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Full-Text Articles in Engineering
Single-Pixel Camera Based Spatial Frequency Domain Imaging For Non-Contact Tissue Characterization, Alec M. Petrack
Single-Pixel Camera Based Spatial Frequency Domain Imaging For Non-Contact Tissue Characterization, Alec M. Petrack
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Optical imaging has demonstrated potential as a medical imaging modality for measuring tissue functionality. Recently, interest in fluorescence guided surgery has emerged from improvements in optical imaging that have allowed real-time feedback. Of the optical imaging modalities, spatial frequency domain imaging (SFDI) has gained a lot of interest. Unlike spectroscopic techniques, such as functional near infrared spectroscopy (fNIRS) and frequency domain spectroscopy that measure bulk tissue properties, SFDI quantifies tissue functionality locally and wide field making it practical for clinical applications. Unfortunately, traditional SFDI systems use multi-pixel detectors, which may not exhibit ideal spectral characteristics, have limited sensitivity, be expensive, …
Global Joint Registry: Analysis Of Revision Hip Arthroplasty Data, Alicia M. Runser
Global Joint Registry: Analysis Of Revision Hip Arthroplasty Data, Alicia M. Runser
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Total hip arthroplasty (THA) has become well-known as being one of the most successful procedures with much long-term positive clinical results. However, revision surgeries are still required. The four most common failure modes for THAs, “reasons for revision”, are loosening, dislocation or instability, fracture, and infection. The goal of a hip arthroplasty register is to gather information on patients that undergo a total hip arthroplasty and factors pertaining to their surgery which may affect their outcome for future years such as the reason for revision. Analysis of this data can help with the allocation of healthcare funds and the efficacy …
Observing P300 Amplitudes In Multiple Sensory Channels Using Cognitive Probing, Cody Lee Wintermute
Observing P300 Amplitudes In Multiple Sensory Channels Using Cognitive Probing, Cody Lee Wintermute
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High cognitive workload occurs when excessive working memory resources have been deployed to resolve sensory and cognitive processing, resulting in decremented task performance. The P300 event-related potential (ERP) component has shown sensitivity to cognitive load, and it was hypothesized that an attenuated P300 amplitude could be indicative of high cognitive load. We tested this hypothesis by having eight participants complete two continual performance tasks at increasing workload levels while simultaneously performing an oddball task, evoking P300 ERPs in either the auditory or tactile sensory channel. In our experiment, electroencephalographic recordings were collected over the parietal region to observe the P300 …
Kv2.1 Channel Clustering In The Sod1-G93a Mouse Model Of Als, Joshua Christopher Harris
Kv2.1 Channel Clustering In The Sod1-G93a Mouse Model Of Als, Joshua Christopher Harris
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Kv2.1 channels mediate slow-activating K+ rectifier current within the membrane of spinal motoneurons (MNs), and they are known to co-localize with other synapses and ion channels. Although Kv2.1 channels are suggested to regulate MN excitability, little research has gone into investigating its potential contribution to MN-altered excitability in Amyotrophic Lateral Sclerosis (ALS). Using the male SOD1-G93A mouse model of ALS, we examined Kv2.1 cluster area and density in lumbar MNs at four key stages of disease progression. In our experiments, MNs were separated by type via SK3 immunoreactivity in order to isolate and compare the responses of disease-resistant (slow; SK3+) …
Eye-Tracking To Evaluate Trust In Human-Atr Interaction, Samuel Francis Adelman
Eye-Tracking To Evaluate Trust In Human-Atr Interaction, Samuel Francis Adelman
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Human collaboration with targeting aids have allowed analysts to achieve a greater level of coordination and productivity in a variety of fields. This project investigates the impact that an Assisted Target Recognition (ATR) algorithm’s false alarm rate and the task Target of Interest (TOI) level has on user-system trust and use in a targeting decision task. Previous studies suggest that an increased number of false alarms in an ATR task negatively impacts analyst trust in the system. This study will further contribute to this research, aiming to provide a better framework for appropriate tolerance levels within ATR algorithms, utilizing pre-truthed …
An Approach To Cluster And Benchmark Regional Emergency Medical Service Agencies, Swetha Kondapalli
An Approach To Cluster And Benchmark Regional Emergency Medical Service Agencies, Swetha Kondapalli
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Emergency Medical Service (EMS) providers are the first responders for an injured patient on the field. Their assessment of patient injuries and determination of an appropriate hospital play a critical role in patient outcomes. A majority of states in the US have established a state-level governing body (e.g., EMS Division) that is responsible for developing and maintaining a robust EMS system throughout the state. Such divisions develop standards, accredit EMS agencies, oversee the trauma system, and support new initiatives through grants and training. But to do so, these divisions require data to enable them to first understand the similarities between …
Visual Sampling With The Eeg Alpha Oscillation, Kevin Eugene Alexander
Visual Sampling With The Eeg Alpha Oscillation, Kevin Eugene Alexander
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The posterior alpha rhythm, seen in human electroencephalograms (EEG), is posited to originate from cycling inhibitory/excitatory states of visual relay cells in the thalamus, which could result in discrete sampling of visual information. Here, we tested this hypothesis by presenting light flashes at perceptual threshold intensity through closed eyelids to 20 participants during times of spontaneous alpha oscillations. Alpha phase and amplitude were calculated relative to each individual’s retina-to-V1 conduction delay, estimated by the individuals’ C1 visual-evoked potential latency. Our results show that an additional 20.96% of stimuli are observed when afferenting at V1 during an alpha wave trough (272.41°) …
Understanding Visual Representation Of Imputed Data For Aiding Human Decision-Making, Ryan M. Thompson
Understanding Visual Representation Of Imputed Data For Aiding Human Decision-Making, Ryan M. Thompson
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The effectiveness of representing higher dimensional data on a two-dimensional visualization was required to be studied in the development of a novel data imputation method, Continuous Imputation With Association Rules (CIWAR). When the CIWAR method is used to impute missing data, the method generates additional metadata that increases each imputed data point's dimensionality. Potential use cases for CIWAR include situations where imputed data would be analyzed by individuals with little or no data analytic experience or situations where imputed data would be used to aid high-stress time-critical human decision processes. A study was conducted to assess the effect of the …