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Full-Text Articles in Engineering
Life Behind Glass: Bioreactor Studies On The Salt-Water Adaptation Of Scenedesmus Dimorphus, Joshua Hartranft, Alex Fedai, Sahar Ataya
Life Behind Glass: Bioreactor Studies On The Salt-Water Adaptation Of Scenedesmus Dimorphus, Joshua Hartranft, Alex Fedai, Sahar Ataya
Undergraduate Research Posters 2016
Algae has considerable promise as source for liquid biofuel because of high productivity and because algae farms do not compete with food crops for arable land. Freshwater algae is preferred over saltwater algae because of the higher lipid content in the former. Unfortunately, freshwater algae “farms” would require a vast amount of fresh water, and given the scarcity of fresh water, this is not a viable long-term solution. Therefore, the adaption of a fresh-water species of algae to a salt-water environment is a potential solution. In this study, it was shown that the growth rate of the freshwater algae S. …
Glycerolipid Analysis Of Adaptation To Saline Changes In The Culture Conditions Of Algae, Scenedesmus Dimorphus, By Gc-Ms, Tyler Fitzgerald, Satya Girish Chandra Avula, Chandana Mannem
Glycerolipid Analysis Of Adaptation To Saline Changes In The Culture Conditions Of Algae, Scenedesmus Dimorphus, By Gc-Ms, Tyler Fitzgerald, Satya Girish Chandra Avula, Chandana Mannem
Undergraduate Research Posters 2016
Since fossil fuels are decreasing over time an alternative energy source will be soon required. The algae, Scenedesmus dimorphus, grows in freshwater and is known for its fast growth of glycerolipid content which is used for biodiesel production. After the algae is grown in optimal conditions, the released fatty acids and glycerolipids are transformed into fatty acid methyl esters (FAMEs) which are used as biodiesel. The FAMEs were quantitatively determined by gas chromatography mass spectrometry (GC-MS) to determine the total glycerolipid content in the different algae samples. The samples that were analyzed include freshwater controls and saline adapted samples. Analysis …
Design And Fabrication Of A Microfluidic Device Using A 3d Printer, Aaron Smith
Design And Fabrication Of A Microfluidic Device Using A 3d Printer, Aaron Smith
Undergraduate Research Posters 2016
The goal of this work was to design and implement a microfluidic mixer-based chemical reactor using a 3-D printer. Microfluidic devices are very useful for processes that use expensive reactants or require a high level of control, and we hypothesize that the ability to develop a prototype using a 3-D printer would lower their costs and help overcome some of the limitations of soft-lithography based devices. One-level and two-level designs were made using SolidWorks® software, and various stages of the model were printed on Objet® and FDM® printers. The Objet printer offers the advantage of printing a prototype using a …
Scalable Assembly Of Nanoparticles Onto Templated Substrates, John Juchnowski
Scalable Assembly Of Nanoparticles Onto Templated Substrates, John Juchnowski
Undergraduate Research Posters 2016
Anisotropic nanoparticles, such as carbon nanotubes and noble metal nanorods, have excellent electrical, mechanical, and thermal properties. This work examined techniques for the nanopatterning of silicon substrates for the subsequent deposition of anisotropic nanoparticles in order to exploit their properties in macroscopic applications. Argon-ion-sputter induced rippling of Si (100) as well as a microparticle mask were examined as methods for templating a silicon substrate. For the ion-sputter
Light Scattering Characterization Of Elastin-Like Polypeptide Trimer Micelles, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Light Scattering Characterization Of Elastin-Like Polypeptide Trimer Micelles, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Undergraduate Research Posters 2016
Elastin-Like Polypeptides (ELP) can be used to form thermo-reversible vehicles for drug delivery systems. The ELP nanoparticles are composed of three-armed star polypeptides. Each of the three arms extending from the negatively charged foldon domain includes 20 repeats of the (GVGVP) amino acid sequence. The ELP polymer chains are soluble at room temperature and become insoluble at the transition temperature (close to 50 oC), forming micelles. The size and shape of the micelle is dependent on the temperature and the pH of solution, along with the concentration of the Phosphate Buffered Saline (PBS) solvent. The technique of Depolarized Dynamic Light …
Light Scattering Study Of Mixed Micelles Made From Elastin-Like Polypeptide Linear Chains And Trimers, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Light Scattering Study Of Mixed Micelles Made From Elastin-Like Polypeptide Linear Chains And Trimers, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Undergraduate Research Posters 2016
Temperature sensitive nanoparticles (E20F) were generated from a construct of three chains of Elastin- Like Polypeptides (ELP) linked to a negatively charged foldon domain. This ELP system was mixed at different ratios with a single linear chain of ELP (H40L) which was deprived of the foldon domain. The mixed system is soluble at room temperature and at a transition temperature will form swollen micelles with the hydrophobic linear chains hidden inside. This system was studied using Depolarized Dynamic Light Scattering (DDLS) and Static Light Scattering (SLS) to model the size, shape, and internal structure of the mixed micelles. The mixed …
Identifying Patterns Of Stress Through Biological Markers, Kristyn Oravec
Identifying Patterns Of Stress Through Biological Markers, Kristyn Oravec
Undergraduate Research Posters 2016
technique, the angle of incidence of the ion beam was 67° from the surface normal,
High-Throughput Assessment Of Developmental Stages Of Nscs Via Promoter-Reporter Assay System Using Recombinant Lentiviruses, Emily Serbinowski, Pranav Joshi, Kyeong Nam Yu, Yana Sichkar
High-Throughput Assessment Of Developmental Stages Of Nscs Via Promoter-Reporter Assay System Using Recombinant Lentiviruses, Emily Serbinowski, Pranav Joshi, Kyeong Nam Yu, Yana Sichkar
Undergraduate Research Posters 2016
Many drugs and chemicals currently available have not been fully evaluated for their toxic effects on the developing brain. Expensive and low-throughput in vivo studies are still being used to evaluate developmental neurotoxicity (DNT). Thus, there is a need to develop an in vitro assay system which is economically feasible and high- throughput. Among various cellular models used for in vitro assay, human neural stem cells (NSCs) are highly desired due to their ability to self-renew and differentiate into neurons, astrocytes and oligodendrocytes. In vitro assessment of developmental stages (proliferation and differentiation) of human NSC is highly important to predict …
Layer-By-Layer Printing Of Alginate For Cancer Cell Migration Assays, Yana Sichar, Alexander Roth, Emily Serbinowski, Kyeong Nam Yu
Layer-By-Layer Printing Of Alginate For Cancer Cell Migration Assays, Yana Sichar, Alexander Roth, Emily Serbinowski, Kyeong Nam Yu
Undergraduate Research Posters 2016
Rapid assessment of the invasion potential of various cancers in three-dimensional (3D) cell culture via layer-by-layer printing of cells encapsulated in hydrogels has been studied. Microarray bioprinting technology on microwell chips has been explored to create 3D cancer-like tissue structures and study cancer cell migration. Alginate, a negatively charged biopolymer, forms hydrogels via ionic crosslinking. Oxy-methacrylated alginate (OMA) is polymerized via near-ultraviolet light in the presence of photoinitiators. Our goal is to demonstrate rapid creation of cancer tissuelike structures via microarray 3D-bioprinting and develop a high-throughput, 3D cancer cell migration assay. To achieve this goal, layer-by-layer cell culture conditions were …
Design And Development Of A Microfluidic Platform To Induce Mechanical Stimuli On Growing Axons, Edward Jira, Erin Tesny
Design And Development Of A Microfluidic Platform To Induce Mechanical Stimuli On Growing Axons, Edward Jira, Erin Tesny
Undergraduate Research Posters 2016
In cases of injury and degenerative diseases, stresses can be placed on individual nerve cells in the human body that greatly, and often permanently, impact the function of the human nervous system. In order to treat these it is imperative to better understand the effects these stresses can have on the development and function of individual neurons. Because of the logistical difficulties of studying cells in-vitro, it has become increasingly popular to study neuronal cells in vivo using microfluidic devices. Current studies focus mainly on the impact of chemical signals on neurons. The focus of this study however, is to …
Effect Of Salt Concentration On The Composition Of Elastin-Like Polypeptides In The Condensed Coacervate Phase, Louise L. Beckstrom, Adam Maraschy, Daniel P. Miller
Effect Of Salt Concentration On The Composition Of Elastin-Like Polypeptides In The Condensed Coacervate Phase, Louise L. Beckstrom, Adam Maraschy, Daniel P. Miller
Undergraduate Research Posters 2016
Elastin-Like Polypeptides (ELPs) are thermo-responsive polymers which could potentially be used as vehicles for drug delivery. The nanoparticle vehicles are called micelles and the basic structure is made of ELP-foldon. This ELP-foldon has a head group (foldon) that is hydrophilic and three tails (ELP) that are hydrophobic. Above a certain temperature, the transition temperature (Tt), the hydrophobic tails aggregate together to form spheres with the hydrophilic headgroups on the outside. Inside the micelles, linear ELP and drugs can be captured. Although micelles can form without linear ELP, they are bigger when it is present. At lower temperatures the ELPs are …
Designing Genes That Encode Proteins For Biomedical Applications, Isaiah Traben
Designing Genes That Encode Proteins For Biomedical Applications, Isaiah Traben
Undergraduate Research Posters 2016
DNA is a crucial component of all known life. It encodes in genes the structure of the proteins necessary to perform many of the functions in a cell. Proteins are biological polymers consisting of a chain of amino acids. The specific sequence of the amino acids determines the structure and therefore function of the protein. The sequence of the amino acids of a protein is coded in DNA via triplets of the nucleotide bases known as codons, which each can represent only one amino acid. However, an amino acid can be represented by more than one codon, so there are …
Design And Characterization Of Protein-Based Bioink, Ryan Martin, James Deyling
Design And Characterization Of Protein-Based Bioink, Ryan Martin, James Deyling
Undergraduate Research Posters 2016
Elastin-like polypeptide (ELP) based, temperature responsive triblocks are an attractive alternative to current cell encapsulation hydrogels (bioinks) used in bioprinting, due to their natural physiological properties and their potential for higher cell viability. Many cell encapsulating hydrogels in current use, require UV light to initiate crosslinking which can be damaging to the encapsulated cells. Other materials irreversibly gel with a change in temperature potentially clogging the bioprinting instruments. ELP based hydrogels utilize temperature dependent gelation, but gel reversibly. Elastin is a natural material in human tissue which many protein scaffolds are made of. We are studying an ELP triblock consisting …
Explaining Simulator Sickness, Jonathan Cohen
Explaining Simulator Sickness, Jonathan Cohen
Undergraduate Research Posters 2016
Subjects who participate in driving simulation experiments often experience symptoms similar to motion sickness, called “simulator sickness.” However, the exact cause of these symptoms is unknown, which makes it difficult to predict whether a subject will experience them, or to warn them of the likelihood of experiencing those symptoms. A possible relationship between motion sickness and simulator sickness has been conjectured, based on the similarity of the symptoms, but not proven. In this study, we examined whether subjects in CSU simulator experiments who reported a history of motion sickness were more likely to experience the symptoms of simulator sickness. We …
Privacy-Aware Human Tracking Using Kinect And Android Smart Watches, Mudenda Martin Bbela
Privacy-Aware Human Tracking Using Kinect And Android Smart Watches, Mudenda Martin Bbela
Undergraduate Research Posters 2016
Using the Microsoft Kinect® in conjunction with an Android Wear device, this project aims to design a Privacy Aware 3D motion tracking application with haptic feedback functionality used to reduce prevalence of Back Injuries in Caregivers. The System will use a registration method to ensure the caregiver is both uniquely tracked and abstract from most of the information used by the application.
Characterization Of Aerospike Nozzle Flows, Donald Grimes, Maggie Kolovich, Justin Flaherty, Umesh Balar, Hitarthsinh Chudasama
Characterization Of Aerospike Nozzle Flows, Donald Grimes, Maggie Kolovich, Justin Flaherty, Umesh Balar, Hitarthsinh Chudasama
Undergraduate Research Posters 2016
Aerospike nozzles possess many qualities that make them more desirable and efficient than conventional bell-shaped rocket nozzles. Aerospike nozzles have been studied since the 1960s, but problems and limitations with experimentation often led to abandoning further efforts on aerospike nozzles and implementing much more familiar bell-shaped nozzles. In fact, aerospike nozzles have yet to be used in flight—they have only undergone ground testing. The goal of our research is to develop multiple additively manufactured aerospike nozzles and characterize the flow experimentally, numerically, and computationally. Schlieren photography and Particle Image Velocimetry (PIV) are used to experimentally characterize the flow, ANSYS CFD …
Gpu Assisted High Performance Rsa Encryption, Zhe Zhao, Alec Mcgrady
Gpu Assisted High Performance Rsa Encryption, Zhe Zhao, Alec Mcgrady
Undergraduate Research Posters 2016
GPU has become highly popular due to its parallel computing ability. It accelerates operations in large scale. Many applications associate with intensive computations. RSA cryptosystem is one of them that can benefit from its utility. The purpose of this research is to implement RSA encryption and decryption by utilizing GPU to enhance the performance of the process. Since RSA public key and private key operations actually consist of large integer multiplications in a finite field, this research explores the efficient algorithms and implementations of the high performance GPU large integer multiplications. Our work has been implemented on the following three …
Computing Human Arm Stiffness For The Purpose Of Robotic Simulation, Nicholas Gehler, Philip Sesco
Computing Human Arm Stiffness For The Purpose Of Robotic Simulation, Nicholas Gehler, Philip Sesco
Undergraduate Research Posters 2016
To replace a human during experiments, we've calculated the endpoint stiffness of a human arm to be simulated on a robot. The model used to calculate arm stiffness includes gravitational, short-range muscle, and muscle force-moment arm stiffnesses. The parameters of this model were estimated using data from the open source musculoskeletal MATLAB model, Dynamic Arm Simulator. The model will be used by a Barrett Proficio robot to simulate the stiffness of a human arm. The purpose of this human arm simulation is for experimentation during the development of a force sensing feedback system for functional electrical stimulation (FES). A robot …
Ground Reaction Force Measurement With A Piezoelectric Insole, Mohamad Khattab
Ground Reaction Force Measurement With A Piezoelectric Insole, Mohamad Khattab
Undergraduate Research Posters 2016
The objectives of this research project are to design and build an instrumented shoe to measure the vertical ground reaction force (GRF) associated with a person walking or running. Sensor outputs are calibrated to actual GRF with an artificial neural network. Currently, GRF measurements require special equipment such as force plates or scientific treadmills. A force plate measures GRF over a limited area. A shoe insole fitted with sensors was identified as a good solution that allows free-range walking over arbitrary surfaces. Piezoelectric film sensors were chosen due to their low cost, flexibility and for being self-powered. Eight sensors were …
Bent Knee Adaptor For Experimental Testing Of Prostheses, Santino Bianco
Bent Knee Adaptor For Experimental Testing Of Prostheses, Santino Bianco
Undergraduate Research Posters 2016
Novel prosthetic devices must undergo testing as part of their development. Testing with amputees is problematic at the development stage due to safety and administrative burdens. A bent-knee adaptor allows able-bodied individuals to wear a prosthesis and facilitate prototype testing. An existing bent-knee adaptor was used as a basis to design an improved device. The existing adaptor did not preserve alignment between thigh and prosthesis, resulting in unnatural walking. 3D scanning and printing technologies were used to design the new adaptor. Solid modeling was used to verify that the new design would withstand the loads associated with walking. The device …
Correcting Reaching Movements Using Force Sensors And Robot Simulation, Megan Carrick
Correcting Reaching Movements Using Force Sensors And Robot Simulation, Megan Carrick
Undergraduate Research Posters 2016
People who have suffered high spinal cord injuries are unable to move their limbs. Functional electrical stimulation (FES) activates paralyzed muscles by electrical current and is a way to restore some function to a paralyzed arm. This research was conducted to develop a way for a caregiver to correct reaching movements to a person with paralyzed arms. We asked participants to take part in this study to help obtain data to test the learning feedback system. We represented a paralyzed arm with a Barrett Medical Proficio robot. The robot is programmed to reach out and purposely miss a target. The …
Prediction Of Muscle Torque Production For The Control Of A Paralyzed Arm, Andrew Aylward, Kyra Ruby
Prediction Of Muscle Torque Production For The Control Of A Paralyzed Arm, Andrew Aylward, Kyra Ruby
Undergraduate Research Posters 2016
Functional electrical stimulation (FES) is a method of restoring function to muscles using electrical pulses delivered through an implanted controller. FES has shown potential for enabling people with high spinal cord injuries to perform basic reaching motions essential to everyday tasks. In order to determine the necessary muscle activations an FES neuroprosthesis must produce to cause a desired arm motion, we must first be able to predict the amount of torque that muscles can produce at each joint. The torque production varies depending on the state of the system. Gaussian Process Regression models were trained with data gathered using a …
Wrist-Mounted Feedback System: Monitoring Force And Torque In Six Degrees Of Freedom, Christopher Schroeck
Wrist-Mounted Feedback System: Monitoring Force And Torque In Six Degrees Of Freedom, Christopher Schroeck
Undergraduate Research Posters 2016
This project developed a wrist-mountable, six Degrees of Freedom (DoF) feedback system that monitors force and torque. This system is designed to be used by nontechnical operators to correct movements of a paralyzed arm under the control of a functional electrical stimulation (FES) neuroprosthesis. The resulting corrections are recorded and processed by additional programs so as to improve the accuracy of future movements controlled by the FES system. The feedback system was tested on a robotic arm that is programmed to simulate a paralyzed human's arm. These tests checked the sensor for accuracy, reliability, durability, ease of use, and stability. …