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Articles 1 - 30 of 42
Full-Text Articles in Engineering
Minimalistic Peptide-Based Supramolecular Systems Relevant To The Chemical Origin Of Life, Daniela Kroiss
Minimalistic Peptide-Based Supramolecular Systems Relevant To The Chemical Origin Of Life, Daniela Kroiss
Dissertations, Theses, and Capstone Projects
All forms of life are based on biopolymers, which are made up of a selection of simple building blocks, such as amino acids, nucleotides, fatty acids and sugars. Their individual properties govern their interactions, giving rise to complex supramolecular structures with highly specialized functionality, including ligand recognition, catalysis and compartmentalization. In this thesis, we aim to answer the question whether short peptides could have acted as precursors of modern proteins during prebiotic evolution. Using a combination of experimental and computational techniques, we screened a large molecular search space for peptide sequences that are capable of forming supramolecular complexes with adenosine …
The Water/Energy Nexus: Climate, Consumption And Ecosystem Services, Hildegaard D. Link
The Water/Energy Nexus: Climate, Consumption And Ecosystem Services, Hildegaard D. Link
Dissertations, Theses, and Capstone Projects
Water and energy are drivers of living systems. This work provides an assessment of the Water Energy Nexus in the United States, comparing the well-watered north-east and the arid west. Electric grid systems are most stressed on hot summer afternoons. Grid stress can lead to cascading failures of electricity, water and wastewater treatment systems. (Zimmerman, 2017) Water for power generation and/or water supply depend on ecosystem services. The ecosystem services and resource trade-offs embedded in provision of a watt of power and an ounce of potable water, however, have yet to be comprehensively enumerated nor have the cost relationships been …
Renal Specific Rnai Delivery By Fibrillar Nanoparticle Excipients, Sam Wong
Renal Specific Rnai Delivery By Fibrillar Nanoparticle Excipients, Sam Wong
Dissertations, Theses, and Capstone Projects
RNA interference (RNAi) is a powerful tool to manipulate the phenotype of an organism by silencing the expression of specific genes and is viewed as a highly promising platform for treating undruggable targets and disorders where small molecule drugs and antibodies would fail. However, development of RNAi based therapies has faced major barriers including cellular and tissue-specific uptake of the Small Interfering RNA (siRNA). Utilizing different nanoparticles as RNAi excipients, cellular uptake and gene silencing potency can be greatly improved. The research in Dr. McDevitt groups has fibrillar carbon nanotubes (CNT) as carriers for siRNA for gene silencing in vitro …
Quorum Blockchain Stress Evaluation In Different Environments, Daniel P. Mera
Quorum Blockchain Stress Evaluation In Different Environments, Daniel P. Mera
Student Theses
In today’s world, the Blockchain technology is used for different purposes has brought an increment in the development of different Blockchain platforms, services, and utilities for storing data securely and efficiently. Quorum Blockchain, an Ethereum fork created by JPMorgan Chase, has placed itself in one of the widely used, efficient and trustful Blockchain platforms available today. Because of the importance which Quorum is contributing to the world, it is important to test and measure different aspects of the platform, not only to prove how efficient the software can be but as well as to have a clear view on what …
Fashion Merchandising: An Augmented Reality, Naeha A. Sayed
Fashion Merchandising: An Augmented Reality, Naeha A. Sayed
Dissertations, Theses, and Capstone Projects
There is a continuous and constant transformation in the field of Augmented Reality (AR), both in the Retail, and the Manufacturing sector. It has started to influence everything from fashion runway shows to online shopping. Consumers dynamics have shifted in the fashion industry, the ways becoming more dominant than the old observant ones- the simple buying experience no longer satisfies them. Due to the emergence of the new digital platforms and technological enhancements, the consumers are looking for more- be it a more exciting buying experience or more user interaction or more enhanced products. This technological change starts with the …
Synthesis And Characterization Of Dielectric And Multiferroic Nanocrystalline Transition Metal Oxide Materials And Nanocomposites, Frederick A. Pearsall
Synthesis And Characterization Of Dielectric And Multiferroic Nanocrystalline Transition Metal Oxide Materials And Nanocomposites, Frederick A. Pearsall
Dissertations, Theses, and Capstone Projects
Nanocrystalline transition metal oxides with unique chemical, physical, magnetic and dielectric properties have very broad applications, ranging from photocatalysis, capacitor energy storage and 4-state memory. Frequency stable, high permittivity nanocomposite capacitors produced under mild processing conditions offer an attractive replacement to MLCCs derived from conventional ceramic firing. In one project reported herein, 0-3 nanocomposites were prepared using BaTiO3 (barium titanate, BTO) nanocrystals, suspended in a poly(furfuryl alcohol) matrix, resulting in a stable, high effective permittivity, low and stable loss dielectric. Effective medium approximations were used to compare this with similar nanocomposite systems. The use of synthesized BTO nanocrystal photocatalysts …
A Purely Defeasible Argumentation Framework, Zimi Li
A Purely Defeasible Argumentation Framework, Zimi Li
Dissertations, Theses, and Capstone Projects
Argumentation theory is concerned with the way that intelligent agents discuss whether some statement holds. It is a claim-based theory that is widely used in many areas, such as law, linguistics and computer science. In the past few years, formal argumentation frameworks have been heavily studied and applications have been proposed in fields such as natural language processing, the semantic web and multi-agent systems. Studying argumentation provides results which help in developing tools and applications in these areas. Argumentation is interesting as a logic-based approach to deal with inconsistent information. Arguments are constructed using a process like logical inference, with …
Using Transfer Learning In Network Markets, Kai Cai
Using Transfer Learning In Network Markets, Kai Cai
Dissertations, Theses, and Capstone Projects
Mechanism design is the sub-field of microeconomics and game theory, which considers agents have their own private information and are self-interested and tries to design systems that can produce desirable outcomes. In recent years, with the development of internet and electronic markets, mechanism design has become an important research field in computer science. This work has largely focused on single markets. In the real world, individual markets tend to connect to other markets and form a big “network market”, where each market occupies a node in the network and connections between markets reflect constraints on traders in the markets. So, …
Efficient Private Information Retrieval, Konstantinos Nikolopoulos
Efficient Private Information Retrieval, Konstantinos Nikolopoulos
Dissertations, Theses, and Capstone Projects
A vast amount of today's Internet users' on line activities consists of queries to various types of databases. From traditional search engines to modern cloud based services, a person's everyday queries over a period of time on various data sources, will leave a trail visible to the query processor, which can reveal significant and possibly sensitive information about her. Private Information Retrieval (PIR) algorithms can be leveraged for providing perfect privacy to users' queries, though at a restrictive computational cost. In this work, we consider today's highly distributed computing environments, as well as certain secure-hardware devices, for optimizing existing PIR …
A Dynamic Risk Management Framework For Water And Environmental Sustainability, Arun Ravindranath
A Dynamic Risk Management Framework For Water And Environmental Sustainability, Arun Ravindranath
Dissertations and Theses
The risks and vulnerabilities facing reservoir systems in river basins shift dynamically over time and space. These risks involve regime changes and shifts, throughout which one observes the transition of water availability from prolonged dry periods to prolonged wet periods. Ensuring reliability of water supply under these hydrological regime shifts involves understanding how these regime shifts can be identified, characterized, and quantified. This dissertation describes a dynamic risk management (DRM) framework for water management at the basin level whose main features are (1) a system of updating risk assessments and policy recommendations on a yearly basis, where the risk assessments …
A Microfluidic Tissue Array (Μfta) For Personalized Medicine Using Tumor Biopsies, A.H. R. Ahmed
A Microfluidic Tissue Array (Μfta) For Personalized Medicine Using Tumor Biopsies, A.H. R. Ahmed
Dissertations and Theses
Cancer is recognized as a complex disease with both genetic and epigenetic drivers that can vary from one individual to another. While very early research into cancer treated it as a clonal malfunction that could originate from as small as a single deregulated cell, the disease itself manifests itself with several more complexities beyond tumorigenic cells only. The tumor microenvironment itself – from the extracellular matrix to stromal cells - cooperate with tumor cells in a symbiotic manner towards metastatic progression. Clinical studies have provided more information regarding the degree of individualization possible, such that patients with similar genetic makeup …
Designing An On-Demand Dynamic Crowdshipping Model And Evaluating Its Ability To Serve Local Retail Delivery In New York City, Shirin Najaf Abadi
Designing An On-Demand Dynamic Crowdshipping Model And Evaluating Its Ability To Serve Local Retail Delivery In New York City, Shirin Najaf Abadi
Dissertations and Theses
Nowadays city mobility is challenging, mainly in populated metropolitan areas. Growing commute demands, increase in the number of for-hire vehicles, enormous escalation in several intra-city deliveries and limited infrastructure (road capacities), all contribute to mobility challenges. These challenges typically have significant impacts on residents’ quality-of-life particularly from an economic and environmental perspective. Decision-makers have to optimize transportation resources to minimize the system externalities (especially in large-scale metropolitan areas). This thesis focus on the intra-city mobility problems experienced by travelers (in the form of congestion and imbalance taxi resources) and businesses (in the form of last-mile delivery), while taking into consideration …
Unsupervised Feature Learning For Point Cloud By Contrasting And Clustering With Graph Convolutional Neural Network, Ling Zhang
Dissertations and Theses
Recently, deep graph neural networks (GNNs) have attracted significant attention for point cloud understanding tasks, including classification, segmentation, and detection. However, the training of such deep networks still requires a large amount of annotated data, which is both expensive and time-consuming. To alleviate the cost of collecting and annotating large-scale point cloud datasets, we propose an unsupervised learning approach to learn features from unlabeled point cloud ”3D object” dataset by using part contrasting and object clustering with GNNs. In the contrast learning step, all the samples in the 3D object dataset are cut into two parts and put into a …
Controlled Migration Of Retinal Progenitor Cells Within Electro-Chemotactic Fields, Shawn Mishra
Controlled Migration Of Retinal Progenitor Cells Within Electro-Chemotactic Fields, Shawn Mishra
Dissertations and Theses
Vision loss in retinal degenerative diseases is overwhelmingly attributed to damage and death of retinal photoreceptor cells. Studies in mouse retina have suggested that transplantation of isolated post-natal or stem cell-derived retinal progenitor cells (RPCs) to replace apoptotic or damaged photoreceptors may be a novel approach to restore vision. Thus far, outcomes project that the amount of restored visual response depends upon the migration of transplanted cells from insertion in the sub-retinal space to the outer nuclear layer (ONL). However, transplantation efficiency is exceedingly low – ~5% cells transplanted enter the retina – directly limiting the efficacy of the treatments. …
Wrinkling Of Membrane And Thin Film Under Torsion, Tingting Chen
Wrinkling Of Membrane And Thin Film Under Torsion, Tingting Chen
Dissertations and Theses
Membranes and thin film structures are widely used in modern technologies. Applications include solar sails and sunshields in space missions, biological membranes and flexible circuit boards. Wrinkling of membrane or a stiff film on a soft substrate may occur in either desired or unwanted patterns. This work tries to obtain some understanding on the wrinkling phenomenon and provide guidance in avoiding wrinkling or effectively controlling the wrinkle patterns.
Many works have been published about wrinkling in the thin sheets since the 20th century. However, there is no simple analytical way to systematically characterize the wrinkling in these studies. In …
The Influence Of Size And Progression Of Intra-Cerebral Hematoma On The Lateral Ventricles, Muhammad J. Ashraf
The Influence Of Size And Progression Of Intra-Cerebral Hematoma On The Lateral Ventricles, Muhammad J. Ashraf
Dissertations and Theses
Cerebrovascular diseases like intra cerebral hemorrhage are quite deadly and may disturb functioning of the brain, expanding and resulting in formation of an intra cerebral hematoma(ICH). It is imperative to comprehend how hematoma and its expansion inside the brain endangers human life. One of the influences of an ICH inside brain tissue is on the Lateral Ventricles(LV). When the hemorrhage occurs close enough to the lateral ventricles, filled with cerebrospinal fluid(CSF), it disrupts the balance of fluid in LV. A minor pressure change in LV can negatively influence the production of CSF as well as an increase in intracranial pressure. …
Electrochemical Properties Of Crystalline Polymorphs Of Mno2 In Aluminum And Zinc Metal Batteries, Subhadip Pal
Electrochemical Properties Of Crystalline Polymorphs Of Mno2 In Aluminum And Zinc Metal Batteries, Subhadip Pal
Dissertations and Theses
The widespread use of non-renewable fossil fuels has led to societal problems like global warming and climate change. Electrochemical energy storage can enable the integration of renewable energy sources that are inherently intermittent (solar, wind, etc.) into the electric grid, though major advances in cost, cycle life, and safety are necessary to have a global impact on the energy landscape. Both aluminium (Al) and zinc (Zn) metals are earth abundant, low-cost, safe, and exhibit high coulombic capacities, which make them promising electrode materials for “beyond lithium-ion” battery chemistries. However, the electrochemical feasibility and charge storage mechanisms of alternative Al and …
Gas Hold-Up Measurements In 0.3 M Diameter Bubble Column: Effect Of Electrolytes, Heber Blanco De Brand
Gas Hold-Up Measurements In 0.3 M Diameter Bubble Column: Effect Of Electrolytes, Heber Blanco De Brand
Dissertations and Theses
The present work reports the axial, radial and temporal gas hold-up profiles in a 0.3 m diameter batch bubble column using a pair of Wire Mesh Sensors and six pressure transducers.
Void Fraction Measurements In Large (0.3 M) Diameter Bubble Column Using Wire Mesh Sensor And Pressure Transducers- Effect Of Sparger, Afolabi Gabriel Ojo
Void Fraction Measurements In Large (0.3 M) Diameter Bubble Column Using Wire Mesh Sensor And Pressure Transducers- Effect Of Sparger, Afolabi Gabriel Ojo
Dissertations and Theses
The importance of the accurate temporal and spatial measurements of the two-phase flow parameters in bubble columns is very well known. The aim of this research work is to report the spatial measurements of the void fraction distribution in a 30 cm diameter cylindrical bubble column using Wire Mesh Sensor (WMS) tomography and Pressure Transducers. Pair of WMS sensors, with a 64×64 wire configuration of each sensor, were installed which are separated by a distance along the axis of the bubble column. Wire Mesh Sensors and PTs Data were collected for time-averaged and transient with a sampling frequency of 1000 …
Neuron-Glial (Ng) Interactions: A Microfluidic Examination Of Ng Emergent Responses For Repair, Tanya Singh
Neuron-Glial (Ng) Interactions: A Microfluidic Examination Of Ng Emergent Responses For Repair, Tanya Singh
Dissertations and Theses
Neuron-glia communication is crucial to the development, plasticity, and repair of the nervous system (NS). While neurons are well known to conduct electrical impulses that transfer biological information and stimuli throughout the NS, our understanding of the roles of glia continues to evolve from when the cells were largely believed to act solely for neuronal support. Recent decades of research has shown that glia can alter metabolism, conduct impulses and change phenotype for NS repair. NG interactions have, thereby, become heavily researched in varied areas of biomedical engineering, including embryogenesis, neural regeneration, growth, and intracellular synaptic activity. However, while NG …
Ict-Enabled Control And Energy Management Of Community Microgrids For Resilient Smart Grid Operation, Mahmoud Saleh
Ict-Enabled Control And Energy Management Of Community Microgrids For Resilient Smart Grid Operation, Mahmoud Saleh
Dissertations and Theses
Our research has focused on developing novel controllers and algorithms to enhance the resilience of the power grid and increase its readiness level against major disturbances.
The U.S. power grid currently encounters two main challenges: (1) the massive and extended blackouts caused by natural disasters, such as hurricane Sandy. These blackouts have raised a national call to explore innovative approaches for enhanced grid resiliency. Scrutinizing how previous blackouts initiated and propagated throughout the power grid, the major reasons are lack of situational awareness, lack of real-time monitoring and control, underdeveloped controllers at both the transmission and distribution levels, and lack …
Global Food Security Under Climate-Water-Energy Nexus, Ehsan Najafi
Global Food Security Under Climate-Water-Energy Nexus, Ehsan Najafi
Dissertations and Theses
During the last few decades, the global agricultural production has risen and technology enhancement is still contributing to yield growth. However, population growth, water and energy crisis, and extreme weather, climate change, etc. threaten the global food security. The focus of this study is to advance the understanding of the associations between crops productivity and large scale and local scale climatic variables, climate change, technology enhancement and assessing food-water-energy nexus to enhance global food security in a sustainable manner considering current available resources. As decision-makers try to improve food security, it is important to identify the impact of technology enhancement …
Understanding And Modeling Taxi Demand Using Time Series Models, Sabiheh Faghih
Understanding And Modeling Taxi Demand Using Time Series Models, Sabiheh Faghih
Dissertations and Theses
The spatio-temporal variations in demand for transportation, particularly taxis, are impacted by various factors such as commuting, weather, road work and closures, disruption in transit services, etc. Identifying the factors that influence taxi demand and understanding its dynamic provide planners with the information necessary to improve the transportation systems and also help drivers to reduce their vacant time.
This dissertation focuses on important factors affecting the demand. In the beginning, the impact of price changes on the demand is studied. Chapter One discusses how the seasonal effects and trends are removed from the demand, and then price elasticity for demand …
Improving Retrievals Of Crop Vegetation Parameters From Remote Sensing Data, Nathaniel Levitan
Improving Retrievals Of Crop Vegetation Parameters From Remote Sensing Data, Nathaniel Levitan
Dissertations and Theses
Agricultural systems are difficult to model because crop growth is driven by the strongly nonlinear interaction of Genotype x Environment x Management (G x E x M) factors. Due to the nonlinearity in the interaction of these factors, the amount of data necessary to develop and utilize models to accurately predict the performance of agricultural systems at an operational scale is large. Satellite remote sensing provides the potential to vastly increase the amount of data available for modelling agricultural systems as a result of its high revisit time and spatial coverage. Unfortunately, there have been significant difficulties in deploying remote …
Integrating Multi-Source Weather Data For Deep Learning, Haidar A. Alanbari Mr
Integrating Multi-Source Weather Data For Deep Learning, Haidar A. Alanbari Mr
Dissertations and Theses
Big Data has been playing a major role in the domain of Deep Learning applications as many companies and institutions continue to find solutions and extract certain trends in fields of climate change, weather forecasting and meteorology. This project extracts weather events data from multiple data sources that are supported by National Centers for Environmental information (NCEI) [1] and Amazon Web Services (AWS) [2]. Data sources include Next-Generation NEXRAD [3] Doppler radar reflectivity, GOES-16 [4] multi-channel satellite imagery and NCEI [1] storm events. Then, it integrates and refines data in proper formats to be fed to the open-source Detectron [5] …
Internet Of Things: Architecture And Services For Healthcare, Ankita Suvagia Ms.
Internet Of Things: Architecture And Services For Healthcare, Ankita Suvagia Ms.
Dissertations and Theses
Internet of Things (IoT) is a recent prominent collaboration of various technologies that enables spatially distributed devices (“things”) to sense, communicate and share information, thus generating a variety of applications and services in Healthcare. IoT is implemented in multiple domains like Smart city, energy and smart grid, Smart home, weather forecasting, Agriculture, Market and Transportation, Manufacturing and testing industries, Healthcare and many more. IoT serves the purpose of making tasks more efficient and productive and at the same time ensuring quality and reliability. IoT technologies provide an enabling framework for inter-connecting devices, systems, and services that go beyond Machine-to-Machine scenarios …
Investigation Of The Synthesis And Optoelectronic Properties Of Ultrasmall Cdse Quantum Dots, Megan Webster
Investigation Of The Synthesis And Optoelectronic Properties Of Ultrasmall Cdse Quantum Dots, Megan Webster
Dissertations and Theses
Traditional, or 1st generation, solar cells have a theoretical upper limit of 33% power conversion efficiency based on the thermodynamic limitation of the single p-n junction cell design. This limitation is known as the Shockley-Queisser limit and methods to design solar cells to circumvent it have been creative, with a significant part of the field focused on quantum dot (QD) based systems. With theoretical efficiencies ranging between 44 and 67% for one sun concentration, QD solar cell designs are clearly superior to the limits of 1st generation solar cells. However, maximum achieved efficiencies for QD-based designs are far …
Heavy Truck Collision With Bridge Piers, Ran Cao
Heavy Truck Collision With Bridge Piers, Ran Cao
Dissertations and Theses
Based on bridge failure data compiled by the New York State Department of Transportation, collision, both caused by vessels and vehicles, is the second leading cause of bridge failures after hydraulic. The current AASHTO-LRFD (2017) specification recommends designing a bridge pier vulnerable to vehicular impacts for an equivalent static force of 2,670-kN (600 kips) applied in a horizontal plane at a distance of 1.5 m (5.0 feet) above the ground level. The vast majority of research studies on vehicular collision with bridge piers have been carried out with single-unit trucks, which are typically classified as medium-duty vehicles weighing about 89 …
Modification Of Lipid Microenvironments On Solid Support Structures For Use In Transmembrane Protein Assays, William J. Houlihan
Modification Of Lipid Microenvironments On Solid Support Structures For Use In Transmembrane Protein Assays, William J. Houlihan
Dissertations and Theses
Gamma-Secretase (γ-secretase) is a transmembrane protease of increasing interest, which has been shown to have significant connections to both cancer and Alzheimer’s disease. γ-secretase cleaves both Notch-1, a transmembrane signaling protein, and Amyloid precursor protein (APP), a transmembrane protein whose cleavage may result in the formation of β-amyloid plaques in the brain. Notch-1 and APP are widely studied proteins that have substantial impacts on the development and proliferation of cancer and Alzheimer’s disease, respectively. Notch-1 partakes in the signaling of apoptosis in damaged and mutated cells, thus its cleavage by γ-secretase within the plasma membrane has ramifications on cell growth …
Translational Modeling Of Non-Invasive Electrical Stimulation, Dennis Quangvinh Truong
Translational Modeling Of Non-Invasive Electrical Stimulation, Dennis Quangvinh Truong
Dissertations and Theses
Seminal work in the early 2000’s demonstrated the effect of low amplitude non-invasive electrical stimulation in people using neurophysiological measures (motor evoked potentials, MEPs). Clinical applications of transcranial Direct Current Stimulation (tDCS) have since proliferated, though the mechanisms are not fully understood. Efforts to refine the technique to improve results are on-going as are mechanistic studies both in vivo and in vitro. Volume conduction models are being applied to these areas of research, especially in the design and analysis of clinical montages. However, additional research on the parameterization of models remains.
In this dissertation, Finite Element Method (FEM) models of …