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Mimicking The Binding And Unbinding Of Fe3+ With Transferrin Using A Single Biomimetic Nanochannel, Chao Zhao, Xiaosi Li, Lingyan Li, Xiong Gong, Yung Chang, Jie Zheng
Mimicking The Binding And Unbinding Of Fe3+ With Transferrin Using A Single Biomimetic Nanochannel, Chao Zhao, Xiaosi Li, Lingyan Li, Xiong Gong, Yung Chang, Jie Zheng
Xiong Gong
A new type of apo-Tf functionalized nanochannel is developed to achieve the specific and selective binding and unbinding of Fe3+ in a multiple and reversible manner via a protein-conformation-gating mechanism. This ion-responsive biomimetic nanochannel provides a simple, robust, and promising model for studying other biological processes.