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Quadrupoles For Remote Electrostimulation Incorporating Bipolar Cancellation, Shu Xiao, Ryo Yamada, Carol Zhou

Bioelectrics Publications

Introduction: A method that utilizes nanosecond bipolar cancellation (BPC) near a quadrupole electrodes to suppress a biological response but cancels the distal BPC at the quadrupole center, i.e., cancellation of cancellation (CANCAN), may allow for a remote focused stimulation at the quadrupole center.

Objectives: The primary object of this study was to outline the requirement of the CANCAN implementation and select an effective quadrupole configuration.

Results: We have studied three quadrupole electrode configurations, a rod quadrupole, a plate quadrupole (Plate-Q), and a resistor quadrupole. The pulse shapes of electric fields include monophasic pulses, cancellation pulses, and additive pulses. The Plate-Q …