Engineering Commons^™

Investigation Of The Biosynthetic Process Of Indigoidine, Yi Chen

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Indigoidine is a natural blue dye with antioxidant and antimicrobial activities. It has also been used as an indicator for gene expression based on its distinctive blue color. Similar to the industry blue dye indigo, indigoidine has a promising potential to be applied in industry as a blue dye. However, the indigoidine production level in the original microorganisms was very low. Heterologous expression of the responsible synthetase gene in Escherichia coli can facilitate the fast and large-scale production of indigoidine. Also, a good understating of the working mechanism of the synthetase is favorable for the industrial application.

In our previous …

Comparison Of Induced And Parasitic Drag On Wings With Minimum Induced Drag, Sarah A. Abdel-Motaleb

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Minimizing the induced drag for steady level flight is a variational problem that requires solving for the optimum lift distribution given a set of design constraints. From lifting-line theory, minimizing the induced drag is, in part, achieved by varying the Fourier coefficients used to describe the section lift. The elliptic lift distribution minimizes the induced drag for a wing with fixed weight and wingspan by setting all but the first coefficient to zero. If wingspan is allowed to vary, a negative third Fourier coefficient is utilized to reach an optimum lift distribution that further reduces the induced drag for stress-limited …

A Swimming Open-Water Navigation Assistive Headset And Receiver, Zakk B. Rhodes

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Open water swimming is a common activity dating back to ancient times. One challenge with open water swimming is navigation because while maintaining proper swimming technique suggests the head be in the water, it is difficult to see where one is going. Thus swimmers must bring their head out of the water periodically to sight landmarks. This work describes a solution to this problem by a design for a GPS device to assist swimmers with navigation. The swimmer can plan their own route, send it to the device, and then be guided by the device. They then will not have …

Cell Imaging And Data Analysis For Biomaterial-Mammalian Co-Cultures, Jefferson Pontsler

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Microscopic bioimaging is a useful approach to study cell-biomaterial interactions which are vital to the biomedical application of biomaterials. Through microscopic imaging, numerous cellular responses, such as proliferation, uptake, and death, can be recorded, characterized and analyzed.

In this thesis, I first provided basic introductions to the imaging techniques and analysis tools, especially those that are highly relevant to the studies of biomaterials and cell interactions. I also detailed the adaptation of these techniques and tools in the application of two specific research projects in biomaterials, with special focuses on the imaging and analysis.

The first project assessed the subtle …

Reconstruction Of Attenuated Hybrid Rocket Motor Chamber Pressure Signals Using Maximum Likelihood Estimation And Optimal Deconvolution, Evan M. Zelesnik

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Chamber pressure, as it develops during rocket combustion, strongly correlates with many of the internal motor ballistics, including combustion stability, fuel regression rate, and mass flow. Chamber pressure is also an essential measurement for calculating achieved thrust coefficient and characteristic velocity. Due to the combustion environment hostility, sensing chamber pressure with high-fidelity presents a difficult measurement problem, especially for solid and hybrid rocket systems where combustion by-products contain high amounts of carbon and other sooty materials. These contaminants tend to deposit within the pneumatic tubing used to transmit pressure oscillations from the thrust chamber to the sensing transducer. Partially clogged …