Engineering Commons^™

Cascade Control Of A Hydraulic Prosthetic Knee, Xin Hui

ETD Archive

A leg prosthesis test robot with hydraulic knee actuator is modeled and tested with closed loop control simulation. A cascade control architecture is designed for the system, the outer loop is controlled by a robust passivity-based controller (RPBC) and the inner loop is controlled by an optimization method. The control algorithm provides knee angle tracking with an RMS error of 0.07 degrees. The research contributes to the field of prosthetics by showing that it is possible to find effective closed loop control algorithm for a newly proposed hydraulic knee prosthesis. The simulations demonstrate the efficiency of RPBC's ability to control …

The Synthesis And Characterization Of Multifunctional Nanoparticles Of Elastin-Like Polypeptides For Theranostic Applications, James T. Cole

ETD Archive

Theranostics is a promising field that aims to combine therapeutics and diagnostics into single multifunctional formulations. This field is driven by advancements in nanotechnology and specifically in the creation of multifunctional nanoparticles capable of providing the necessary functionalities. Elastin-like polypeptides (ELPs) are a class of environmentally responsive biopolymers that are known to undergo a transition in response to various stimuli. The organic nature of ELPs along with the ability to control their design at the gene level and the aforementioned responsive behavior make them a promising candidate for use in theranostic systems. The system presented here is one of the …

Development Of Robust Control Techniques Towards Damage Identification, Ryan J. Madden

ETD Archive

Robust control techniques have enabled engineers to create uncertain models which are able to describe any differences between the model and experimental system with uncertainties defined as a combination of exogenous inputs and plant perturbations. Subsequently, robust model validation techniques arose to provide a guarantee that the uncertain model is able to recreate all observed experimental data. As a result, the complete model set is robust to any model inaccuracies or external noise. At the same time, the technique of model-based identification was developed in the robust control framework to identify the dynamics resulting from unmodeled or under-modeled components in …

Pure And Binary Adsorption Of Methane And Nitrogen On Silicalite, Prahar S. Vaidya

ETD Archive

Separation processes comprise a large portion of the activity in the chemical and petrochemical industries. For the chemical, petroleum refining, and materials processing industries as a group, separation processes are considered to be critical. Almost all the applications of chemical industries involves mixtures, so innovation in separation technology not only enhances productivity and global competitiveness of U.S. industries, but is also critical for achieving the industrial energy and waste reduction goals. Traditionally, air separation to produce nitrogen and oxygen and to separate nitrogen from methane was practiced by cryogenic distillation, which involved expensive high pressure units and large requirement of …

Decitabine-Loaded Nanogel Treatment To Reverse Cancer Drug Resistance, Samantha A. Cramer

ETD Archive

Cancers in which epigenetic changes, such as hypermethylation of DNA, lead to drug resistance cause the cancer to become unresponsive to existing chemotherapeutic treatments. The epigenetic drug – 5-aza-2’-deoxycytidine (decitabine, DAC) – is a potent hypomethylating agent, but its effect is transient due to its instability. Previous studies have shown that loading DAC into nanogel significantly enhances its antiproliferative effect (compared to DAC in solution) in drug-resistant breast cancer cells (MCF-7/ADR). Further, the previous studies demonstrated changes in the membrane lipid profile of resistant cells following treatment with DAC either as solution or in nanogels. The objective of the present …

Intelligent Voice Activated Home Automation (Iva), Mrunal Dipakkumar Bhatt

ETD Archive

This thesis presents the design of an original Intelligent Home Automation Architecture. My work was divided in two phases. The first portion was dedicated to acquiring a thorough understanding of the most successful and diffused Home-Automation commercial architectures. During this phase, I intended to gain a deep appreciation for the variety of organizations, capabilities, limitations, and potential areas of growth of the existing Home-Automation leading systems. In order to acquire this knowledge, I had to use a reverse engineering approach. The reason for using this methodology arises from the fact that all the products considered in this study are commercially …

Experimental Investigation Of Turbulent Flow Induced By New-Generation Wind Fences With Multi-Scale Fractal Structure, Sarah M. Mcclure

ETD Archive

Understanding and controlling atmospheric boundary-layer flows with engineered structures, such as porous wind fences or windbreaks, has been of great interest to the fluid mechanics and wind engineering community. Previous studies found that the regular mono-scale grid fence of 50% porosity and a bottom gap of 10% of the fence height are considered to be optimal over a flat surface. Significant differences in turbulent flow structure have recently been noted behind multi-scale fractal wind fences, even with the same porosity. In this study, wind-tunnel tests on the turbulent flow and the turbulence kinetic energy transport of 1D and 2D multi-scale …

Assembly Level Clock Glitch Insertion Into An Xmega Mcu, Nigamantha Gopala Chakravarthi

ETD Archive

This thesis proposes clock-glitch fault injection technique to inject glitches into the clock signal running in a microcontroller unit and studying its effects on different assembly level instructions. It focusses mainly on the effect of clock glitches over the execution, sub-execution and pre-execution cycles of the test instructions and also finds the delay between the actual position of glitch insertion and the trigger being set for the glitch insertion. The instructions used in this work are provided by Atmel which classifies them according to their type of operation. These instructions are here further grouped depending on the number of clock …

State Estimation Of Glucose And Insulin Dynamics, Morgan Nicholas Miller

ETD Archive

Process simulation and state estimation have very important applications in chemical engineering as well as the biomedical field. Diabetes is a rapidly growing disease in the United States with 29 million people already diagnosed. The estimation of glucose and insulin concentration in patients is necessary in order to effectively treat diabetes. The Bergman Minimal Model is a popular process model that is used to simulate glucose and insulin dynamics. A simulation of this model was created based on estimated parameters for the model from historical data. This thesis investigated the estimation of glucose concentration, insulin concentration, and effect of active …

Field Observation Of Installation And Performance Of Repair Materials, Larisa Diana Susinskas

ETD Archive

The state of Ohio is in a region that commonly experiences drastic changes in weather. States with similar climates are susceptible to pavement cracking and failures due to the frequent or extreme freeze-thaw cycles. Freeze-thaw cycles, paired with de-icing chemicals that are frequently placed on roadways during the winter months will most likely lead to pavement cracks and failure. Ohio Department of Transportation (ODOT) routinely repairs and replaces sections of concrete roadways and bridge decks. Therefore, ODOT is seeking durable, cost-effective materials to repair smaller pavement failures.

The purpose of this study is to determine which high performance repair materials …

Specification Recommendation For Use Of High Performance Repair Material, Jennifer Woods

ETD Archive

The State of Ohio and the Ohio Department of Transportation (ODOT) have sought out ways to extend the life of the repair materials used by their construction crews, specifically, using high performance repair materials for the purposes of patching worn down or cracked sections of highways and bridge decks. Ohio is known for its frequent changes in weather, with freeze-thaw cycles occurring multiple times throughout the year. These cycles affect the lifespan of the repair material and create more maintenance for the DOT. Products that combat this problem were chosen, installed and examined over a year period to determine which …

Effects Of Digestate, Magnesium Sulfate, And Dipotassium Hydrogen Phosphate/Potassium Dihydrogen Phosphate On Microalga, Scenedesmus Dimorphus, Zhuohui Joe He

ETD Archive

Digestate (D), the remaining substance after anaerobic digestion of a biodegradable feedstock, is rich in inorganic contents, which makes it a good candidate for growing algae for biofuel production. Previous studies showed digestate at around 1.25% to 1.75% (v/v) dilution is suitable for algae growth. In this study, magnesium sulfate (MgSO4) and dipotassium hydrogen phosphate/potassium dihydrogen phosphate (K-P) were added to diluted digestate growth media. Two sets of experiments were conducted in batch reactor mode to identify the digestate (D), magnesium sulfate (MgSO4) and dipotassium hydrogen phosphate/potassium dihydrogen phosphate (K-P) concentrations that would optimize the algae growth. Algae growth parameters, …

The Response Of An Ellipsoidal Colloid Particle In An Ac Field, Cornelius Adebowale Obasanjo

ETD Archive

The quest for new smart materials with engineered properties and desired functionalities has driven scientists into the domain of nanotechnology over the past 30 years. Particles with anisotropic properties as a result of their geometry, chemical patterning or surface functionality have been envisioned as building blocks for advanced materials. By tuning the anisotropic interactions engendered by anisotropic particles, one potentially could manipulate the dynamic pathways for assembly.

The work described in this thesis considers the response of an ellipsoidal colloid particle to a nearby AC electrode polarized at ~0.1 – 4 kV/m and ~0.1 – 3 kHz. The ellipsoidal particle, …

The Behavior Of Simply Supported Plates Under Extreme Shear Loading, Mhd Ammar Hafez

ETD Archive

Steel plates are planar structural elements with one dimension significantly smaller than the others. These elements may fail due to either material yielding or buckling. Buckling is a sudden failure mode, which is not desirable in structural engineering applications. Buckling is called an “elastic buckling” when it happens before material yielding, and is termed as “plastic buckling” if it happens after material yielding. The focus of this thesis is on shear plates, which are plates that are primarily subjected to shear loads. Several studies were conducted to increase the elastic buckling capacity of plates by adding stiffeners to plates. However, …

A Simulation And Experimental Study Of Active Disturbance Rejection For Industrial Pressure Control, Xiaoxu Li

ETD Archive

The quality of control loop is very important in hydraulic machineries, where pressure must be accurately regulated in the presence of various disturbances. Proportional-Integral-Derivative (PID) control has dominated the industry for a long time and it is by far the most popular general purpose controller for pressure control. The purpose of this study is to conduct a simulation and experimental study comparing PID with an emerging new technology, namely active disturbance rejection control (ADRC). For the purpose of this study, an experimental testbed similar to those used in industry settings is used; its mathematic model is derived and used in …

Characterization Of Performance Of A 3d Printed Stirling Engine Through Analysis And Test, Julie Vodhanel

ETD Archive

This thesis involves the fusion of two technologies, Stirling engines and additive
manufacturing. The project began by building a Stirling engine primarily out of 3D printed parts. Methods to measure the power output were designed and built with a combination of 3D printed and off the shelf parts. The Stirling engine was tested to see if there was a correlation to analysis results, and a regenerator was installed to determine the effect on performance for this relatively low temperature engine. Finally, variations in test operation and the use of heat sinks were used to find a combination that will allow …

Design And Production Of A Hydrogel Forming Polypeptide: Engaging High School Students In Protein Design, James K. Deyling

ETD Archive

Bioinks are a class of hydrogel that have the potential to be the ink used in the creation of printed organs, connective tissue, and other important structures within the body. One class of material that may be a suitable bioink hydrogel is elastin-like polypeptides (ELPs), which are synthetic biopolymers inspired by the naturally existing connective tissue elastin. ELPs consist of a repeat pentapeptide sequence (GXGVP)n, where X is any of the 20 naturally existing amino acids other than proline. These biomolecules are capable of exhibiting environmental responsiveness when exposed to certain stimulus such as salt concentration, temperature, and pH, depending …