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Modeling Of Transport In Anatomic Respiratory Airways: Applications In Targeted Drug Delivery And Airborne Pathogenic Transmissions, Mohammad Mehedi Hasan Akash
Modeling Of Transport In Anatomic Respiratory Airways: Applications In Targeted Drug Delivery And Airborne Pathogenic Transmissions, Mohammad Mehedi Hasan Akash
Electronic Theses and Dissertations
This thesis aims to explore the potential of improving the efficacy of drugs for treatment of viral infections by targeting the nasopharynx, which is commonly the first site of infection for many viral pathogens. Currently, intranasal sprays are used, but the standard protocol (“Current Use” or CU) results in suboptimal drug deposition at the nasopharynx. To address this issue, an “Improved Use” or, IU protocol has been proposed, which involves pointing the spray bottle at a shallower angle and aiming slightly towards the cheeks. The IU delivery is also robust to perturbations in spray direction, which highlights the practical utility …
On The Simulation Of Supersonic Flame Holder Cavities With Openfoam, Zachary Chapman
On The Simulation Of Supersonic Flame Holder Cavities With Openfoam, Zachary Chapman
Electronic Theses and Dissertations
One of the next major advancements in the aerospace industry will be hypersonic flight. However, to achieve hypersonic flight, propulsion systems capable of reaching hypersonic speeds need to be developed. One of the more promising hypersonic propulsion systems is the scramjet engine, however, several problems still need to be explored before reliable scramjet engines can be produced, the biggest being keeping the engine ignited. This has led to the use of flame holder cavities to create a region of subsonic flow within the engine to allow combustion to occur. High experimental costs make the use of computational fluid dynamic (CFD) …