Engineering Commons^™

Ph Parametric Pumping : An Examination Of Different Feed Locations For A Two And Three Column Process With The Same Flow Patterns And Ph Distribution, Roberta Rosty

Theses

PH parametric pumping is used to separate protein mixtures of hemoglobin and Albumin.

In this thesis, modifications to a two-column process, where the fluid stage flow pattern and the pH distributions were constant, were explored. These modifications consisted of: changes in the feed stream inlet and outlet locations, changes in the amount of feed itself, and an addition of another column and reservoir to the original two-column process. The results were obtained through computer simulation.

Results indicate that the batch or no-feed two and three column processes yield better separations of the two proteins than the same processes with feed …

Design Of A Gear Driven Anti-Twister Mechanism For A Seal-Less Blood Processor, Ajit Nachiket Dastane

Theses

This thesis presents the design of a gear driven anti- twister mechanism for a blood cell separator. The anti- twister mechanism allows for continuous feed and discharge lines that are rigidly attached to the rotating centrifuge head, thus eliminating the need of rotating seals. It is anticipated that the device using a gear driven anti-twister mechanism will have smoother power transmission and closer rpm tolerances.

In addition, a procedure for the dynamic analysis of the existing device, which uses a belt-driven anti-twister mechanism, is developed. The experimental values obtained from the device are compared with the theoretical values obtained by …