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Full-Text Articles in Engineering

Microfluidic Generated Egf-Gradients Induce Chemokinesis Of Transplantable Retinal Progenitor Cells Via The Jak/Stat And Pi3kinase Signaling Pathways., Uchenna J. Unachukwu, Moira Sauane, Maribel Vazquez, Stephen Redenti Dec 2013

Microfluidic Generated Egf-Gradients Induce Chemokinesis Of Transplantable Retinal Progenitor Cells Via The Jak/Stat And Pi3kinase Signaling Pathways., Uchenna J. Unachukwu, Moira Sauane, Maribel Vazquez, Stephen Redenti

Publications and Research

A growing number of studies are evaluating retinal progenitor cell (RPC) transplantation as an approach to repair retinal degeneration and restore visual function. To advance cell-replacement strategies for a practical retinal therapy, it is important to define the molecular and biochemical mechanisms guiding RPC motility. We have analyzed RPC expression of the epidermal growth factor receptor (EGFR) and evaluated whether exposure to epidermal growth factor (EGF) can coordinate motogenic activity in vitro. Using Boyden chamber analysis as an initial high-throughput screen, we determined that RPC motility was optimally stimulated by EGF concentrations in the range of 20-400 ng/ml, with decreased …


Assessing The Performance Of A Northern Gulf Of Mexico Tidal Model Using Satellite Imagery, Stephen C. Medeiros, Scott C. Hagen, Naira Chaouch, Jesse Feyen, Marouane Temimi, John F. Weishampel, Yuji Funakoshi, Reza Khanbilvardi Nov 2013

Assessing The Performance Of A Northern Gulf Of Mexico Tidal Model Using Satellite Imagery, Stephen C. Medeiros, Scott C. Hagen, Naira Chaouch, Jesse Feyen, Marouane Temimi, John F. Weishampel, Yuji Funakoshi, Reza Khanbilvardi

Publications and Research

Tidal harmonic analysis simulations along with simulations spanning four specific historical time periods in 2003 and 2004 were conducted to test the performance of a northern Gulf of Mexico tidal model. A recently developed method for detecting inundated areas based on integrated remotely sensed data (i.e., Radarsat-1, aerial imagery, LiDAR, Landsat 7 ETM+) was applied to assess the performance of the tidal model. The analysis demonstrates the applicability of the method and its agreement with traditional performance assessment techniques such as harmonic resynthesis and water level time series analysis. Based on the flooded/non-flooded coastal areas estimated by the integrated remotely …


Evaluating Satellite Products For Precipitation Estimation In Mountain Regions: A Case Study For Nepal, Nir Y. Krakauer, Soni M. Pradhanang, Tarendra Lakhankar, Ajay K. Jha Aug 2013

Evaluating Satellite Products For Precipitation Estimation In Mountain Regions: A Case Study For Nepal, Nir Y. Krakauer, Soni M. Pradhanang, Tarendra Lakhankar, Ajay K. Jha

Publications and Research

Precipitation in mountain regions is often highly variable and poorly observed, limiting abilities to manage water resource challenges. Here, we evaluate remote sensing and ground station-based gridded precipitation products over Nepal against weather station precipitation observations on a monthly timescale. We find that the Tropical Rainfall Measuring Mission (TRMM) 3B-43 precipitation product exhibits little mean bias and reasonable skill in giving precipitation over Nepal. Compared to station observations, the TRMM precipitation product showed an overall Nash-Sutcliffe efficiency of 0.49, which is similar to the skill of the gridded station-based product Asian Precipitation-Highly Resolved Observational Data Integration Towards Evaluation of Water …


Intradepartmental Collaboration To Improve The Quality Of Engineering Drawings Created By Students In Senior Design Project, Andy S. Zhang, Gaffar Gailani Jun 2013

Intradepartmental Collaboration To Improve The Quality Of Engineering Drawings Created By Students In Senior Design Project, Andy S. Zhang, Gaffar Gailani

Publications and Research

Engineers use engineering graphics to describe their design, to exchange ideas, and to communicate with others. As an important communication tool, most engineering department commits at least two courses on engineering graphics. The mechanical engineering technology at the college offers three engineering graphics courses for its associate degree program. The objective is to give students opportunity to get familiar with different type of engineering graphics from 2D to 3D and from general graphics to mechanical engineering specific graphics gradually so they can apply these engineering graphics skills in their senior courses such as in machine design. Despite the extensive offering …


Attracting College And High School Students To Study Engineering Technology Through Hands-On Mechatronics Product Design Projects, Andy S. Zhang, Sidi Berri, Iem H. Heng, Farrukh Zia Jun 2013

Attracting College And High School Students To Study Engineering Technology Through Hands-On Mechatronics Product Design Projects, Andy S. Zhang, Sidi Berri, Iem H. Heng, Farrukh Zia

Publications and Research

Attracting College and High School Students to Study Engineering Technology Engineering technology encompasses many engineering technology fields: mechanical engineering technology, electrical engineering technology, and computer engineering technology, etc. This poster presents the work on using hands-on mechatronics design activities to attract high school and college students to study engineering technology. Technology education has been a key in producing college graduates to work in today’s fast paced, highly competitive public and private enterprises. Unfortunately, the supply of qualified workforce has been reduced in the United States due to the steady drop of enrollment of college and high school students in STEM …


Biomarkers For Brain Disorders Electrochemically Detected By Broderick Probe Microelectrodes/Biosensors, Waqas Saleem, Patricia A. Broderick Jan 2013

Biomarkers For Brain Disorders Electrochemically Detected By Broderick Probe Microelectrodes/Biosensors, Waqas Saleem, Patricia A. Broderick

Publications and Research

Here, we present results from two independent studies carried out using Neuromolecular Imaging (NMI) with miniature BRODERICK PROBE® biosensors. In the first study, we imaged neurotransmitters and neurochemicals in human epilepsy patients intraoperatively during early and late neurodegeneration. In the second study, we imaged neurotransmitters and neurochemicals in an experimental murine model using animals with and without neurodegeneration caused by Parkinson’s disease (PD). We compared our results derived from animals with lesioned group (PD) with non-lesioned group (non-PD), using the same in vivo NMI paradigm. NMI biotechnology enabled neurotransmitters, neuropeptides and neurochemical imaging of dopamine (DA), serotonin (5-HT), homovanillic acid …


Crest-Snow Field Experiment: Analysis Of Snowpack Properties Using Multi-Frequency Microwave Remote Sensing Data, Tarendra Lakhankar, J. Munoz, A.M. Powell, N.Y. Krakauer, W.B. Rossow, Reza Khanbilvardi Jan 2013

Crest-Snow Field Experiment: Analysis Of Snowpack Properties Using Multi-Frequency Microwave Remote Sensing Data, Tarendra Lakhankar, J. Munoz, A.M. Powell, N.Y. Krakauer, W.B. Rossow, Reza Khanbilvardi

Publications and Research

The CREST-Snow Analysis and Field Experiment (CREST-SAFE) was carried out during January–March 2011 at the research site of the National Weather Service office, Caribou, ME, USA. In this experiment dual-polarized microwave (37 and 89 GHz) observations were accompanied by detailed synchronous observations of meteorology and snowpack physical properties. The objective of this long-term field experiment was to improve understanding of the effect of changing snow characteristics (grain size, density, temperature) under various meteorological conditions on the microwave emission of snow and hence to improve retrievals of snow cover properties from satellite observations. In this paper we present an overview of …


Superconductivity In An Inhomogeneous Bundle Of Metallic And Semiconducting Nanotubes, Ilya Grigorenko, Anvar Zakhidov Jan 2013

Superconductivity In An Inhomogeneous Bundle Of Metallic And Semiconducting Nanotubes, Ilya Grigorenko, Anvar Zakhidov

Publications and Research

Using Bogoliubov-de Gennes formalism for inhomogeneous systems, we have studied superconducting properties of a bundle of packed carbon nanotubes, making a triangular lattice in the bundle's transverse cross-section. The bundle consists of a mixture of metallic and doped semiconducting nanotubes, which have different critical transition temperatures. We investigate how a spatially averaged superconducting order parameter and the critical transition temperature depend on the fraction of the doped semiconducting carbon nanotubes in the bundle. Our simulations suggest that the superconductivity in the bundle will be suppressed when the fraction of the doped semiconducting carbon nanotubes will be less than 0.5, which …