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Full-Text Articles in Engineering
Code To Combustion: Cnc Rotor Replication Using Cam, Luis Luna
Code To Combustion: Cnc Rotor Replication Using Cam, Luis Luna
Publications and Research
In the current landscape, computer-aided design (CAD) and computer numerical control (CNC) technologies have greatly enhanced manufacturing processes, allowing rapid and high-precision production. This project will focus on recreating a Wankel engine rotor, using SolidWorks for design and Mastercam for Computer-Aided Manufacturing (CAM) simulations. The process begins with SolidWorks, which is used for a template of a high-precision rotor model. Mastercam is then utilized for the CAM programming, allowing for the creation of intricate tool paths and tool usage simulations. This approach is vital for complex objects like the Wankel engine rotor, which demands high precision. The primary objective of …
Renal Specific Rnai Delivery By Fibrillar Nanoparticle Excipients, Sam Wong
Renal Specific Rnai Delivery By Fibrillar Nanoparticle Excipients, Sam Wong
Dissertations, Theses, and Capstone Projects
RNA interference (RNAi) is a powerful tool to manipulate the phenotype of an organism by silencing the expression of specific genes and is viewed as a highly promising platform for treating undruggable targets and disorders where small molecule drugs and antibodies would fail. However, development of RNAi based therapies has faced major barriers including cellular and tissue-specific uptake of the Small Interfering RNA (siRNA). Utilizing different nanoparticles as RNAi excipients, cellular uptake and gene silencing potency can be greatly improved. The research in Dr. McDevitt groups has fibrillar carbon nanotubes (CNT) as carriers for siRNA for gene silencing in vitro …