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Computer-Aided Assessment Of Diagnostic Images For Epidemiological Research, Alison G. Abraham, Donald D. Duncan, Stephen J. Gange, Sheila West
Computer-Aided Assessment Of Diagnostic Images For Epidemiological Research, Alison G. Abraham, Donald D. Duncan, Stephen J. Gange, Sheila West
Electrical and Computer Engineering Faculty Publications and Presentations
Background: Diagnostic images are often assessed for clinical outcomes using subjective methods, which are limited by the skill of the reviewer. Computer-aided diagnosis (CAD) algorithms that assist reviewers in their decisions concerning outcomes have been developed to increase sensitivity and specificity in the clinical setting. However, these systems have not been well utilized in research settings to improve the measurement of clinical endpoints. Reductions in bias through their use could have important implications for etiologic research. Methods: Using the example of cortical cataract detection, we developed an algorithm for assisting a reviewer in evaluating digital images for the presence and …