Engineering Commons^™

A Building Energy Efficiency Optimization Method By Evaluating The Effective Thermal Zones Occupancy, Anna Laura Pisello, Michael Bobker, Franco Cotana

Publications and Research

Building energy efficiency is strongly linked to the operations and control systems, together with the integrated performance of passive and active systems. In new high quality buildings in particular, where these two latter aspects have been already implemented at the design stage, users’ perspective, obtained through post-occupancy assessment, has to be considered to reduce whole energy requirement during service life. This research presents an innovative and low-cost methodology to reduce buildings’ energy requirements through post-occupancy assessment and optimization of energy operations using effective users’ attitudes and requirements as feedback. As a meaningful example, the proposed method is applied to a …

Role Of Epidermal Growth Factor-Triggered Pi3k/Akt Signaling In The Migration Of Medulloblastoma-Derived Cells, Veronica Dudu, Richard A. Able, Jr., Veronica Rotari, Qingjun Kong, Maribel Vazquez

Publications and Research

Medulloblastoma (MB) is the most common brain cancer diagnosed among children. The cellular pathways that regulate MB invasion in response to environmental cues remain incompletely understood. Herein, we examine the migratory response of human MB-derived Daoy cells to different concentration profiles of Epidermal Growth Factor (EGF) using a microfluidic system. Our findings provide the first quantitative evidence that EGF concentration gradients modulate the chemotaxis of MB-derived cells in a dose-dependent manner via the EGF receptor (EGF-R). Data illustrates that higher concentration gradients caused increased number of cells to migrate. In addition, our results show that EGF-induced receptor phosphorylation triggered the …

Mobile First Web And Content Strategy, Stefanie Havelka, David Stevens

Publications and Research

The paradigm shift from the traditional desktop to the mobile web experience is fast approaching, and providing relevant date, location and time-sensitive content to users via mobile devices becomes an essential piece of the overall web strategy. This presentation demonstrates the concepts, techniques and technologies used to develop both the overall mobile content strategy and user experience, as well as the aggregation and delivery of content to both the desktop and mobile form factors from a single content source.

Development Of A Ground Based Remote Sensing Approach For Direct Evaluation Of Aerosol-Cloud Interaction, Bomidi Lakshmi Madhavan, Yuzhe He, Yonghua Wu, Barry Gross, Fred Moshary, Samir Ahmed

Publications and Research

The possible interaction and modification of cloud properties due to aerosols is one of the most poorly understood mechanisms within climate studies, resulting in the most significant uncertainty as regards radiation budgeting. In this study, we explore direct ground based remote sensing methods to assess the Aerosol-Cloud Indirect Effect directly, as space-borne retrievals are not directly suitable for simultaneous aerosol/cloud retrievals. To illustrate some of these difficulties, a statistical assessment of existing multispectral imagers on geostationary (e.g., GOES)/Moderate Resolution Imaging Spectroradiometer (MODIS) satellite retrievals of the Cloud Droplet Effective Radius (Reff) showed significant biases especially at larger solar zenith angles, …

Computational Model Of Neuron-Astrocyte Interputational Model Of Neuron-Astrocyte Interactions During Focal Seizure Generationactions During Focal Seizure Generation, Davide Reato, Mario Cammarota, Lucas C. Parra, Giorgio Carmignoto

Publications and Research

Empirical research in the last decade revealed that astrocytes can respond to neurotransmitters with Ca2+ elevations and generate feedback signals to neurons which modulate synaptic transmission and neuronal excitability. This discovery changed our basic understanding of brain function and provided new perspectives for how astrocytes can participate not only to information processing, but also to the genesis of brain disorders, such as epilepsy. Epilepsy is a neurological disorder characterized by recurrent seizures that can arise focally at restricted areas and propagate throughout the brain. Studies in brain slice models suggest that astrocytes contribute to epileptiform activity by increasing neuronal excitability …

Potential Significance Of Photoexcited No2 On Global Air Quality With The Nmmb/Bsc Chemical Transport Model, O. Jorba, D. Dabdub, Christopher S. Blaszczak-Boxe, C. Pérez, Z. Janjic, J. M. Baldasano, M. Spada, A. Badia, M. Gonçalves

Publications and Research

Atmospheric chemists have recently focused on the relevance of the NO2* + H2O → OH + HONO reaction to local air quality. This chemistry has been considered not relevant for the troposphere from known reaction rates until nowadays. New experiments suggested a rate constant of 1.7 × 10−13 cm3 molecule−1 s−1, which is an order of magnitude faster than the previously estimated upper limit of 1.2 × 10−14 cm3 molecule−1 s−1, determined by Crowley and Carl (1997). Using the new global model, NMMB/BSC Chemical Transport Model (NMMB/BSC-CTM), simulations are presented that assess the potential significance of this chemistry on global …

Validation Of Noaa-Interactive Multisensor Snow And Ice Mapping System (Ims) By Comparison With Ground-Based Measurements Over Continental United States, Christine Chen, Tarendra Lakhankar, Peter Romanov, Sean Helfrich, Al Powell, Reza Khanbilvardi

Publications and Research

In this study, daily maps of snow cover distribution and sea ice extent produced by NOAA’s interactive multisensor snow and ice mapping system (IMS) were validated using in situ snow depth data from observing stations obtained from NOAA’s National Climatic Data Center (NCDC) for calendar years 2006 to 2010. IMS provides daily maps of snow and sea ice extent within the Northern Hemisphere using data from combination of geostationary and polar orbiting satellites in visible, infrared and microwave spectrums. Statistical correspondence between the IMS and in situ point measurements has been evaluated assuming that ground measurements are discrete and continuously …

Using Avhrr-Based Vegetation Health Indices For Estimation Of Potato Yield In Bangladesh, Rahman A., Kaiser Khan, Nir Y. Krakauer, Leonid Roytman, Kogan F.

Publications and Research

We developed a model correlating Advanced Very High Resolution Radiometer (AVHRR)-based Temperature Condition Index (TCI) and Vegetation Condition Index (VCI) with potato yield in Bangladesh. Weekly TCI and VCI Indices for 1993–2005 along with official potato yield statistics were used for model development. We found a strong correlation between inter annual variation in potato yield and TCI and VCI during the critical period of potato growth (vegetative phase and tuber initiation), mid-December to mid-January. Principal component regression (PCR) was used to construct a model to predict potato yield as function of TCI and VCI. The model explained about 75% of …

Sendai Virus-Based Liposomes Enable Targeted Cytosolic Delivery Of Nanoparticles In Brain Tumor-Derived Cells, Veronica Dudu, Veronica Rotari, Maribel Vazquez

Publications and Research

BACKGROUND: Nanotechnology-based bioassays that detect the presence and/or absence of a combination of cell markers are increasingly used to identify stem or progenitor cells, assess cell heterogeneity, and evaluate tumor malignancy and/or chemoresistance. Delivery methods that enable nanoparticles to rapidly detect emerging, intracellular markers within cell clusters of biopsies will greatly aid in tumor characterization, analysis of functional state and development of treatment regimens.

RESULTS: Experiments utilized the Sendai virus to achieve in vitro, cytosolic delivery of Quantum dots in cells cultured from Human brain tumors. Using fluorescence microscopy and Transmission Electron Microscopy, in vitro experiments illustrated that these virus-based …

Aligned Layers Of Silver Nano-Fibers, Andrii B. Golovin, Jeremy Stromer, Liubov Kreminska

Publications and Research

We describe a new dichroic polarizers made by ordering silver nano-fibers to aligned layers. The aligned layers consist of nano-fibers and self-assembled molecular aggregates of lyotropic liquid crystals. Unidirectional alignment of the layers is achieved by means of mechanical shearing. Aligned layers of silver nano-fibers are partially transparent to a linearly polarized electromagnetic radiation. The unidirectional alignment and density of the silver nano-fibers determine degree of polarization of transmitted light. The aligned layers of silver nano-fibers might be used in optics, microwave applications, and organic electronics.

Using Microwave Brightness Temperature Diurnal Cycle To Improve Emissivity Retrievals Over Land, Hamidreza Norouzi, William Rossow, Marouane Temimi, Catherine Prigent, Marzieh Azarderakhsh, Sid Boukabara, Reza Khanbilvardi

Publications and Research

To retrieve microwave land emissivity, infrared surface skin temperatures have been used as surface physical temperature since there is no global information on physical vegetation/soil temperature profiles. However, passive microwave emissions originate fromdeeper layerswith respect to the skin temperature. So, this inconsistency in sensitivity depths between skin temperatures and microwave temperaturesmay introduce a discrepancy in the determined emissivity. Previous studies showed that this inconsistency can lead to significant differences between day and night retrievals of land emissivity which can exceed 10%. This study proposes an approach to address this inconsistency and improve the retrieval of land emissivity using microwave observations …

Analysis Of The Effects Of Snowpack Properties On Satellite Microwave Brightness Temperature And Emissivity Data, Tarendra Lakhankar, Amir E. Azar, Narges Shahroudi, Alfred Powell, Reza Khanbilvardi

Publications and Research

Spatial variations of snowpack properties are an essential component in flood predictions and water resource management. Satellite microwave remote sensing has shown great potential in retrieving snowpack properties such as: snow depth, snow grain size, and snow density. In this research, we investigate the potential of microwave emissivity which is highly influenced by snowpack properties. Brightness temperature and emissivity data generated from HUT (Helsinki University of Technology) microwave emission of snow model were evaluated with satellite microwave measurements. The comparison of the real measurements (in-situ and satellite) with the modeled results shows that the scattering signature (19GHz-37GHz and 19GHz-85GHz) shows …

An Investigation On Cocombustion Behaviors Of Hydrothermally Treated Municipal Solid Waste With Coal Using A Drop-Tube Reactor, Liang Lu, Yuqi Jin, Masato R. Nakamura, Marco J. Castaldi, Kunio Yoshikawa

Publications and Research

This work aims at demonstrating the feasibility of replacing Indonesian coal (INC) with hydrothermally treated municipal solid waste (MSWH) in cocombustion with high ash Indian coal (IC). The combustion efficiencies and emissions (CO, NO) of MSWH, INC and their blends with IC for a series of tests performed under a range of temperatures and air conditions were tested in a drop- tube reactor (DTR). The results showed the following. The combustion efficiency of IC was increased by blending both MSWH and INC and CO emission was reduced with increasing temperature. For NO emission, the blending of MSWH led to the …