Engineering Commons^™

Electrolytic Metallization Of Halloysite Nanotubes And Antimicrobial Applications, Ahmed Humayun

Doctoral Dissertations

Due to increased reports of infections and biofouling arising from the use of invasive medical devices, novel antimicrobial agents with suitable anti-biofouling properties are critically needed. Transition metals exhibit substantial antimicrobial activity; however, their use is limited because of their inherent toxicity to eukaryotic cells. In this regard, naturally occurring halloysite clay nanotubes (HNTs) show significant promise. HNTs possess a high surface area for adsorption while its hollow lumen can be used for loading different materials.

Herein, we demonstrate an electrolytic method for generating and depositing metal nanoparticles (NPs) on the HNTs outer surface and we propose an optimized method …

Application Of Halloysite Nanotubes In Bone Disease Remediation And Bone Regeneration, Yangyang Luo

Doctoral Dissertations

Customized patient therapy has been a major research focus in recent years. There are two research fields that have made a significant contribution to realizing individualized-based treatment: targeted drug delivery and three-dimensional (3D) printing technology. With benefit from the advances in nanotechnology and biomaterial science, various drug delivery systems have been established to provide precise control of therapeutic agents release in time and space. The emergence of three-dimensional (3D) printing technology enables the fabrication of complicated structures that effectively mimic native tissues and makes it possible to print patient-specific implants. My dissertation research used a clay nanoparticle, halloysite, to develop …