Engineering Commons^™

A Deterministic Model Of The Effect Of Electric Field On Chemotherapeutics Delivery Into A Tumor, Maryam Moarefian, Luke Achenie

Biology and Medicine Through Mathematics Conference

No abstract provided.

Laser-Induced Breakdown Spectroscopy (Libs) In A Novel Molten Salt Aerosol System, Ammon N. Williams, Supathorn Phongikaroon

Mechanical and Nuclear Engineering Publications

In the pyrochemical separation of used nuclear fuel (UNF), fission product, rare earth, and actinide chlorides accumulate in the molten salt electrolyte over time. Measuring this salt composition in near real-time is advantageous for operational efficiency, material accountability, and nuclear safeguards. Laser-induced breakdown spectroscopy (LIBS) has been proposed and demonstrated as a potential analytical approach for molten LiCl–KCl salts. However, all the studies conducted to date have used a static surface approach which can lead to issues with splashing, low repeatability, and poor sample homogeneity. In this initial study, a novel molten salt aerosol approach has been developed and explored …

Effects Of Roughness On Droplet Apparent Contact Angles On A Fiber, M. M. Amrei, M. Davoudi, G. G. Chase, H. Vahedi Tafreshi

Mechanical and Nuclear Engineering Publications

This paper reports on our investigation of the effects of surface roughness on the equilibrium shape and apparent contact angles of a droplet deposited on a fiber. In particular, the shape of a droplet on a roughened fiber is studied via the energy minimization method implemented in the surface evolver finite element code. Sinusoidal roughness varying in both the longitudinal and radial directions is considered in the simulations to study the effects of surface roughness on the most stable shape of a droplet on a fiber (corresponding a global minimum energy state). It is found that surface roughness delays droplet …

In Defense Of Science—What Would John Do?, Mohamed Gad-El-Hak

Mechanical and Nuclear Engineering Publications

Recent onslaughts on the importance of pure research to our collective well-being are trending. In this essay, I discuss the issues involved and offer a rebuttal. The thoughts are inspired by my mentor, academic sibling, and idol John Leask Lumley.

A Silk Fibroin Hydrogel With Reversible Sol–Gel Transition, Zhuping Yin, Feng Wu, Tieling Xing, Vamsi K. Yadavalli, Subhas C. Kundu, Shenzhou Lu

Chemical and Life Science Engineering Publications

In this report, a novel silk fibroin hydrogel with a reversible sol-gel transition capacity is presented, in which the base material of this reversible hydrogel is hydrophilic silk fibroin (HSF) obtained by immersing a dried regenerated Bombyx mori silk fibroin (SF) condensate in deionized water (DI water) and collecting its lixivium. The resulting HSF sol can exhibit an enhanced sol-gel transition within several hours at suitable temperatures (25-50 degrees C) without any exterior additive, even at extremely low concentrations (

An Annotated Corpus With Nanomedicine And Pharmacokinetic Parameters, Nastassja Lewinski, Ivan Jimenez, Bridget Mcinnes

Chemical and Life Science Engineering Publications

A vast amount of data on nanomedicines is being generated and published, and natural language processing (NLP) approaches can automate the extraction of unstructured text-based data. Annotated corpora are a key resource for NLP and information extraction methods which employ machine learning. Although corpora are available for pharmaceuticals, resources for nanomedicines and nanotechnology are still limited. To foster nanotechnology text mining (NanoNLP) efforts, we have constructed a corpus of annotated drug product inserts taken from the US Food and Drug Administration’s Drugs@FDA online database. In this work, we present the development of the Engineered Nanomedicine Database corpus to support the …

Cloud Workflow Automation, William Crump, Eric Darling, Kyle Hagood, Syed Rizvi

Capstone Design Expo Posters

The goal of our project was to develop an application in the cloud which automates complex business tasks. The application allows users to create configurable events consisting of a trigger followed by an action. Triggers are designed for common tasks such as scanning a directory or email inbox for new files. When a new file is detected, the application triggers the execution of an associated action such as sending an email alerting the user of the changes or processing and moving the files. Users are thus able to automate complex tasks by configuring event sequences, leading to an increase …

Amc Native Webrtc Client, Kellan Childers, Michael Dowling, Sherdil Khawaja

Capstone Design Expo Posters

Traditional call center and telecommunication hardware is being replaced by thin, browser-based, cloud enabled web services. Industry standards for web based communication protocols, such as WebRTC, are being established. AMC needed to address this new technology, while maintaining a hybrid approach of server-based capabilities, taking advantage of the web-based communication channel, while broadcasting events to the Contact Canvas Server. Contact Canvas Agent Palette is the editing platform of the AMC adapter for Salesforce.com, allowing agents to communicate with customers through the AMC adapter/ Softphone. Using Agent Palette, the task was to integrate Video Chat using WebRTC into the AMC toolbar. …

Company Health Dashboard, Zachary Raney, Ahmad Shahir Abdul Satar

Capstone Design Expo Posters

Company Health Dashboard is a web application that serves as a tool to display information in dynamic grid-like modules. This application displays viewer-friendly information on the televisions around the company office using Raspberry Pi devices. In order to benefit different types of users, the application divides the screen into multiple customizable modules, with each module representing different information. Company employees, for example, can view information about company news, upcoming events, or even what’s on tap for that day. Visitors or clients, on the other hand, can see information about the company while waiting for their meeting.

The design of the …

Mapcom Self-Service Portal, Kelsey Bullock, Viet Nguyen, Alvenia Weathers

Capstone Design Expo Posters

Mapcom Systems is a software development firm that primarily serves small, rural telecommunications companies. The company is widely recognized for developing M4 Solutions, a visual operations platform that allows service providers to manage their workforce. Our team was tasked with the design and implementation of a self-service portal to be used by the customers of these telecommunications companies. The application would allow customers to easily manage their accounts, including creating and managing trouble tickets, communicating with their assigned technician, and viewing their scheduled appointments. Additionally, it would be offered across three different platforms: Web, Android, and iOS. In order to …

Richmond Mural Tour, Matthew Mcgee, Paul Mcdonald

Capstone Design Expo Posters

In the past years Richmond has been growing in popularity in the world of street art. This popularity is due in part to the many projects that brought in artists from around the world to create beautiful artwork. There is so much art outside in Richmond as a result of these projects, but no great way to navigate the streets of the city in an efficient manner to see all of it. Richmond Mural Tour is a mobile cross-platform application that allows users to explore all of the amazing outdoor artwork around the city.

This application is built on ionic …

Lab-Scale Reproduction Of Siloxane Foam Synthesis, Albert Deangelis, Benjamin Ledoux, Conrad Roos

Capstone Design Expo Posters

Evonik has a synthesis reaction to create siloxane-based foam for sale that they run in their Hopewell plant. They would like to utilize a bench scale reactor system for experimentation on the process. The problem is that the foam created on the lab scale does not show the same properties as the foam created on the plant scale and to run experiments accurately they would have to use the plant reactor, wasting both reactor time and plant resources. Evonik wanted the Senior Design team to find a way of recreating the conditions of the plant reactor on the lab scale …

Compressible Media For Water Treatment, Christine Forkins, Steven Kammermeier, Antonio Musso

Capstone Design Expo Posters

Tertiary water treatment is used to remove total suspended solids (TSS) from wastewater. Suez uses compressible media for their tertiary water treatment. There have been supplier issues in the past such as unreliability, long lead-times, unknown manufacturing process, and chances of resale. The chance of resale is an important issue because the specifications may change from one supplier to another.

The group was tasked to characterize different types of compressible media for water treatment, design a lab scale filtration unit, and design and manufacture a new media to be tested. In order to gain an operational expenditure advantage, Suez accomplishes …

Hazardous Waste Reduction Continuation, J. Brian Morrell, Alex Alvarez, Adnan Qasem

Capstone Design Expo Posters

A silicone manufacturing process yields two-phase wastewater, of which the aqueous phase flashes at 2°C primarily due to hexamethyldisiloxane (HMDSO). To be classified as non-hazardous and immediately disposable, it must flash above 60°C. Project objectives entailed identifying a method and then designing a prototype for on-site aqueous phase treatment, removing enough HMDSO for non-hazardous disposal. The previous team’s proposal was gravity separation, NaCl extraction, and feeding through an activated carbon packed bed. Extraction proved ineffective, packed bed outlet samples flashed at 52°C, and HMDSO quantification methodology was incorrect. From titration, wastewater was determined to be 3.3 ± 0.2 wt.% aqueous …

Rapid, Diagnostic Test For Cardiac Ischemia, Jose Gonzales, Abdelmagid Nasreldeen, Emerson Physioc, Julio Contreras, Evan Thoresen

Capstone Design Expo Posters

Current methods to detect cardiac ischemia rely on biomarkers such as troponin. Elevated levels of troponin are observed hours after the cardiac event. There is an unmet need for rapid diagnostic tests for cardiac ischemia, which utilizes recently discovered biomarkers. A VCU patented assay for cardiac ischemia employs the use of chemiluminescence to detect metabolic byproducts of xanthine oxidase activity. These byproducts are detectable minutes after the cardiac event. Early diagnosis of and response to cardiac events is beneficial for clinical decision-making; therefore, a point-of-care device within the emergency health setting is sought. The CLSE 203 project team designed and …

Improved Mixing System For Aquatic Mesocosm Facility, Kyle Boyce, Ben Chalfant, Ron Fitch

Capstone Design Expo Posters

The VCU Environmental Science Department had in its possession 24 500 gal tanks they had implemented to study the plankton and bacteria activity of the James River. Water was pumped up from the James River a quarter mile to the tanks and studied over week long periods to analyze the growth and survival of plankton and bacteria as it exists in the river. Over time it was found that the bacteria in the mesocosms would growth at an increased rate as sediments and inorganic matter fell out of suspensions. For this reason, it was necessary to develop an agitator that …

Development Of A Tabletop Soft Gel Encapsulation Machine, Brigitte Ha, Emily Miller, Haya Rizvi

Capstone Design Expo Posters

Currently, to test new formulations of gel capsules at Pfizer, they must use the large-scale machine that requires a minimum of 25 kg of gel melt and produce hundreds of capsules per run. Production at a smaller scale to enable rapid changeover for research and development is desired. The team’s goal was to achieve continuous production of sealed capsules with 80% fill capacity. Capsule sealing was the prime consideration. Preliminary trials using the existing system and heat transfer analysis indicated localized heating was necessary to promote capsule sealing. To provide localized heating, a brass wedge was designed based on the …

Rapid Detection Of Nicotine In E-Liquids, Niraja Bohidar, Ryan Joiner, Benjamin Kirby

Capstone Design Expo Posters

Electronic cigarettes have gained popularity in recent years. Electronic cigarettes operate by vaporizing flavored solutions, called e-liquids, for inhalation by the user. No method is currently available for analysis of e-liquids in the field, making regulation of electronic cigarettes difficult and inefficient. Some regulatory issues related to e-liquids include mislabeling of e-liquids by providers to avoid taxes on nicotine, the sale of nicotine-containing e-liquids to minors, and the mixing of drugs of abuse into e-liquids. Regulatory and law enforcement agencies have a need for an accurate field test capable of analyzing e-liquids for nicotine. Proposed are two devices for the …

Vertical Take-Off And Landing Aircraft, Sophie Baldwin, Michael Pennie, Alex Roberts, Dov Szego

Capstone Design Expo Posters

The primary purpose of this project is to combine the benefits of both multi-copters and fixed-wing crafts, reducing the drawbacks of both. The explosion of small unmanned aerial systems (“UASs”), also called unmanned aerial vehicles (“UAV”) in recent years is the result of their versatility and practicality. It is invaluable for obvious reasons to be able to send a small, comparatively inexpensive, remotely controlled vehicle with a camera or a payload into places where either people cannot or would prefer not to go. Quadcopters have the advantage of being able to take off and land without significant runway space, but …

Smart Exoskeleton Hand With Soft Electronics, Andrew Choi, Han Ha, Gabrielle Jones, Gregory Zobel

Capstone Design Expo Posters

Many people in the modern world suffer from a loss of hand and finger strength due to diseases in the muscle or nervous system such as ALS, Muscular Atrophy, and more. This problem has become more widespread with the surge of technology over the last 5-10 years. Therefore, we have created a smart exoskeleton hand with soft electronics that will allow people with less than average hand strength to perform daily activities.

The exoskeleton device utilizes small, lightweight linear actuators to provide additional strength to the user’s fingers and the hand itself will be 3D-printed with ABS and PLA plastics …

Wearable Device To Detect Cardiac Arrest, Jon Dyke, Majid Alashari, Ashraf Al Gumaei

Capstone Design Expo Posters

Cardiac arrest is one of the leading causes of death globally and is unwitnessed in most cases. This begs the question: how can anyone know that an individual is experiencing cardiac arrest if no one is around to see it? MULT 603 has designed a cardiac arrest monitoring device that a person can wear on their wrist. This device detects the individual’s heartbeat; in the case that the person’s heartbeat drops below their normal individual threshold, their family, doctors, and friends along with emergency medical services will be notified of their location and condition. The hope is to drastically improve …

Low Cost, Adhesion Strength Based Cell Sorter, Emily Burtch, Franck Kamga-Gninzeko, Devin Mair, Sarah Saunders

Capstone Design Expo Posters

In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells. Recently, it was discovered that different cell types adhere to cell culture dishes at different strengths. This observation was utilized in the invention of a cell sorting system that sorts cells based on this adhesion strength difference. The resulting system is marketable at under $2000, compared to $50000 plus for current commercially available systems, and is the first commercially-oriented cell adhesion strength based cell …

Finite Element Analysis Of A Friction Clutch System In An Automatic Transmission, Samuel Cook

Capstone Design Expo Posters

The purpose of this project is to develop a computational solution to the effects of certain variables present inside an automatic transmission, more specifically, the friction clutch system that enables and disables different gear-sets. Afton partnered with the School of Engineering looking for a time-sensitive, computational solution to serve as a valuable comparison to what exists at Afton’s disposal currently. The solution is a finite element analysis (FEA) simulation that transforms a real world device with many nuances and intricacies into a simplified model in a two dimensional test space. The challenge exists in keeping the simplified model accurate to …

3d Printed Ear Canal Model, Ahmad Ali, Rosheena Hairston, Hunter Locks

Capstone Design Expo Posters

A multi-material ear canal model was designed and created from CT scans of an actual patient. This ear canal model serves as a training model for trainees, surgeons and doctors to develop a better understanding of the anatomy and physiology of the ear by physically looking, touching and testing the model. The major task taken was to establish and identify the area of interest provided with the files of medical scans by using 3D Slicer. The files were then converted to a stereolithographic (STL) file where it was able to be edited for smoothing in programs such as Meshmixer or …

Radiotherapy Ergonomic Patient Positioning System, Anthony Briscoe Ii, Joseph Oliva, Yvette Smith, Darius Stuvaints

Capstone Design Expo Posters

External beam radiotherapy is a powerful tool to combat cancer, but requires precise positioning of patients. The standard practice involves patients lying on treatment tables within immobilization equipment. These systems have limited clearance between treatment sources and the patient that can be uncomfortable or claustrophobic for patients. Patients may move when uncomfortable, leading to improper dose delivery, possibly causing painful side effects or further cancers. We present an alternative, open configuration patient positioning solution for more ergonomic setup options with competitive positioning capabilities compared to conventional systems.

Our ergonomic positioning system consists of a seat for patients on a scissor …

Underwater Ant House, Mark Duggan, Zachary Ellis, Zachary Soulier

Capstone Design Expo Posters

The project seeks to design and test and submersible enclosure capable of sustaining oxygen breathing life. A mesh covered in a superhydrophobic coating can both restrain water up to a maximum pressure and retain a direct interface between air and water. Oxygen can transfer over this boundary if there is a sufficient difference in concentrations between the water and air.

Multiple designs have been produced with the intent of testing and demonstrating these theories. 3D printing allowed for quick and customizable production of every component. Enclosures were made for testing the maximum allowable pressure and to fit an oxygen sensor. …

Reducing Noise In Automatic Transmission, Connor Golden-Weathers, Riley Hall, Matthew Bosco, Felix Pyatigorskiy

Capstone Design Expo Posters

The efficiency of an automobile increases as its running torque increases. This is an avenue for improving fuel economy that is actively being pursued. However, transmissions running at higher torques produce an unacceptable amount of noise, vibration, and harshness (NVH). NVH occurs most visibly as a result of the vehicle’s friction clutch behavior. At present, machines capable of testing this behavior exist (MTM machine and LVFA rig) but are very expensive in terms of time, space, and production cost.

The goal of this project is to produce a cost-effective machine in which friction clutch behavior can be analyzed in a …

Media Mixing Apparatus, Nick Colt, Eric Depew, Kurt Thoele, Chris Ward

Capstone Design Expo Posters

The purpose of this project is to reduce the physical exertion and radiological exposure of the maintenance worker by reducing mixing time of water and resin beads when replacing resin beads in a shipboard tank. Presently, a maintenance worker empties ⅓ cubic foot of resin media into a bucket, and fills the bucket with about 1-⅓ gallons of water. Then the water and resin media is mixed with a paddle by hand, until it appears homogeneous, creating a slurry. The slurry is dumped into a funnel after the mixing process and introduced to the system after the discharge valve is …

Unattended Underground Energy Harvesting Sensor, Jeffrey Buck, Tzshay Wade, Jaeton Foxley, Brandon Ruffin

Capstone Design Expo Posters

The team designed an underground energy harvesting sensor that utilizes the ambient energy from its surroundings to provide low power telecommunications to a remote host. The scope of this project is to analyze the feasibility of such system and explore the capabilities of available energy harvesting techniques that utilize the environment, feasibility of operation, and creating a design. Some of the most common methods that have been proven to function on certain environments are thermoelectric and solar energy. Thermoelectricity uses a temperature gradient and solar uses the energy of the sun. To provide a remote vibration signal an accelerometer was …

Explosion Damping Device (Blast Shield), Cullen Bade, Juwan Cephas, Raymond Long

Capstone Design Expo Posters

The proposed device has the main goal to protect a vehicle and personal inside the vehicle in the event of an explosion from underneath of a Humvee most likely caused by an IED explosion. The constraints were that the vehicle could not be lifted too far off the ground to increase the chance the vehicle rollover; the design should not block accessibility to the passengers; be versatile in order to help fit different model vehicles; and most important be able to help in deflecting the blast away from the vehicle. The final design consisted on a V-shaped blast shield similar …