Engineering Commons^™

Effects Of Scattering And Absorption On Laser Speckle Contrast Imaging, Kosar Khaksari

Dissertations, Master's Theses and Master's Reports

Laser Speckle Contrast Imaging (LSCI) is a real-time, non-invasive method in used to investigate blood flow and perfusion in biological tissues with high temporal and spatial resolution. A reduction in speckle contrast due to particle motion is the primary contrast mechanism in LSCI. Motion results in speckle fluctuations in time and reduces the contrast over a given camera integration period. There are a variety of parameters that effect contrast besides motion. The optical properties of the scattering medium are one of the parameters effecting LSCI values. Changes in blood hematocrit levels manifest as changes in optical properties. In this work, …

Hardware Design And Integration And Software Programming For Optical Elastography, Nima Taherkhani

Dissertations, Master's Theses and Master's Reports

The elastic and viscoelastic properties of skin are a reflection of its health. Measurement of these elastic properties can be used as the indicator of various pathologies. The measurement concept in our works is to mechanically stimulate the skin with a low frequency pneumatic force using non-invasive means of deflecting the skin and use laser speckle to study the elasticity of the skin.

The goal of this work was to develop a setup for in vivo optical elastography of skin. This setup includes an electro-mechanical device which is able to deliver a sinusoidal pneumatic stimulus equivalent to 10 grams of …