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Full-Text Articles in Engineering
Injectable Phenytoin Loaded Polymeric Microspheres For The Control Of Temporal Lobe Epilepsy In Rats, Jonathan Jiang, Zhilian Yue, Sebastien Bauquier, Alan Lai, Yu Chen, Karen J. Mclean, Amy J. Halliday, Yi Sui, Simon E. Moulton, Gordon G. Wallace, Mark J. Cook
Injectable Phenytoin Loaded Polymeric Microspheres For The Control Of Temporal Lobe Epilepsy In Rats, Jonathan Jiang, Zhilian Yue, Sebastien Bauquier, Alan Lai, Yu Chen, Karen J. Mclean, Amy J. Halliday, Yi Sui, Simon E. Moulton, Gordon G. Wallace, Mark J. Cook
Australian Institute for Innovative Materials - Papers
Epilepsy is a prevalent neurological disorder with a high frequency of drug resistance. While significant advancements have been made in drug delivery systems to overcome anti-epileptic drug resistance, efficacies of materials in biological systems have been poorly studied. The purpose of the study was to evaluate the anti-epileptic effects of injectable poly(epsiloncaprolactone) (PCL) microspheres for controlled release of an anticonvulsant, phenytoin (PHT), in an animal model of epilepsy. Methods: PHT-PCL and Blank-PCL microspheres formulated using an oil-in-water (O/W) emulsion solvent evaporation method were evaluated for particle size, encapsulation efficiency, surface morphology and in-vitro drug release profile. Microspheres with the most …
Force Control Of A Tri-Layer Conducting Polymer Actuator Using Optimized Fuzzy Logic Control, Mehmet Itik, Mohammadreza Sabetghadam, Gursel Alici
Force Control Of A Tri-Layer Conducting Polymer Actuator Using Optimized Fuzzy Logic Control, Mehmet Itik, Mohammadreza Sabetghadam, Gursel Alici
Australian Institute for Innovative Materials - Papers
Conducting polymers actuators (CPAs) are potential candidates for replacing conventional actuators in various fields, such as robotics and biomedical engineering, due to their advantageous properties, which includes their low cost, light weight, low actuation voltage and biocompatibility. As these actuators are very suitable for use in micro-nano manipulation and in injection devices in which the magnitude of the force applied to the target is of crucial importance, the force generated by CPAs needs to be accurately controlled. In this paper, a fuzzy logic (FL) controller with a Mamdani inference system is designed to control the blocking force of a trilayer …
Liquid Ink Deposition From An Atomic Force Microscope Tip: Deposition Monitoring And Control Of Feature Size, Cathal D. O'Connell, Michael J. Higgins, David Marusic, Simon E. Moulton, Gordon G. Wallace
Liquid Ink Deposition From An Atomic Force Microscope Tip: Deposition Monitoring And Control Of Feature Size, Cathal D. O'Connell, Michael J. Higgins, David Marusic, Simon E. Moulton, Gordon G. Wallace
Australian Institute for Innovative Materials - Papers
The controlled deposition of attoliter volumes of liquid inks may engender novel applications such as targeted drug delivery to single cells and localized delivery of chemical reagents at nanoscale dimensions. Although the deposition of small organic molecules from an atomic force microscope tip, known as dip-pen nanolithography (DPN), has been extensively studied, the deposition of liquid inks is little understood. In this work, we have used a set of model ink-substrate systems to develop an understanding of the deposition of viscous liquids using an unmodified AFM tip. First, the growth of dot size with increasing dwell time is characterized. The …
Single-Pulse Terahertz Coherent Control Of Spin Resonance In The Canted Antiferromagnet Yfeo3, Mediated By Dielectric Anisotropy, Zuanming Jin, Zoltan Mics, Guohong Ma, Zhenxiang Cheng, Mischa Bonn, Dmitry Turchinovich
Single-Pulse Terahertz Coherent Control Of Spin Resonance In The Canted Antiferromagnet Yfeo3, Mediated By Dielectric Anisotropy, Zuanming Jin, Zoltan Mics, Guohong Ma, Zhenxiang Cheng, Mischa Bonn, Dmitry Turchinovich
Australian Institute for Innovative Materials - Papers
We report on the coherent control of terahertz (THz) spin waves in a canted antiferromagnet yttrium orthoferrite, YFeO3, associated with a quasiferromagnetic (quasi-FM) spin resonance at a frequency of 0.3 THz, using a single-incident THz pulse. The spin resonance is excited impulsively by the magnetic field component of the THz pulse. The intrinsic dielectric anisotropy of YFeO3 in the THz range allows for coherent control of both the amplitude and the phase of the excited spin wave. The coherent control is based on simultaneous generation of two interfering phase-shifted spin waves whose amplitudes and relative phase, dictated by the dielectric …
Reaction Method Control Of Impurity Scattering In C-Doped Mgb2: Proving The Role Of Defects Besides C Substitution Level, S K. Chen, K Y. Tan, A S. Halim, X Xu, K S. B De Silva, W K. Yeoh, S X. Dou, A Kursumovic, J L. Macmanus-Driscoll
Reaction Method Control Of Impurity Scattering In C-Doped Mgb2: Proving The Role Of Defects Besides C Substitution Level, S K. Chen, K Y. Tan, A S. Halim, X Xu, K S. B De Silva, W K. Yeoh, S X. Dou, A Kursumovic, J L. Macmanus-Driscoll
Australian Institute for Innovative Materials - Papers
In this study, Si and C were incorporated into polycrystalline MgB2 via in situ reaction of Mg and B with either SiC or with separate Si and C (Si+C). The electrical transport and magnetic properties of the two series of samples were compared. The corrected resistivity at 40K, pA(40K), is higher for the SiC reacted samples regardless of carbon (C) substitution level, indicating larger intragrain scattering because of the simultaneous reaction between Mg and SiC and carbon substitution during the formation of MgB2. In addition, because of the cleaner reaction route for the SiC reacted samples, the calculated active area …
In Situ Growth Of Nanoparticles Through Control Of Non-Stoichiometry, Dragos Neagu, George Tsekouras, David N. Miller, Herve Menard, John T. S Irvine
In Situ Growth Of Nanoparticles Through Control Of Non-Stoichiometry, Dragos Neagu, George Tsekouras, David N. Miller, Herve Menard, John T. S Irvine
Australian Institute for Innovative Materials - Papers
Surfaces decorated with uniformly dispersed catalytically active nanoparticles play a key role in many fields, including renewable energy and catalysis. Typically, these structures are prepared by deposition techniques, but alternatively they could be made by growing the nanoparticles in situ directly from the (porous) backbone support. Here we demonstrate that growing nano-size phases from perovskites can be controlled through judicious choice of composition, particularly by tuning deviations from the ideal ABO3 stoichiometry. This non-stoichiometry facilitates a change in equilibrium position to make particle exsolution much more dynamic, enabling the preparation of compositionally diverse nanoparticles (that is, metallic, oxides or …
Control Of Biodegradation Of A Mg Alloy In Simulated Body Fluid, Yafei Zhang, Maria Forsyth, Bruce Hinton, Gordon G. Wallace
Control Of Biodegradation Of A Mg Alloy In Simulated Body Fluid, Yafei Zhang, Maria Forsyth, Bruce Hinton, Gordon G. Wallace
Australian Institute for Innovative Materials - Papers
Mg alloy AZ31 is an attractive candidate for coronary artery stents, as it possesses excellent biocompatibility in human body and good mechanical properties. However, AZ31 magnesium alloys generally have poor corrosion resistance in the body environment. This paper reports on the early stages of an investigation into the corrosion mechanism and the morphology of corrosion of AZ31 in simulated body fluid (SBF), The investigation will also consider ways of improving corrosion resistance of this alloy in SBF through the use of ionic liquids. The results to date have shown that AZ31 suffers severe localized pitting corrosion in SBF. The pits …
The Control Of Time-Dependent Buckling Patterns In Thin Confined Elastomer Film, Brad Winton, Mihail Ionescu, S X. Dou
The Control Of Time-Dependent Buckling Patterns In Thin Confined Elastomer Film, Brad Winton, Mihail Ionescu, S X. Dou
Australian Institute for Innovative Materials - Papers
Low energy metal ion implantation has been used to combine an easy “bottom-up” way of creating and tuning different topographic structures on submicron to micrometer scales with the embedding of a metallic element-rich functionalized layer at the surface for a variety of scientific and technological applications. The self-organizing and complex patterns of functionalized topographic structures are highly dependent on the implanted metal ion species, variations in the geometric confinement of the buckled areas on the larger unmodified elastomer film, and the boundary conditions of the buckled regions. Systematic investigations of these dependencies have been carried out via optical and atomic …