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Full-Text Articles in Engineering

Fabrication And Application Of Conducting Polymer Micro- And Nano-Patterns, Anirban Chakraborty Jul 2007

Fabrication And Application Of Conducting Polymer Micro- And Nano-Patterns, Anirban Chakraborty

Doctoral Dissertations

Conducting polymers, since their discovery, have attracted significant attention due to their promise of replacing silicon and metals in building devices. They have been shown to have wide applications for biological and chemical sensing as well as for electronic devices. Previous and current efforts have concentrated on building devices of a specific function. When multiple micropatterns of different conducting polymers are fabricated on a common substrate, a versatile microsystem can be envisioned. The existing conducting polymer patterning techniques present some technical challenges of degradation, low throughput, low resolution, depth of field, and residual layer in producing conducting polymer microstructures. To …


Growth And Behavior Of Chondrocytes On Nano Engineered Surfaces And Construction Of Micropatterned Co-Culture Platforms Using Layer-By-Layer Platforms Using Layer -By -Layer Assembly Lift-Off Method, Jameel Shaik Apr 2007

Growth And Behavior Of Chondrocytes On Nano Engineered Surfaces And Construction Of Micropatterned Co-Culture Platforms Using Layer-By-Layer Platforms Using Layer -By -Layer Assembly Lift-Off Method, Jameel Shaik

Doctoral Dissertations

Several approaches such as self-assembled monolayers and layer-by-layer assembled multilayer films are being used as tools to study the interactions of cells with biomaterials in vitro. In this study, the layer-by-layer assembly approach was used to create monolayer, bilayer, trilayer, five, ten and twenty-bilayer beds of eleven different biomaterials. The various biomaterials used were poly(styrene-sulfonate), fibronectin, poly-L-lysine, poly-D-lysine, laminin, bovine serum albumin, chondroitin sulfate, poly(ethyleneimine), polyethylene glycol amine, collagen and poly(dimethyldiallyl-ammonium chloride) with unmodified tissue-culture polystyrene as standard control. Three different cell lines—primary bovine articular chondrocytes, and two secondary cell lines, human chondrosarcoma cells and canine chondrocytes were used in …