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Department of Biomedical, Industrial & Human Factors Engineering

2022

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Development Of Gene Regulatory Elements For Biosensing Applications, Mallory N. Bates Jan 2022

Development Of Gene Regulatory Elements For Biosensing Applications, Mallory N. Bates

Browse all Theses and Dissertations

21% of U.S adults experienced mental illnesses in 2020. Nearly 1 in 4 active- duty military personnel showed signs of mental health conditions in 2014 [89]. Mental health can be identified in the body by different biomarkers. These biomarkers potentially could be controlled by riboswitches, which could help mental illnesses and regulate diseases. Riboswitches are desirable in these cases due to responding without affecting vital functions. Riboswitches are located in mRNA and switch “ON” or “OFF” depending on the concentration of a biomarker [13]. In this research, riboswitches were re-engineered to take a known riboswitch and control its response in …