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Full-Text Articles in Engineering
Preliminary Investigation Into The Design Of Thermally Responsive Forster Resonance Energy Transfer Colloids, Monte Bedford
Preliminary Investigation Into The Design Of Thermally Responsive Forster Resonance Energy Transfer Colloids, Monte Bedford
All Theses
While nuclear imaging techniques (Magnetic Resonance Imaging, Computed Tomography, and Positron Emission Tomography) have proven effective for diagnosis and treatment of disease in the human body, fluorescence-enhanced optical imaging offers additional benefits. Fluorescent imaging provides high resolution with real-time response, persistent lifetime (hours to days), cell targeting, and transdermal penetration with minimal physical encumbrance. Malignant cells can be targeted by absorbance of exogenous fluorescent nanoprobe contrast agents. Imaging is improved by fluorescent enhancement, especially by energy transfer between attached dyes. Also for use against cancer are heat-active treatments, such as hyperthermal, photothermal, and chemothermal therapies. Helpful to these treatments is …
Measuring Ligand Exchange On The Surface Of Gold Nanoparticles: A Study Of Competitive Binding Of Ligands Utilizing Fluorescent Resonance Energy Transfer, Daniel D'Unger
All Theses
This study was conducted to track ligand exchange on the surface of metallic nanoparticles in order obtain a better understanding of binding strength of various functional groups. This study develops groundwork for further understanding ligand exchange as nanoparticles transition from engineered to natural systems. A problem exists in knowing the fate of these particles if they are released into natural systems, by accident or with intent. To gain a better understanding of what may occur we look at the binding strength of different ligands. This is done to gain knowledge of the possibility of displacement of ligands occurring in the …