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Full-Text Articles in Engineering

Signal Processing Strategies That Improve Performance And Understanding Of The Quantitative Ultrasound Spectral Fit Algorithm, Timothy A. Bigelow, William D. O'Brien Sep 2005

Signal Processing Strategies That Improve Performance And Understanding Of The Quantitative Ultrasound Spectral Fit Algorithm, Timothy A. Bigelow, William D. O'Brien

Timothy A. Bigelow

Quantifying the size of the tissue microstructure using the backscattered power spectrum has had limited success due to frequency-dependent attenuation along the propagation path, thus masking the frequency dependence of the scatterer size. Previously, the SPECTRAL FIT algorithm was developed to solve for total attenuation and scatterer size simultaneously [Bigelow et al., J. Acoust. Soc. Am. 117, 1431-1439 (2005)]. Herein, the outcomes from signal processing strategies on the SPECTRAL FIT algorithm are investigated. The signal processing methods can be grouped into two categories, viz., methods that improve the performance of the algorithm and methods that provide insight. The methods that …


A Model For Estimating Ultrasound Attenuation Along The Propagation Path To The Fetus From Backscattered Waveforms, Timothy A. Bigelow, William D. O'Brien Aug 2005

A Model For Estimating Ultrasound Attenuation Along The Propagation Path To The Fetus From Backscattered Waveforms, Timothy A. Bigelow, William D. O'Brien

Timothy A. Bigelow

Accurate estimates of the ultrasound pressure and/or intensity incident on the developing fetus on a patient-specific basis could improve the diagnostic potential of medical ultrasound by allowing the clinician to increase the transmit power while still avoiding the potential for harmful bioeffects. Neglecting nonlinear effects, the pressure/intensity can be estimated if an accurate estimate of the attenuation along the propagation path (i.e., total attenuation) can be obtained. Herein, a method for determining the total attenuation from the backscattered power spectrum from the developing fetus is proposed. The boundaries between amnion and either the fetus' skull or soft tissue are each …


Estimation Of Total Attenuation And Scatterer Size From Backscattered Ultrasound Waveforms, Timothy A. Bigelow, Michael L. Oelze, William D. O'Brien Mar 2005

Estimation Of Total Attenuation And Scatterer Size From Backscattered Ultrasound Waveforms, Timothy A. Bigelow, Michael L. Oelze, William D. O'Brien

Timothy A. Bigelow

Quantitative ultrasound techniques using backscattered echoes have had limited success in vivo due to the frequency-dependent attenuation along the entire propagation path masking the frequency dependence of the backscatter. Herein, total attenuation and scatterer size are estimated simultaneously by an analysis of the in vivo backscattered power spectrum using two approaches. The simulations used to evaluate the two approaches used frequencies between 4 and 11 MHz with an effective scatterer radius of 25 μm. The first approach was based on approximations of the in vivo backscattered power spectrum (i.e., assumed Gaussian function), wherein attenuation and size were estimated by assuming …