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Utah State University

Theses/Dissertations

2015

A549

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Full-Text Articles in Engineering

The Effect Of Polydimethylsiloxane Substrate Modification On A549 Human Epithelial Lung Cancer Cell Morphology And Biomechanics, Sherissa A. Ward May 2015

The Effect Of Polydimethylsiloxane Substrate Modification On A549 Human Epithelial Lung Cancer Cell Morphology And Biomechanics, Sherissa A. Ward

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The function of cells is dependent on factors including chemical, physical, and mechanical stimuli. A compilation of these factors make up the cellular niche. Though the impact of chemical stimuli has been a known factor for many years, the impact of mechanical and physical stimuli are areas of recent interest now being studied. Previous studies on mechanical and physical stimuli have shown a large impact on various aspects of cellular function.

The effects of cancer are wide spread throughout the entire population. The majority of cancer research and treatment is regarding intracellular chemical pathways. Yet, many forms of cancer are …