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Full-Text Articles in Engineering

Evaluating Tissue Morphology In The Context Of Varied Initial Fabrication Conditions, Cassidy Caffin May 2024

Evaluating Tissue Morphology In The Context Of Varied Initial Fabrication Conditions, Cassidy Caffin

Biomedical Engineering Undergraduate Honors Theses

Cardiovascular diseases have been the leading cause of death for years. This includes myocardial infarctions (MI) where blood flow to the myocardium is restricted. This causes damage to cardiac muscle due to insufficient oxygen. There are multiple ways to treat patients following an MI with the most common involving assorted medication. However, there are limited medications that can be used for treating patients following MIs, and the FDA’s decreasing approval rate for new cardiac drugs will not dramatically improve the range of options. The lead-up to drug candidate rejection by the FDA can involve drugs exhibiting promising preliminary research that …


Dorsal Root Ganglia Neurite Outgrowth Following Traumatic Spinal Cord Injury Repair: A Review, Adrienne Vaughan May 2024

Dorsal Root Ganglia Neurite Outgrowth Following Traumatic Spinal Cord Injury Repair: A Review, Adrienne Vaughan

Biomedical Engineering Undergraduate Honors Theses

Traumatic spinal cord injury (tSCI) can cause partial sensorimotor deficiency or total dysfunction, rendering patients unable to perform necessary tasks and dramatically decreasing their quality of life. tSCI is a very prevalent issue. In the United States alone, there are approximately 54 new cases of SCI per one million people each year, or 18,000 new cases annually. tSCI creates a lesion gap filled with axon-inhibiting fibrotic scar tissue. Comprehensive functional recovery following traumatic spinal cord injury (tSCI) requires axonal regeneration across wound site lesions. Dorsal root ganglia (DRG) neurite outgrowth is often evaluated in PNI therapeutic research since it can …


Analyzing Diverse Student Experiences: The Intersection Of Equity, Inclusivity, And Biomedical Engineering Education Through A Clinical Observations And Needs Finding Course, Jacquelynn Horsey May 2024

Analyzing Diverse Student Experiences: The Intersection Of Equity, Inclusivity, And Biomedical Engineering Education Through A Clinical Observations And Needs Finding Course, Jacquelynn Horsey

Biomedical Engineering Undergraduate Honors Theses

In the field of biomedical engineering, needs identification and solution development are an important element of the design process. In our undergraduate curriculum, a course was designed to allow clinical observation and provide an opportunity for students to learn about engineering design and engage with clinicians via completing rotations in medical facilities near our campus. While this type of course is not unique, evaluating its efficacy is not simple. Given the broad range of institutional resources available- such as proximity to a medical school, or residency programs- reporting the quality of such courses within the context of such available resources …