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University of South Carolina

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Full-Text Articles in Engineering

Leveraging Inflammatory Responses Toward Advancing Alzheimer’S Disease Treatments And Biomaterial Implantation, Mihyun Lim Waugh Oct 2023

Leveraging Inflammatory Responses Toward Advancing Alzheimer’S Disease Treatments And Biomaterial Implantation, Mihyun Lim Waugh

Theses and Dissertations

Inflammation is a body’s physiological response to pathogens, foreign materials, or tissue injury. When immune system is triggered, activated leukocytes produce cytokines and chemokines that promote migration of neutrophils and macrophages to the inflammatory regions. At early stages of injury, acute inflammation occurs immediately to fight off the pathogens and restore tissues to homeostasis. However, if the inflammation-inducing stimulus is not removed and thus cells and tissues do not return to its homeostatic state, the prolonged inflammatory responses become a chronic condition. Recent studies have indicated that the receptor for advanced glycation end-products (RAGE), a key receptor of innate immune …


Floodplain And In-Channel Sedimentation In The Bedrock Congaree River, Sc, Mahsa Ahmadpoor Oct 2023

Floodplain And In-Channel Sedimentation In The Bedrock Congaree River, Sc, Mahsa Ahmadpoor

Theses and Dissertations

The Congaree River planform is characterized by an abrupt increase in channel sinuosity in the downstream direction. Such a change is not typical of alluvial meandering rivers but has been observed in mixed bedrock-alluvial rivers. This motivated the first study of this dissertation, specifically designed to determine if the Congaree River is indeed a mixed bedrock-alluvial river in its low sinuosity (upstream) reach. To test this hypothesis, sonar-based measurements of channel bed and sublayer elevation were performed from Columbia to the Congaree River-Wateree River confluence. The sublayer is here defined as the first surface visible in the sonar measurements underneath …