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New Jersey Institute of Technology

Theses

2005

Effects of

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Combined Effects Of Prozac And Hypothalmic Mediated Response On Masseter Muscle Activity In The Cat, Chika P. Nwaorgu Aug 2005

Combined Effects Of Prozac And Hypothalmic Mediated Response On Masseter Muscle Activity In The Cat, Chika P. Nwaorgu

Theses

The present study tested the hypothesis that infusion of Prozac would serve to suppress defensive rage elicited from the medial hypothalamus of the cat. Cats are known to exhibit certain kind of behavior, known as the "defensive rage response" such as unsheathing of the claws, retraction of the ear and vocalization (hissing).

Three adult cats (2 males and 1 female) weighing (2.8 - 3.4 kg) were utilized during the experiments. Cannula-electrodes were implanted into the medial hypothalamus for elicitation of defensive rage behavior. EMG activity was recorded with a bipolar electrode attached to the masseter muscle to establish baseline before …