Engineering Commons^™

Three-Dimensional Hydrodynamic Focusing For Integrated Optofluidic Detection Enhancement, Eric Scott Hamilton

Utah Space Grant Consortium

Integrated optofluidics are ideal for high sensitivity detection due to the size of device features being near the small scale of sample particles (10 microns). Novel integrated optofluidic designs enable single molecule detection through hydrodynamic focusing, making the approach ideal for low concentration biosensing. Detection was enhanced and device operation characterized. Further enhancement is promised with optimization of existing designs.

Effect Of Superhydrophobic Surface Microstructure On Transient Jet Impingement Cooling, D. Jacob Butterfield, John Morris

Utah Space Grant Consortium

Jet impingement is an effective method of rapid surface cooling, and is highly dependent on surface condition and properties. Here, silicon surfaces are modified by ion-etching different micropatterns (posts or holes) on one side and coated with Teflon to make them superhydrophobic (SH). The other side of the surface has a screen-printed resistance heater. Surfaces are heated to temperatures between 200 to 320 °C, and then impinged on by a pure water jet at room temperature with flow rates ranging from 6 to 18 mL/s. Results show that there is little effect of microstructure, although hole surfaces and shorter microstructures …

Masking And Detecting Radiation-Induced Errors In Sram-Based Fpgas Through Partial Circuit Replication, Andrew M. Keller

Utah Space Grant Consortium

Radiation found in terrestrial and space environments can induce errors into SRAM-based FPGAs. Replication of circuitry can be used mask and detect these errors to improve reliability or availability. This work advances the understanding and implementation of partial circuit replication in SRAM-based FPGAs. Partial circuit replication is the replication of a subset of the components in a circuit. A reliability model is presented that evaluates the reliability benefit of partial circuit replication. The model suggests that the reliability benefit is inversely related to the portion of the circuit replicated. A partial triple module redundancy case study is also presented that …

Assessing The Impact Of Drop Velocity And Spacing In Binder Jetting To Improve Printing In Novel Powders And New Environments, Trenton Colton

Utah Space Grant Consortium

Binder Jetting (BJ) is a low-cost Additive Manufacturing (AM) process that uses inkjet technology to selectively bind particles in a powder bed. The interaction of the binder droplets with the powder is essential to the process. This is a complex interaction in which picoliter-sized droplets impact powder beds at velocities of approximately 10 m/s. The binder partially fills the voids between the powders. The fraction of void space filled with binder is the saturation and is a key parameter in BJ. The effects of printing parameters such as droplet velocity, size, and spacing on saturation levels are unknown. This study …

Investigating Novel Biomarkers Associated With Aki Diagnosis And Risk, Lars Lofgren, Natalie Silverton

Utah Space Grant Consortium

Acute kidney injury (AKI) is a common complication associated with cardiac surgery. Those patients who develop AKI have increased hospital costs, hospital LOS and odds of death. The current diagnostic criteria rely on serum creatinine measurements and urine output data. Serum creatinine is not renal specific. It is known that there are other factors that influence serum creatine concentrations other than renal injury. Serum creatinine levels are measured as concentrations which means large changes in fluid balance may alter the serum creatinine measurement. Urine output is not a reliable measurement of renal injury either. During surgery it is common to …

An Examination Into The Defining Characteristics Of Flexible Solar Aircraft Configurations Through Optimization, Taylor Mcdonnell

Utah Space Grant Consortium

This paper examines the defining characteristics of various solar aircraft configurations through gradient-based multidisciplinary design optimization. We first present a general gradient-based solar aircraft optimization framework which accounts for nonlinear aeroelastic effects resulting from structural flexibility. We then apply this framework to several discrete SR-HALE aircraft geometric, structural, and propulsion system configuration choices to determine the defining characteristics of each configuration choice.

Development Of An Inertial Measurement-Based Assessment Of Disease Severity In Chronic Fatigue Syndrome, Turner Palombo, Suzanne Vernon, Shad Roundy

Utah Space Grant Consortium

While myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is relatively new and poorly understood, a recent upsurge in research has identified the disease’s core symptoms, including post-exertional malaise and orthostatic intolerance. The FDA has yet to approve any treatments for ME/CFS, partially due to a lack of validated efficacy endpoints.

The central focus of this research is to develop ME/CFS efficacy endpoints using a non-invasive, inertial measurement-based approach. Accessible endpoints will provide a way to properly evaluate potential treatments for ME/CFS. Using a Kalman filter, inertial measurement unit (IMU) data can be converted to optimized leg angle estimates. These angle estimates can …

Comparison Of Wake Expansion Methods For Use In Wake Expansion Continuation Optimization, Jared J. Thomas

Utah Space Grant Consortium

This paper presents a comparison of three methods for expanding the wake for use with wake expansion continuation (WEC) optimization. A process related to continuation optimization methods for reducing multi-modality in the wind farm layout optimization problem. A reduction in multi-modality is achieved by starting with an increased wake spread, while maintaining normal velocity deficits at the center of the wakes, and then reducing the wake spread for each of a series of optimization runs until the standard wake spread is used. Three wake expansion methods were tested: (1) increasing the wake expansion angle, (2) multiplying the wake diameter, and …

Ultra-Low Power Adcs For Space Sensors And Instruments, Shea Smith, Wood Chiang

Utah Space Grant Consortium

A 28nm 0.1V 10-bit 2kS/s Successive Approximation Register ADC design is proposed. This design opens the doors to both low supply and low power space sensors and instruments. Due to the stringent voltage supply unique challenges arise that are met with innovation in the sample switch and comparator design. These components of the ADC architecture are optimized to perform successfully at a 0.1V supply with a sample rate suitable for most sensor applications.

Spectral Absorption Coefficient Of Additive Manufacturing Polymers, Nicholas J. Wallace, Matthew R. Jones, Nathan B. Crane

Utah Space Grant Consortium

As NASA turns to additive manufacturing processes, there is a need to ensure that the parts they produce are reliable. This is especially true when creating parts in space, where resources are limited and failure could result in catastrophe. Active thermography has shown potential as a non-destructive quality assurance technique for additive manufacturing processes. Heat transfer models used in active thermography techniques require accurate material property measurements in order to extract useful information about the system, including defect location. The spectral absorption coefficient, which determines the depth at which radiative power is absorbed into a surface, is a material property …

Advancing Space Flight Medical Care Through On-Demand Protein Therapeutic Production Capabilities, Emily Long Zhao

Utah Space Grant Consortium

Cell-free protein synthesis (CFPS) is an in vitro protein synthesis system that provides a uniquely adaptable platform for protein production. In recent years, lyophilization of CFPS have expanded the capabilities of this system by improving reagent stability outside of cold-chain storage. This project sought to utilize lyophilized CFPS reagents to develop a convenient, shelf-stable, on-demand therapeutic protein production platform. The therapeutic protein production potential of this novel platform was demonstrated by the successful expression of an FDA approved therapeutic protein. With the advancement of shelf-stable, on-demand protein therapeutic production platforms comes the potential to provide point-of-care medical treatment for space-flight …

Improving Technologies In Anesthesia, Patrick Kolbay, Joseph Orr

Utah Space Grant Consortium

General anesthesia is well known to offer physicians access to a broad variety of invasive procedures otherwise deemed too risky. Anesthesia machines provides the means for anesthetizing patients safely in the hospital operating room. However, these devices are increasingly unable to meet the demands and needs outside of the hospital. Developing countries struggle to purchase and maintain these costly devices, leading to a 40-fold increase in anesthesia-related deaths compared to developed countries. Small-office practices in the United States experience significantly poorer anesthesia outcomes and increased legal claims versus their larger hospital counterparts, resulting in 60% more anesthesia-related deaths. Environmental impacts …

Model Reference Predictive Adaptive Control For Large Scale Soft Robots, Phillip Hyatt, Curtis Johnson

Utah Space Grant Consortium

Past work has shown Model Predictive Control (MPC) to be an effective strategy for controlling continuum joint soft robots using rudimentary models, however the in-accuracies of these models often mean that an integration scheme must be combined with MPC. Presented in this work is a novel dynamic model formulation for continuum joint soft robots which is more accurate than the authors’ previous models yet remains fast enough for MPC. This model is based on the Piecewise Constant Curvature (PCC) assumption and a relatively new configuration representation and allows for computationally efficient simulation. Due to the difficulty in determining model parameters …

A Reinforcement Learning Based Control Approach For Propofol-Induced Burst Suppression, Jason C. Huang, Scott C. Tadler, Brian J. Mickey, Keith Jones

Utah Space Grant Consortium

High-dose propofol is being investigated for its potential antidepressant effect. Propofol is titrated to induce burst suppression, a specific EEG pattern. However, propofol is difficult to dose due to uncertainty in each patient’s pharmacokinetics (PK) and pharmacodynamics (PD), and the lack of a commercially available monitor of propofol concentration. Clinicians currently infer the proper drug dose after observing the EEG response to the given dose. In this report we share our development of an automated controller to optimally administer propofol-induced burst suppression. We designed a deep deterministic policy gradient (DDPG) algorithm, which includes two deep neural networks and relates a …

Advanced Video Laryngoscope And Automatic Data Collection System, Gabrielle Hoyer, Sean Runnels, Samer Merchant

Utah Space Grant Consortium

The Advanced Video Laryngoscope is designed to address the high stress situation of an inexperienced healthcare provider performing an intubation on a patient. The technology is superior to current video laryngoscopes in that it utilizes machine learning techniques to guide the healthcare provider in real-time, providing augmented reality cues to anatomical features, feedback to prevent critical levels of deoxygenation of the patient, and an automated system to assess the difficulty of airway and call on the assistance of other physicians if first-pass intubation is not successful. By providing real-time assistance to the operator, this device will increase the success rate …

Influence Of Electrode Height On Carbon Nanotube Electrochemical Biosensors, Benjamin J. Brownlee

Utah Space Grant Consortium

High sensitivity of electrochemical sensors enables the detection of low concentrations of target analyte. Being able to quickly and accurately detect low concentrations of proteins at point-of-care allows for results to be analyzed more easily and effectively. Having high surface area allows for more analyte to be detected, possibly leading to increased sensitivity. Vertically-aligned carbon nanotubes (VACNTs) were patterned into interdigitated electrodes (IDEs) and then functionalized with the representative protein streptavidin to demonstrate sensing of biotin. Three electrode heights were investigated to determine the influence of electrode height on sensor sensitivity. Cyclic voltammetry and electrochemical impedance spectroscopy were used to …

Evolutionary Nonlinear Model Predictive Control On A Fixed-Wing And Multirotor, Jaron Ellingson, Matthew Haskell

Utah Space Grant Consortium

Real-time model predictive control (MPC) is limited to short time horizons and linear systems because the optimization complexity is too large with long time horizons and nonlinear systems. For this reason, MPC is typically accomplished using linearized models and convex optimization solvers. We seek to explore evolutionary algorithms allowing for nonlinear models and constraints, non-convex costs, and extended time horizons.

Our contributions include extending nonlinear evolutionary MPC to flight vehicles, fixed-wing and multirotor UAVs, as well as enhancing the evolutionary algorithm. We also intend to parameterize the design space of the optimization to reduce solve times. These contributions validate the …

Applying Real-World Learning Through Amusement Parks To Help Teach The Upcoming Changes To Utah Core Standard, Phil Lundgreen, Amanda Otterstrom

Utah Space Grant Consortium

To assist educators in satisfying the Science with Engineering Education (SEEd) Standards the Utah State University (USU) Physics Department has developed a curriculum centered around USU Physics Day at Lagoon.

With an upcoming change to Utah's core standards and a shift to more hands-on learning styles, the use of real-world learning offered by amusement park applications is analyzed in its ability to satisfy the Utah State Bureau of Education’s (USBE) SEEd standards. Amusement park learning allows educators a vehicle to capture students’ attention in the classroom by discussing science principles in a fun and exciting manner with a promise of …

Aerodynamic Interactions Of Synchronized Propellers, Nathan Welker, Samuel Johnson

Utah Space Grant Consortium

Emerging advances in electric-propulsion technology are enabling aircraft to use distributed electric propulsion (DEP) to increase efficiency and maneuverability. Distributed electric propulsion can also provide unique take-off and landing abilities which are not commonly found on traditional aircraft. The implementation of DEP effectively decreases the spacing between propellers, introducing complex aerodynamic interactions that are not well understood. This study aims to obtain experimental measurements of the flow fields of synchronized propellers at close-proximity in a side-by-side configuration using particle image velocimetry (PIV) in a wind tunnel. The results of this work will be focused on identifying the impact closely-spaced propellers …

Monte-Carlo Methods And The Step-Back Kalman Filter For Orbital State Estimation, Louis Tonc

Utah Space Grant Consortium

This research assesses the performance of filtering schemes for tracking uncooperative satellites through space-based optical measurements, and identifies a simple and numerically stable methodology that ameliorates the poor performance of standard filtering schemes at a substantially reduced cost in comparison to nonlinear particle filter-based remedies. Traditional filtering schemes, such as the extended Kalman filter (EKF) and unscented Kalman filter (UKF), both diverge when tracking a resident space object (RSO) in geosynchronous orbit (GEO) when there is a long time duration between measurements. This divergence is identified as a consequence of nonlinearity in the dynamics and nonlinearity in the optical measurements, …

One-Dimensional Turbulence Modeling Of Soot Formation And Transport In Non-Premixed Turbulent Flames, Victoria B. Stephens

Utah Space Grant Consortium

Soot modeling in turbulent flames involves tightly coupled problems of combustion chemistry, particle transport, compressible fluid dynamics, and turbulence behavior in addition to soot chemistry and transport. Significant uncertainties accompany soot modeling and transport in such systems, hindering progress toward accurate combustion models and predictive simulation tools. The one-dimensional turbulence (ODT) model, using a stochastic approach to turbulence modeling, captures the full range of length and time scales in a simulation and provides detailed statistical data of the flow con-figuration, chemistry, and particle transport. Previously, ODT has demonstrated accuracy and computational efficiency compared to direct numerical simulation (DNS) of turbulent, …

Validating A Finite Element Model With Ansys Workbench For Isotruss® Structures Subject To Uniaxial Compression, Hanna B. Opdahl

Utah Space Grant Consortium

The purpose of this study is to develop, verify, and validate a finite element (FE) model of IsoTruss® structures subject to uniaxial compression. The FE model is implemented in ANSYS WorkBench and verified using axial stiffness and critical buckling loads that are derived from traditional mechanics. The buckling failure modes include global buckling and local bay buckling. The predictions from the FE model and mechanics calculations are validated by experimental data generated in preceding studies. Results indicate that the effective material modulus is highly affected by variations in manufacturing. Adjustment factors are applied to the nominal material properties to accurately …

Leveraging Commercial Nuclear Reactors To Power Space Exploration, Ben Johnson

Utah Space Grant Consortium

This study is aimed at exploring the adaptation of commercial nuclear reactors as an alternative to NASA’s current high-power fission reactor systems, particularly with respect to applications on the surface of Mars. The study concludes that while the Kilopower architecture is brilliantly poised to provide affordable, near-term power in the 1-10 kilowatts electric (kWe) range, the financial barrier to higher power scaling of such systems is significant. This financial barrier adds risk to the development of greater than 10kWe systems and is likely to result in the failure to successfully scale the technology to higher powers for space exploration applications. …

Ensuring Extramobile And Intramobile Motion On Cylindrical Developable Mechanisms, Jared Butler

Utah Space Grant Consortium

Developable mechanisms offer the ability to deploy to perform tasks then return to a hidden position along or interior to a predetermined developable surface. It is often advantageous for these mechanisms to not penetrate the surface along which they conform. This paper presents the limits of extramobile and intramobile motion (motion exterior to and interior to a developable surface). Three conditions are identified that determine a limit of extramobile and intramobile behavior. It is shown that the more difficult of these conditions to predict is never reached prior to the more simple cases. This is demonstrated for all possible Grashof …