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Full-Text Articles in Engineering

Ultrahigh Field Magnetic Resonance Imaging – Technical Development And Translational Applications, Judy Alper Jan 2016

Ultrahigh Field Magnetic Resonance Imaging – Technical Development And Translational Applications, Judy Alper

Dissertations and Theses

Magnetic resonance imaging (MRI) may be used to provide detailed images of the human body with excellent soft tissue contrast. Alongside its current widespread clinical applications for diagnosis and treatment, MRI allows researchers to measure structure and function of different tissue types in order to advance our understanding of human biology and enable new medical applications of MRI. In particular, diseases affecting nerves and vessels, such as trigeminal neuralgia, with uncertain etiology can be studied using multiple MRI modalities so that treatment planning can we more effective and patient outcomes can be improved. Ultrahigh field MRI scanners, such as those …


Mechanistic-Empirical Pavement Design Guide (Mepdg) Method Implemented To Estimate Damage In Flexible And Rigid Pavements, Tenzin Gusto Jan 2016

Mechanistic-Empirical Pavement Design Guide (Mepdg) Method Implemented To Estimate Damage In Flexible And Rigid Pavements, Tenzin Gusto

Dissertations and Theses

The implementation of the Empirical-Mechanistic Pavement Design Guide (MEPDG) method for flexible and rigid pavements requires numerous input parameters. Most of these parameters can be easily determined while some require best estimates that are usually extracted from available literature. This thesis identifies the most critical input parameters in terms of their effects on the damage of pavements and their influence on the determination of the number of corrective maintenance cycles to be performed during the design life of pavements. It was found that for flexible pavement, change in the average monthly temperature by as little as results in large differences …


Discrete Model For Cancer Tumor Growth And Effect Of Chemotherapy, Karim Virani Jan 2016

Discrete Model For Cancer Tumor Growth And Effect Of Chemotherapy, Karim Virani

Dissertations and Theses

Many mathematical models have focused on growth of a single tumor with their spreading rate with some have included its metastasis. Some of the earlier models focus on exponential growth and its shift with time on to a linear model. The Gompertzian model involves a quadratic terms and that limit growth. We looked into Iwata et al paper it discusses a different model and takes into account the growth and metastasis of a tumor population but does not look into tumor shrinking or chemotherapy. Our new model focuses on the extending Iwata et al model to take into account tumor …


Direct Current Stimulation Modulates Ltp And Ltd: Activity-Dependence And Dendritic Effects, Gregory Kronberg Jan 2016

Direct Current Stimulation Modulates Ltp And Ltd: Activity-Dependence And Dendritic Effects, Gregory Kronberg

Dissertations and Theses

Transcranial direct current stimulation (tDCS) has been reported to improve various forms of learning in humans. Stimulation is often applied during training, producing lasting enhancements that are specific to the learned task. These learning effects are thought be mediated by altered synaptic plasticity. However, the effects of DCS during the induction of endogenous synaptic plasticity remain largely unexplored. To model endogenous plasticity I induced long-term potentiation (LTP) and depression (LTD) at Schaffer collateral synapses in CA1 of rat hippocampal slices. When induction was paired with concurrent DCS, the resulting plasticity was biased towards potentiation, such that LTP was enhanced and …


Innovative System For Seismic Control Strategies, Seyed Ali Razavi Jan 2016

Innovative System For Seismic Control Strategies, Seyed Ali Razavi

Dissertations and Theses

Among various alternative approaches, installing auxiliary damping devices such as tuned mass dampers (TMDs) is a very reliable solution to mitigate wind-induced vibration of tall buildings. However, regardless of the different distribution strategies, installing TMD systems means adding additional masses to tall buildings. A valuable space on top of tall buildings is sacrificed to contain a large bulky mass, which is not aesthetically pleasing. Furthermore, increasing the mass of tall buildings by installing extra mass systems is not time and cost effective process. In order to address the issues, this paper investigates the utilization of feasible alternative for the purpose …