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Full-Text Articles in Engineering
Development Of Visualization Tools For 4d Ct Datasets, Burak Erem, David Kaeli, Dana Brooks, George Chen
Development Of Visualization Tools For 4d Ct Datasets, Burak Erem, David Kaeli, Dana Brooks, George Chen
David Kaeli
The objective of this poster is to develop a set of tools to effectively visualize, measure, and annotate 4D (3D + time) Computed Tomography (CT) images of radiation oncology patients for both research and clinical applications. Currently, radiotherapy treatment planning utilizes a 2D perspective of 4D data, thereby reducing the amount of information visually available. This information, such as the shape, movement and location of a tumor is critical in treatment planning. These tools are designed to both improve a user's perspective and analysis of tumor shape, motion, and location during respiration. Furthermore, measurement and annotation tools are designed to …
Controlling Dimensionality In A Systems Approach To Dynamic Multimodal Functional Brain Imaging, Srinivas Laxminarayan, Manu Ben Jonny, Solomon Diamond, Dana Brooks, Gilead Tadmore, Eric Miller, David Boas
Controlling Dimensionality In A Systems Approach To Dynamic Multimodal Functional Brain Imaging, Srinivas Laxminarayan, Manu Ben Jonny, Solomon Diamond, Dana Brooks, Gilead Tadmore, Eric Miller, David Boas
Dana Brooks
The complementary spatial, temporal and specificity advantages of MRI, EEG, MEG, PET and DOT for functional brain imaging motivate interest in multimodal functional brain imaging. State-variable dynamical systems modeling of neural activity and its relation to local hemodynamics further coupled with autonomic physiology offers enhanced spatiotemporal resolution and insight into physiological signals and mechanisms. However, such a model also implies an explosion of state dimension. We discuss strategies for controlling this high dimensionality based on subspace approaches applied to the observed data and the model structure, and also describe some implications for understanding human brain function.
Development Of Visualization Tools For 4d Ct Datasets, Burak Erem, David Kaeli, Dana Brooks, George Chen
Development Of Visualization Tools For 4d Ct Datasets, Burak Erem, David Kaeli, Dana Brooks, George Chen
Dana Brooks
The objective of this poster is to develop a set of tools to effectively visualize, measure, and annotate 4D (3D + time) Computed Tomography (CT) images of radiation oncology patients for both research and clinical applications. Currently, radiotherapy treatment planning utilizes a 2D perspective of 4D data, thereby reducing the amount of information visually available. This information, such as the shape, movement and location of a tumor is critical in treatment planning. These tools are designed to both improve a user's perspective and analysis of tumor shape, motion, and location during respiration. Furthermore, measurement and annotation tools are designed to …
Hemodynamically Constrained Dynamic Diffuse Optical Tomography Under Mammographic Compression, Eleonora Vidolova, Dana H. Brooks, Eric L. Miller, Stefan Carp, David A. Boas
Hemodynamically Constrained Dynamic Diffuse Optical Tomography Under Mammographic Compression, Eleonora Vidolova, Dana H. Brooks, Eric L. Miller, Stefan Carp, David A. Boas
Dana Brooks
This poster considers these points: DOT taken along x-ray mammogram provide valuable functional information, X-ray mammography only gives structural information hard to distinguish between benign and malignant masses, Oxygen consumption (OC) and blood flow (F) contrasts observed between malignant and normal tissue[3, 4], Blood flow, oxygen saturation(SO2), water and lipid distributions could specify the degree of malignancy of a tumor, Physiological changes in the breast due to mammographic compression are significant and should be taken into account[2].
Reconstructing Oxygen Consumption And Blood Flow In Diffuse Optical Tomographic Breast Imaging Under Mammographic Compression, D. Ntuba, S. Carp, G. Boverman, E. Miller, D. Boas, D. Brooks
Reconstructing Oxygen Consumption And Blood Flow In Diffuse Optical Tomographic Breast Imaging Under Mammographic Compression, D. Ntuba, S. Carp, G. Boverman, E. Miller, D. Boas, D. Brooks
Dana Brooks
Introduction: Dual-modality imaging with X-ray mammography, Takes advantage of the strengths of each technique to improve clinical diagnostic capabilities, X-ray has high spatial resolution and provides superior structural information, But, sensitivity of mammography is about 86% [1], X-ray does not relate degree of malignancy and is ionizing, Whereas blood volume, oxygen saturation, water and lipid distributions could specify degree of malignancy of tumor, Enhances ability to use x-ray measurements as a prior for DOT. Acknowledgements: This work was supported by CenSSIS, under the Engineering Research Centers Program of the National Science Foundation (Award # EEC-9986821). D. Boas and S. Carp …
Multi-Spectral Reflectance Confocal Microscopy On Skin, Tianchen Shi, Charles Dimarzio
Multi-Spectral Reflectance Confocal Microscopy On Skin, Tianchen Shi, Charles Dimarzio
Charles A. DiMarzio
Reflectance confocal microscopy is a powerful in-vivo modality for imaging superficial layers of biological tissue, especially for human skin. Three dimensional imaging capability enables confocal microscopy to resolve structures of upper skin layer cells. However, sub-celluar structure and corresponding functional organelles play more important parts in skin diseases diagnosis and monitoring. We present a new multi-spectral reflectance confocal microscopy to achieve sub-celluar functional imaging in skin by utilizing our unique Keck multi-modality microscope. Spectral information and a modified Mie scattering model are incorporated to identify distribution of melanin and mitochondria in cells. Ex-vivo and phantom experimental results are presented. Further …