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Articles 1 - 9 of 9
Full-Text Articles in Engineering
An Investigation Of Process Parameters To Optimize The Fiber Diameter Of Electrospun Vascular Scaffolds Through Experimental Design, Steffi Wong
Biomedical Engineering
No abstract provided.
Characterization And Analysis Techniques Of A Dynamic In Vitro Blood-Brain Barrier Model, Ryan Everett Woodhouse
Characterization And Analysis Techniques Of A Dynamic In Vitro Blood-Brain Barrier Model, Ryan Everett Woodhouse
Biomedical Engineering
The blood-brain barrier (BBB) is responsible for maintaining the sensitive environment required by the brain. Although the BBB is necessary for proper functioning of the brain, it acts as an obstacle for doctors attempting to treat neurological disease. For a drug to act upon the brain, it must first pass through the discriminating BBB. For this reason, much research has been performed in recent years in order to create an in vitro model of the BBB on which drugs targeted for the central nervous system may be tested. The main goal of this project is to create an in vitro …
Can Spr Be Used To Interrogate The Double Layer Of Nacl, Brandon Kawula
Can Spr Be Used To Interrogate The Double Layer Of Nacl, Brandon Kawula
Biomedical Engineering
Solutions of reagent grade salt .1, .01, .001, .0001, .00001M were run through a SPR to see if SPR had enough resolution to detect the formation of the electric double layer. We found that NaCl did in fact return a detectable signal. The signal shape seems to depend on concentration. While more study may need to be done to get definite information it looks like SPR can interrogate the double layer.
Motorcycle Data Acquisition System, Jonathan Luke Harmse
Motorcycle Data Acquisition System, Jonathan Luke Harmse
Biomedical Engineering
No abstract provided.
Immunohistochemical Mapping Of Hypoxia In Ischemic Mouse Hindlimb Skeletal Muscle, Emily Deckert
Immunohistochemical Mapping Of Hypoxia In Ischemic Mouse Hindlimb Skeletal Muscle, Emily Deckert
Biomedical Engineering
The study of blood vessel growth and remodeling is a complex endeavor. Hypoxia, the lack of oxygen in a tissue, is known to stimulate angiogenesis (the growth of new blood vessels), and have little effect on arteriogenesis (the enlargement of existing blood vessels). However, the role of hypoxia in vessel function is unknown, but may be determined using the results and methods developed in this experiment.
Supplied by the bloodstream, oxygen is required by all cells and tissues to remain healthy. If the bloodstream supplying a certain tissue with blood is disrupted, the tissue becomes ischemic, often leading to hypoxia. …
Aircraft Data Collection System, Amy Kronsteiner, Danny Marx, Collin Heller, Nathaniel Garcia, Nicholas Riccobono, Scott Parks, Albert Liu
Aircraft Data Collection System, Amy Kronsteiner, Danny Marx, Collin Heller, Nathaniel Garcia, Nicholas Riccobono, Scott Parks, Albert Liu
Biomedical Engineering
This report outlines the design and building process for an interchangeable testing device that collects aircraft performance data. Included is the project objectives, system requirements, management plan, design concept development, design details, manufacturing procedures, and project verification test plans. The device is a wing-mounted Pitot-static system integrated with an Electronic Flight Instrument System (EFIS).
Development Towards A Protocol To Test For The Creation Of A “Diabetic” Environment In A Blood Vessel Mimic, Kaitlyn Kirk, Development Towards A Protocol To Test For The Creation Of A “Diabetic” Environment In A Blood Vessel Mimic
Development Towards A Protocol To Test For The Creation Of A “Diabetic” Environment In A Blood Vessel Mimic, Kaitlyn Kirk, Development Towards A Protocol To Test For The Creation Of A “Diabetic” Environment In A Blood Vessel Mimic
Biomedical Engineering
Diabetes mellitus affects a huge proportion of people; about 6% of the population in the US had diabetes in 2007 (16). Diabetes promotes dyslipidemia, an imbalance in the circulating levels of lipids and lipoproteins, and diabetes is one of the leading risk factors for coronary artery and peripheral vascular diseases (11, 51, 52). There are two types of diabetes; type 1 diabetes accounts for about 10% of diagnosed cases and type 2 accounts for about 90% (11). Diabetic patients react differently to stents and there is a great need to enhance the treatment. The goal of this project was, and …
A Sustainable Business Proposition For Selling Irrigation Pumps In Ndola, Zambia, Robert Hosbach
A Sustainable Business Proposition For Selling Irrigation Pumps In Ndola, Zambia, Robert Hosbach
Biomedical Engineering
Robert Hosbach is proposing a sustainable business plan to bring a small‐scale irrigation pump to rural Ndola, Zambia. With hundreds of thousands of citizens living in poverty and semi‐annual starvation, Ndola is in need of a means to grow crops effectively in the rainy season. Their current agricultural practices rely solely on the inconsistent rainfall during this time. My pump will be constructed from locally‐available aluminum cans, epoxy, glue, and fasteners (refer to Appendix B for technical drawings of the pump). The business will employ only a small number of Zambians, but will bring a means of food and income …
Impaired Vascular Reactivity Following Chronic Ischemia In The Arteries Of The Mouse Hindlimb, Thomas (Tom) Kesler
Impaired Vascular Reactivity Following Chronic Ischemia In The Arteries Of The Mouse Hindlimb, Thomas (Tom) Kesler
Biomedical Engineering
Collateral dependent hyperemia is reduced following chronic ischemia, but the contribution of individual vessel reactivity is unknown. Further, it is not known what aspect of the complex ischemic injury response impacts vascular reactivity. To determine the impact of ischemia on vascular reactivity, we measured functional vasodilation in the muscular branch artery following resection of the femoral artery proximal to the muscular branch. On day-14 after surgery the diameter of the muscular branch was measured using side-stream dark field (SDF) imaging intravital microscopy. At moderate intensity skeletal muscle contraction (1mA, 200µs, 8Hz, 90sec), functional vasodilation is reduced compared to the contralateral …