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Scatterer Size Estimation In Pulse-Echo Ultrasound Using Focused Sources: Calibration Measurements And Phantom Experiments, Timothy A. Bigelow, William D. O'Brien
Scatterer Size Estimation In Pulse-Echo Ultrasound Using Focused Sources: Calibration Measurements And Phantom Experiments, Timothy A. Bigelow, William D. O'Brien
Timothy A. Bigelow
In a companion paper [T. A. Bigelow and W. D. O'Brien Jr., J. Acoust. Soc. Am. 116, 578 (2004)], theory, supported by simulations, showed that accurate scatterer size estimates could be obtained using highly focused sources provided that the derived generalized attenuation-compensation function was used and the velocity potential field near the focus could be approximated as a three-dimensional Gaussian. Herein, the theory is further evaluated via experimental studies. A calibration technique is developed to find the necessary equivalent Gaussian dimensions for a focused source using reflections obtained from a rigid plane scanned through the focus. Then, the theoretical analysis …
Scatterer Size Estimation In Pulse-Echo Ultrasound Using Focused Sources: Theoretical Approximations And Simulation Analysis, Timothy A. Bigelow, William D. O'Brien
Scatterer Size Estimation In Pulse-Echo Ultrasound Using Focused Sources: Theoretical Approximations And Simulation Analysis, Timothy A. Bigelow, William D. O'Brien
Timothy A. Bigelow
The speckle in ultrasound images has long been thought to contain information related to the tissue microstructure. Many different investigators have analyzed the frequency characteristics of the backscattered signals to estimate the scatterer acoustic concentration and size. Previous work has been mostly restricted to unfocused or weakly focused ultrasound sources, thus limiting its implementation with diagnostically relevant fields. Herein, we derive equations capable of estimating the size of a-scatterer for any reasonably focused source provided that the velocity potential field in the focal region can be approximated as a three-dimensional Gaussian beam, scatterers are a sufficient distance from the source, …