual microchannel with continuous …