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Development Of Cellulose Acetate-Based Scaffold For Bone Tissue Engineering Applications, Ruhit Sinha
Development Of Cellulose Acetate-Based Scaffold For Bone Tissue Engineering Applications, Ruhit Sinha
Electronic Theses and Dissertations
Cellulose Acetate (CA) based biomaterials are being used as substrates for bone ingrowth applications due to their nontoxic and nonirritant nature coupled with optimum morphology and stiffness. Electrospinning with additives and/or post-treatment has emerged as a viable protocol to further improve mechanical properties of CA and expand its utility. Herein, we highlight the role of potassium chloride (KCl) in association with airdrying to enhance the elastic modulus and tensile strengths of CA fibers. Salt aggregation in between fibers is observed through Scanning Electron Microscopy (SEM), however, Fourier-transform infrared (FTIR) analysis signifies the interactions between K+ ions and acetyl groups. The …