Engineering Commons^™

Structural And Hemodynamic Analysis Of Transcatheter Aortic Valves, Dong Qiu

Electronic Theses and Dissertations

The transcatheter aortic valve replacement (TAVR) procedure has become a well-established procedure for high, intermediate-risk, and low-risk patients. However, there is limited clinical data on the TAV's long-term durability, unlike SAV devices. Computational simulations can be an alternative way to evaluate the TAV devices. This dissertation aims to conduct structural and hemodynamic analyses on the TAV devices under different conditions using computational simulation approaches.

Initially, the impact of the bicuspid aortic valve on the TAV devices was evaluated. The result indicated that the CoreValve-like supra-annular self-expandable device was likely to have increased stress and strain on the leaflet when it …

A Computational Fluid Dynamics Analysis Of The Temperature And Impurity Profiles In The Protodune-Sp Neutrino Detector, Jenna Harrison

Electronic Theses and Dissertations

Computational fluid dynamics (CFD) models of the ProtoDUNE single-phase detector were developed, refined, and analyzed. The ProtoDUNE single-phase detector is a prototype detector that is part of the Deep Underground Neutrino Experiment, an international research collaboration aimed at better understanding neutrinos and the role they play in our universe. The ProtoDUNE single-phase detector is used to gather data and inform design changes for the full-sized far detector prior to its construction. The effects of certain geometric features and heat sources on the thermal profiles within the liquid region of the detector were investigated in a set of parametric studies. The …